Search results for "Plate"

PDGFRα-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling

2006

Neurons and oligodendrocytes are produced in the adult brain subventricular zone (SVZ) from neural stem cells (B cells), which express GFAP and have morphological properties of astrocytes. We report here on the identification B cells expressing the PDGFRalpha in the adult SVZ. Specifically labeled PDGFRalpha expressing B cells in vivo generate neurons and oligodendrocytes. Conditional ablation of PDGFRalpha in a subpopulation of postnatal stem cells showed that this receptor is required for oligodendrogenesis, but not neurogenesis. Infusion of PDGF alone was sufficient to arrest neuroblast production and induce SVZ B cell proliferation contributing to the generation of large hyperplasias wi…

Mixed finite elements for nonlocal elastic multilayered composite plate refined theories

2020

Abstract A novel mixed finite element formulation for the layerwise analysis of nonlocal multilayered composite plates is presented. The finite elements are formulated starting from the weak form of a set of governing equations for the laminate layers that were deduced via the Reissner Mixed Variational Theorem. The primary variables, namely displacements and out-of-plane stresses, are expressed at layer level as through-the-thickness expansions of suitable selected functions with coefficients approximated by the finite element scheme. The through-the-thickness expansion order is considered as a free parameter. This way, finite elements for different refined higher order plate theories can …

Joint use of cardio-embolic and bleeding risk scores in elderly patients with atrial fibrillation

2013

Background Scores for cardio-embolic and bleeding risk in patients with atrial fibrillation are described in the literature. However, it is not clear how they co-classify elderly patients with multimorbidity, nor whether and how they affect the physician's decision on thromboprophylaxis. Methods Four scores for cardio-embolic and bleeding risks were retrospectively calculated for ≥ 65 year old patients with atrial fibrillation enrolled in the REPOSI registry. The co-classification of patients according to risk categories based on different score combinations was described and the relationship between risk categories tested. The association between the antithrombotic therapy received and t…

Mortality rate and risk factors for gastrointestinal bleeding in elderly patients

2019

Abstract Background Gastrointestinal bleeding (GIB) is burdened by high mortality rate that increases with aging. Elderly patients may be exposed to multiple risk factors for GIB. We aimed at defining the impact of GIB in elderly patients. Methods Since 2008, samples of elderly patients (age ≥ 65 years) with multimorbidity admitted to 101 internal medicine wards across Italy have been prospectively enrolled and followed-up (REPOSI registry). Diagnoses of GIB, length of stay (LOS), mortality rate, and possible risk factors, including drugs, index of comorbidity (Cumulative Illness Rating Scale [CIRS]), polypharmacy, and chronic diseases were assessed. Adjusted multivariate logistic regressio…

Assessment of Renewable Sources for the Energy Consumption in Malta in the Mediterranean Sea

2016

The main purpose of this paper is to analyze the energy production in the Maltese islands, focusing on the employment of renewable energies in order to increase their energy independence. The main renewable source here proposed is wave energy: thanks to a strategic position, Malta will be able to produce electrical energy using an innovative type of Wave Energy Converter (WEC) based on the prototype of a linear generator realized by University of Palermo. The use of this new technology will be able to cut down the electrical energy production from traditional power plants and, consequently, the greenhouse gas emissions (GHG). Wave energy source and off-shore photovoltaic (PV) technology are…

Responsiveness to change and reliability of measurement of radiographic joint space width in osteoarthritis of the knee: a systematic review

2011

Import JabRef | WosArea Orthopedics; Rheumatology; International audience; Objective: The goal of this systematic review was to report the responsiveness to change and reliability of conventional radiographic joint space width (JSW) measurement. Method: We searched the PubMed and Embase databases using the following search criteria: [osteoarthritis (OA) (MeSH)] AND (knee) AND (X-ray OR radiography OR diagnostic imaging OR radiology OR disease progression) AND (joint space OR JSW or disease progression). We assessed responsiveness by calculating the standardized response mean (SRM). We assessed reliability using intra- and inter-reader intra-class correlation (ICC) and coefficient of variati…

Discovery of hard phase lags in the pulsed emission of GRO J1744-28

2016

We report on the discovery and energy dependence of hard phase lags in the 2.14 Hz pulsed profiles of GRO J1744-28. We used data from XMM-Newton and NuSTAR. We were able to well constrain the lag spectrum with respect to the softest (0.3--2.3 keV) band: the delay shows increasing lag values reaching a maximum delay of $\sim$ 12 ms, between 6 and 6.4 keV. After this maximum, the value of the hard lag drops to 7 ms, followed by a recovery to a plateau at 9 ms for energies above 8 keV. NuSTAR data confirm this trend up to 30 keV, but the measurements are statistically poorer, and therefore, less constraining. The lag-energy pattern up to the discontinuity is well described by a logarithmic fun…

Aportaciones biográficas y artísticas sobre le platero Bertomeu Coscollá (ca. 1350-1429)

2016

Deep-rooted “thick skinned” model for the High Atlas Mountains (Morocco). Implications for the structural inheritance of the southern Tethys passive …

2006

A re-interpretation of the deep structure of the High Atlas is presented through integration of geophysical and geological data, highlighting the architectural significance of the southern Tethys palaeomargin. Previous crustal models suggest the occurrence of a flat intra-crustal detachment at a depth of � 20 km, a zone where surface thrusts merge and below which the lower High Atlas crust appears continuous. However, within this study seismic refraction data, electrical resistivity surveys and gravity modelling all appear to detect a jump in crustal thickness between the High Atlas and the northern plains. We interpret these data as penetration by thrusts within the ‘‘South-Atlasic fault’’…

Asymmetric continental deformation during South Atlantic rifting along southern Brazil and Namibia

2017

Abstract Plate restoration of South America and Africa to their pre-breakup position faces the problem of gaps and overlaps between the continents, an issue commonly solved with implementing intra-plate deformation zones within South America. One of these zones is often positioned at the latitude of SE/S Brazil. However, geological evidence for the existence of a distinct zone in this region is lacking, which is why it remains controversial and is not included in all modeling studies. In order to solve this problem we present a study of multiple geological aspects of both parts of the margin, SE/S Brazil and its conjugate part NW Namibia at the time of continental breakup. Our study highlig…