Search results for "Polyphenols"

showing 10 items of 293 documents

Measurement of white wines resistance against oxidation by Electron Paramagnetic Resonance spectroscopy

2018

International audience; Free radical theory of aging hypothesizes that oxygen-derived radicals are responsible for the storage-related flavor instability in wine. In an optimal situation, a balanced-distribution exists between oxidants and antioxidants among wines intrinsic/extrinsic metabolites. Based on the kinetic study of POBN-1-hydroxyethyl spin adduct (POBN-1-HER) formation in wines initiated via the Fenton reaction, a novel tool based on EPR spin trapping methodology was developed to quantify wines resistance against oxidation. Antioxidant capacities of wines were evaluated according to POBN-1-HER maximum signal intensity (Imax POBN-1-HER) and rate formation (r(POBN-1-HER)) kinetic p…

Electron paramagnetic resonance spectroscopyAntioxidantFree Radicalssulfur-dioxidemedicine.medical_treatmentRadicalWinePhotochemistry01 natural sciencesAnalytical ChemistryAdductlaw.invention0404 agricultural biotechnologylaw[SDV.IDA]Life Sciences [q-bio]/Food engineeringmedicineAging potentialElectron paramagnetic resonanceFlavorFree-radical theory of agingdegradationWineparametersChemistryfree-radical generation010401 analytical chemistryRadical chemistryElectron Spin Resonance Spectroscopyfood and beveragesPolyphenolstemperature04 agricultural and veterinary sciencesGeneral Medicine040401 food science0104 chemical sciencescolorElectron Paramagnetic ResonancearomaSulfur dioxideidentificationSpin Labelsepr spectroscopyOxidation-ReductionFood Science
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Non-flavonoid polyphenols in osteoporosis: preclinical evidence

2021

The development of progressive osteopenia and osteoporosis (OP) is due to the imbalance between bone resorption and bone formation, determining a lower bone resistance, major risks of fractures, with consequent pain and functional limitations. Flavonoids, a class of polyphenols, have been extensively studied for their therapeutic activities against bone resorption, but less attention has been given to a whole series of molecules belonging to the polyphenolic compounds. However, these classes have begun to be studied for the treatment of OP. In this systematic review, comprehensive information is provided on non-flavonoid polyphenolic compounds, and we highlight pathways implicated in the ac…

Endocrinology Diabetes and MetabolismOsteoporosisFlavonoid030209 endocrinology & metabolismBioinformaticsBone resorption03 medical and health sciences0302 clinical medicineEndocrinologypolyphenolic compoundsSettore BIO/13 - Biologia ApplicataOsteogenesisSettore BIO/10 - Biochimicabone erosive diseasesHumansMedicineBone formationBone ResorptionProgressive osteopeniaFlavonoidschemistry.chemical_classificationepigeneticsbusiness.industryPolyphenolsfood and beveragesmedicine.diseaseSettore BIO/18 - GeneticachemistryPolyphenolosteoclastosteoblastOsteoporosisbusinessTrends in Endocrinology & Metabolism
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Application of ultrasound as clean technology for extraction of specialized metabolites from stinging nettle (Urtica dioica L.)

2022

Nettle is a highly valued medicinal plant that is still largely neglected, both in terms of nutrition and use for pharmacological purposes. Tinctures, i.e., alcoholic extracts, are becoming increasingly popular nettle products, mainly because they allow better availability of phytochemicals and their stability over a longer period of time. The production of alcoholic extracts is a chemically demanding process that is still usually carried out using conventional techniques, which have numerous drawbacks. The use of green technologies such as ultrasound-assisted extraction (UAE), which is characterized by high efficiency of phytochemical extraction, shorter treatment time, and a much lower en…

FarmacologiaNutrition and DieteticsEndocrinology Diabetes and Metabolismultrasound-assisted extraction ; ethanolic extracts ; polyphenols ; ascorbic acid ; pigments ; antioxidant capacityPlantes medicinalsFood Science
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Antioxidant properties of polyphenol-rich cocoa products industrially processed

2010

Fermentation and roasting are the main causes of polyphenol degradation during the process for obtaining cocoa products. In the present study, a process for obtaining polyphenol-rich cocoa products on an industrial scale is described. The process avoids the fermentation and roasting steps and includes a step for the inactivation of the enzyme Polyphenol Oxidase (PPO), which helps preserve the polyphenol content present in the raw cocoa bean. In addition, our study evaluates the antioxidant capacity and characterizes the flavonoid profile of the polyphenol-rich cocoa products obtained from the natural polyphenolrich cocoa cake. Using different protocols, we have obtained three cocoa extracts…

Farmacología y FarmaciaAntioxidantCIENCIAS MÉDICAS Y DE LA SALUDDPPHmedicine.medical_treatmentPolyphenol oxidasechemistry.chemical_compoundfoodCocoamedicineOrganic chemistryTheobroma cacaoFood scienceCiencias ExactasABTSChemistryfood and beveragesPolyphenolsCOCOA BEANAscorbic acidfood.foodMedicina BásicaPolyphenolTroloxAntioxidantTheobroma CacaoFood Science
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Recovery of oil with unsaturated fatty acids and polyphenols from chaenomelessinensis (Thouin) Koehne: Process optimization of pilot-scale subcritica…

2017

The potential effects of three modern extraction technologies (cold-pressing, microwaves and subcritical fluids) on the recovery of oil from Chaenomelessinensis (Thouin) Koehne seeds have been evaluated and compared to those of conventional chemical extraction methods (Soxhlet extraction). This oil contains unsaturated fatty acids and polyphenols. Subcritical fluid extraction (SbFE) provided the highest yield—25.79 g oil/100 g dry seeds—of the three methods. Moreover, the fatty acid composition in the oil samples was analysed using gas chromatography–mass spectrometry. This analysis showed that the percentages of monounsaturated (46.61%), and polyunsaturated fatty acids (42.14%), after appl…

FlavonoidPharmaceutical ScienceMass spectrometry01 natural sciencesGas Chromatography-Mass SpectrometryArticleAnalytical Chemistrylcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryResponse surface methodologyDrug DiscoveryPlant OilsProcess optimizationPhysical and Theoretical Chemistry<i>Chaenomelessinensis</i> (Thouin) Koehne seed oil; subcritical fluid extraction; response surface methodology; fatty acid composition; polyphenol contentMicrowavesRosaceaeChaenomelessinensis (Thouin) Koehne seed oil; Fatty acid composition; Polyphenol content; Response surface methodology; Subcritical fluid extraction; Organic Chemistrychemistry.chemical_classificationChromatography010405 organic chemistryPolyphenol contentExtraction (chemistry)Organic ChemistryPilot scalePolyphenols04 agricultural and veterinary sciences040401 food scienceChaenomelessinensis (Thouin) Koehne seed oil0104 chemical scienceschemistryChemistry (miscellaneous)PolyphenolFatty Acids UnsaturatedMolecular MedicineFatty acid compositionFatty acid compositionSubcritical fluid extractionPolyunsaturated fatty acid
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Supercritical fluid extraction and HPLC determination of relevant polyphenolic compounds in grape skin.

2005

The polyphenols determined are: (+)-catechin, (-)-epicatechin, rutin, quercetin and trans-resveratrol. Suitable conditions of supercritical fluid extraction were established using ethanol as a modifier of the polarity solvent (supercritical carbon dioxide). Final extraction conditions were: 20% v/v ethanol, 60degreesC, 250 bars and flow rate 2 mL/min. Static step time and dynamic step time were established using a selected grape skin sample. The extract was collected in water; the more polar polyphenols ((+)-catechin and (-)-epicatechin) remain in solution but rutin, quercetin and trans-resveratrol precipitate in this medium, thereby the solution of the extracted polyphenols was filtered. (…

FlavonoidsSupercritical carbon dioxideChromatographyEthanolChemistryExtraction (chemistry)Supercritical fluid extractionPolyphenolsFiltration and SeparationChromatography Supercritical FluidHigh-performance liquid chromatographySupercritical fluidAnalytical ChemistryAcetic acidchemistry.chemical_compoundRutinPhenolsFruitVitisQuercetinChromatography High Pressure LiquidJournal of separation science
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Mind the gap—deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites—a position paper focusing on …

2015

This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial-NoDerivs Licence.-- et al.

Food processingColonFood HandlingMetabolitePhytochemicalsBiological AvailabilityReviewsReviewPharmacologyBiologymedicine.disease_causeGastrointestinal epitheliumchemistry.chemical_compoundSDG 3 - Good Health and Well-beingBiotransformationsIntestine SmallmedicineHumansTissue DistributionCarotenoidBiotransformationchemistry.chemical_classificationMicrobiotaPolyphenolsCarotenoidsGastrointestinal MicrobiomeBioavailabilityTransportersIntestinal AbsorptionSolubilityPhytochemicalBiochemistrychemistryPolyphenol/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingEffluxOxidative stressMixed dietFood ScienceBiotechnologyMolecular Nutrition &amp; Food Research
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Evaluation of antioxidant properties and assessment of genetic diversity of Capparis spinosa cultivated in Pantelleria Island.

2017

Capparis spinosa is a wild and cultivated bush, which grows mainly in the Mediterranean Basin. Unopened flower buds, called capers are used in the Mediterranean cuisine as flavoring for meat, vegetable and other foods. Several studies evaluated bioactive component and antioxidant activity of Capparis spinosa, increasing the market demand and the economic importance of capers.The aim of this work was to evaluate the contents of bioactive compounds in floral buds fermented in salt of C. spinosa collected from different areas of Pantelleria Island (Italy), testing the effect on healthy function as total antioxidant compounds. Hydrophilic extracts of C. spinosa from Pantelleria Island were char…

Genetic diversityABTSBioactive componentDPPHCapparis spinosaPolyphenolsCapparis spinosa Caper antioxidant polyphenols Bioactive components HPLC-MS AFLP ABTS Folin & Ciocalteu ORAC DPPH flavonoidsMediterranean Basinfood.foodHPLC-MSSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreechemistry.chemical_compoundHorticultureGeographyfoodchemistryCapparis SpinosaAmplified fragment length polymorphismCaperAntioxidantQuercetinFlavor
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Chemical, Antioxidant and Biological Studies of Brassica incana subsp. raimondoi (Brassicaceae) Leaf Extract

2023

Brassica incana subsp. raimondoi is an endemic taxon present in a restricted area located on steep limestone cliffs at an altitude of about 500 m a.s.l. in eastern Sicily. In this research, for the first time, studies on the phytochemical profile, the antioxidant properties in cell-free and cell-based systems, the cytotoxicity on normal and cancer cells by 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay, and on Artemia salina Leach, were performed. The total phenolic, flavonoid, and condensed tannin contents of the leaf hydroalcoholic extract were spectrophotometrically determined. Ultra-performance liquid chromatography—tandem mass spectrometer (UPLC-MS/MS) analysi…

H2O2Pharmaceutical SciencecabbageHPLC/DADAnalytical ChemistryDrug Discoverybotanicalsoxidative stressSettore BIO/15 - Biologia Farmaceutica<i>Artemia salina</i> LeachPhysical and Theoretical ChemistrypolyphenolsArtemia salina Leachnutraceuticalsoxidative streH<sub>2</sub>O<sub>2</sub>Settore BIO/02 - Botanica SistematicaOrganic ChemistrycarotenoidsROSH2 O2carotenoidbotanicalpolyphenolcabbagesUPLC-MS/MSChemistry (miscellaneous)Molecular MedicinenutraceuticalMolecules
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Fast simultaneous determination of prominent polyphenols in vegetables and fruits by reversed phase liquid chromatography using a fused-core column

2015

A reversed-phase high-performance liquid chromatography method with photodiode array detection has been developed enabling the joint determination of 17 prominent flavonoids and phenolic acids in vegetables and fruits. A multi-segmented gradient program using a fused-core column for the separation of several phenolic classes (phenolic acids and flavonoids) has been optimised. The influence of extraction conditions (sample freeze-drying, ultrasound extraction, solvent composition and extraction time) has been also optimised using response surface methodology with tomato samples as a model. Complete recoveries (76-108%) were obtained for the phenolic compounds present in tomato. The developed…

HPLC-DADAnalytical ChemistryFused corePhenolsResponse surface methodologyLimit of DetectionVegetablesResponse surface methodologyChromatography High Pressure LiquidFlavonoidsDetection limitChromatography Reverse-PhaseChromatographyChemistryExtraction (chemistry)Polyphenolsfood and beveragesGeneral MedicineReversed-phase chromatographyRepeatabilityGENETICAFunctional qualityPolyphenolFoodFruitUltrasound-assisted extractionResponse Surface MethodologyColumn (botany)Food Science
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