Search results for "Polyp"

showing 10 items of 1415 documents

Sobre la vegetación de la alianza Homalothecio-Polypodion serrati en las montañas valencianas

1983

Se han estudiado las comunidades de la alianza Homalothecio-Polypodion serrati en las montañas de la región valenciana y alrededores, encontrándose que las mismas pueden atribuirse a cuatro asociaciones: Anomodonio-Polypodietum serrati, Saxifragetum cossonianae, Saxifragetum latepetiolatae y Homalothecio-Asplenietum fontani. Se presentan sendas tablas fitosociológicas de cada una de las tres últimas, de las cuales se comentan, asimismo, sus principales notas características. The communities included in the alliance Homalothecio-Polypodio serrati are studied in Valencia region and neighbouring areas. 4 associations can be assigned to them: Anomodonio-Polypodietum serrati, Saxifragetum cosson…

:CIENCIAS DE LA VIDA::Biología vegetal (Botánica) [UNESCO]Homalothecio-Polypodion serratiValenciaHomalothecio-Polypodion serrati ; Valencia ; Tablas fitosociológicasUNESCO::CIENCIAS DE LA VIDA::Biología vegetal (Botánica)Tablas fitosociológicas
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Botāniskā dārza sekcijas “Augu daudzveidības pētījumi ex situ” un “Augu selekcija un introdukcija” tēžu krājums

2022

Latvijas Universitātes 80. starptautiskās zinātniskās konferences Botāniskā dārza sekcijas “Augu daudzveidības pētījumi ex situ” un “Augu selekcija un introdukcija” referāti tika nolasīti 2022. gada 1. februārī plkst. 13:00 tiešsaistē.

:NATURAL SCIENCES::Biology [Research Subject Categories]Zantedeschia sp.rododendru selekcijaziemcietespurvu veģetācijaPulsatilla patensVaccinium vitis-idaeahibrīdās sugasPolyphagotarsonemus latus
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Strategies to gain novel Alzheimer’s disease diagnostics and therapeutics using modulators of ABCA transporters

2021

Adenosine-triphosphate-(ATP)-binding cassette (ABC) transport proteins are ubiquitously present membrane-bound efflux pumps that distribute endo- and xenobiotics across intra- and intercellular barriers. Discovered over 40 years ago, ABC transporters have been identified as key players in various human diseases, such as multidrug-resistant cancer and atherosclerosis, but also neurodegenerative diseases, such as Alzheimer���s disease (AD). Most prominent and well-studied are ABCB1, ABCC1, and ABCG2, not only due to their contribution to the multidrug resistance (MDR) phenotype in cancer, but also due to their contribution to AD. However, our understanding of other ABC transporters is limited…

ABCG2 (BCRP)Multitarget inhibitor (PANABC)Broad-spectrum modulatorPolypharmacologyActivationNeurosciences. Biological psychiatry. NeuropsychiatryAmyloid-beta (Aβ / Abeta)ABCA2ABCA5ArticleABCA7InductionABCB1 (P-gp)Pattern analysisDownregulationPET Tracer (PETABC)ABC transporterABCA1 (ABC1)Rational drug design and developmentAlzheimer’s diseaseRC321-571ABCC1 (MRP1)InhibitionFree neuropathology
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Elucidation of antioxidant properties of wood bark derived saturated diarylheptanoids: a comprehensive (DFT-supported) understanding.

2013

A series of diarylheptanoids, namely 1,7-bis-(3,4-dihydroxyphenyl)-heptan-3-one-5-O-D-xylopyranoside (oregonin), 1,7-bis-(3,4-dihydroxyphenyl)-3-hydroxyheptane-5-O-β-D-xylopyranoside and 1,7-bis-(4-hydroxyphenyl)-heptane-3-one-5-O-β-D-glucopyranoside (platyphylloside), were isolated from the bark of alder family trees, a species widely spread over in Europe. As antioxidants, these natural polyphenols have a promising potential in various fields of application, but their redox reactivity is insufficiently characterized. In this work, their antioxidant activity is described using assays based on DPPH and ABTS(+) radical scavenging, oxygen anion radicals (O2(-)) quenching. The standardized ORA…

ABTSAntioxidantMolecular modelDPPHmedicine.medical_treatmentDiarylheptanoidPlant ScienceGeneral MedicineHorticultureAlnusBiochemistryRedoxWoodAntioxidantschemistry.chemical_compoundStructure-Activity RelationshipchemistryPolyphenolDiarylheptanoidsmedicinePlant BarkOrganic chemistryMolecular BiologyDiarylheptanoidsPhytochemistry
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Improved bioaccessibility and antioxidant capacity of olive leaf ( Olea europaea L.) polyphenols through biosorption on Saccharomyces cerevisiae

2016

Abstract Olive ( Olea europaea L.) leaves (OL) are natural by-products that can be used as an advantageous rich source of bioactive compounds, especially polyphenols. This study investigated the potential use of Saccharomyces cerevisiae as a new carrier of OL antioxidants and a means to protect their bioactivity during simulated gastrointestinal digestion. The biosorption on S. cerevisiae allowed the recovery of 25.17 mg/g and 49.40% of the polyphenols from olive leaf (var. Chemlali ) infusions. Both infusions and suspensions before and after biosorption were analyzed for total soluble polyphenols and total antioxidant capacity (oxygen radical absorbance capacity (ORAC) and trolox equivalen…

ABTSOxygen radical absorbance capacitybiologyChemistry010401 analytical chemistryBiosorptionTrolox equivalent antioxidant capacityfood and beverages04 agricultural and veterinary sciencesbiology.organism_classification040401 food science01 natural sciences0104 chemical scienceschemistry.chemical_compound0404 agricultural biotechnologyOlive leafBiochemistryPolyphenolOleaHydroxytyrosolFood scienceAgronomy and Crop ScienceIndustrial Crops and Products
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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
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Abemaciclib-associated Diarrhea: An Exploratory Analysis of Real-life Data

2023

Background/Aim: Abemaciclib is a cyclin-dependent kinase 4/6 inhibitor approved in combination with endocrine therapy for treating hormone receptor-positive and human epidermal growth factor receptor 2-negative early and advanced breast cancer patients. The safety profile of abemaciclib is characterized by frequent gastrointestinal toxicity, especially diarrhea. Therefore, we performed an exploratory analysis of clinical factors that may be potentially associated with diarrhea in patients treated with abemaciclib plus endocrine therapy. Patients and Methods: Factors potentially predisposing to diarrhea were selected, such as age ≥70 years, concomitant medications and diseases, diet, and use…

AbemaciclibCancer ResearchOncologyagediarrheaGeneral Medicinepolypharmacycomorbiditiesdiet
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Elucidation of the biosynthesis and degradation of allantofuranone by isotopic labelling and fermentation of modified precursors.

2010

Feeding experiments with the ascomycete Allantophomopsis lycopodina indicated that the potent fungistatic allantofuranone is biosynthesized from phenylalanine. Further experiments with synthetic precursors gave evidence that the naturally occurring polyporic acid serves as a key intermediate in the biosynthesis. In addition to the formation of allantofuranone, its abiotic and metabolic degradation were investigated.

Abiotic componentAntifungal AgentsOrganic ChemistryFungiPolyporic acidPhenylalanineBiologyBiochemistryIsotopic labelingchemistry.chemical_compoundBiosynthesischemistryBiochemistry4-ButyrolactoneLabellingIsotope LabelingFermentationMolecular MedicineDegradation (geology)FermentationMolecular BiologyChembiochem : a European journal of chemical biology
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Polypyrrole films functionalized with pendant titanocene dichloride complexes: Ellipsometric study of the electropolymerization process

2007

Electrochemical and ellipsometric methods have been used to study the electropolymerization process of a functionalized monomer, Tc3Py (in which pyrrole is covalently bonded with titanocene dichloride complex) on platinum electrode from a dilute monomer solution in acetonitrile. The deposition has been performed in the potentiodynamic regime. A new method for the acquisition and treatment of ellipsometric data has been proposed which allowed us to analyze the evolution of the film properties at each potential. The model of a single uniform layer was unable to describe the ellipsometric experimental observations with the necessary precision. A proper fitting of the data has been achieved con…

Absorbancechemistry.chemical_compoundMonomerchemistryAbsorption spectroscopyEllipsometryGeneral Chemical EngineeringElectrodeElectrochemistryAnalytical chemistryMolar absorptivityPolypyrroleElectrode potentialElectrochimica Acta
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On the variations of acoustic absorption peak with particle velocity in micro-perforated panels at high level of excitation.

2010

The acoustic behavior of micro-perforated panels (MPP) is studied theoretically and experimentally at high level of pressure excitation. A model based on Forcheimer's regime of flow velocity in the perforations is proposed. This model is valid at relatively high Reynolds numbers and low Mach numbers. The experimental method consists in measuring the acoustical pressure at three different positions in an impedance tube, the two measurement positions usually considered in an impedance tube and one measurement in the vicinity of the rear surface of the MPP. The impedance tube is equipped with a pressure driver instead of the usual loudspeaker and capable of delivering a high sound pressure lev…

Absorption (acoustics)Materials scienceAcoustics and UltrasonicsAcoustics[ PHYS.COND.CM-MS ] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]FOS: Physical sciencesPhysics - Classical PhysicsPolypropylenes01 natural sciences010305 fluids & plasmasAbsorption[SPI]Engineering Sciences [physics]symbols.namesakeMotionArts and Humanities (miscellaneous)0103 physical sciencesPressureParticle velocitySound pressure010301 acoustics[ PHYS.MECA.ACOU ] Physics [physics]/Mechanics [physics]/Acoustics [physics.class-ph][SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph][ SPI.ACOU ] Engineering Sciences [physics]/Acoustics [physics.class-ph]Construction MaterialsAirFluid Dynamics (physics.flu-dyn)Classical Physics (physics.class-ph)Reynolds numberPhysics - Fluid DynamicsAcousticsModels TheoreticalSound intensity[PHYS.MECA.ACOU]Physics [physics]/Mechanics [physics]/Acoustics [physics.class-ph]Mach numberFlow velocityNonlinear DynamicsSteelFacility Design and Construction[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]symbolsLinear ModelsAcoustic impedanceNoisePorosityThe Journal of the Acoustical Society of America
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