Search results for "Pounds"

showing 10 items of 3374 documents

Low‐Valent Germanylidene Anions: Efficient Single‐Site Nucleophiles for Activation of Small Molecules

2021

Abstract Rare mononuclear and helical chain low‐valent germanylidene anions supported by cyclic (alkyl)(amino)carbene and hypermetallyl ligands were synthesised by stepwise reduction from corresponding germylene precursors via stable and isolable germanium radicals. The electronic structures of the anions can be described with ylidene and ylidone resonance forms with the Ge−C π‐electrons capable of binding even weak electrophiles. The germanylidene anions reacted with CO2 to give μ‐CO2‐κC:κO complexes, a rare coordination mode for low‐valent germanium and inaccessible for the related neutral germylones. These results implicate low‐valent germanylidene anions as efficient single‐site nucleop…

small molecule activationkemialliset yhdisteetdonor-acceptor systemsRadical010402 general chemistry01 natural sciencesMedicinal chemistryCatalysischemistry.chemical_compoundsub-valent compoundsNucleophilemain group elementsAlkylchemistry.chemical_classificationkemialliset reaktiot010405 organic chemistryChemistryCommunicationOrganic ChemistrymolekyylitGeneral ChemistryResonance (chemistry)Small moleculeCommunications0104 chemical sciences3. Good healthgermaniumaktivointiMain group elementElectrophileCarbenevalenssi (kemia)Chemistry – A European Journal
researchProduct

Implication of pyoverdines in the interactions of fluorescent pseudomonads with soil microflora and plant in the rhizosphere

2008

International audience

soil microflorarelation sol plante atmosphereplant root[SDV.BDD] Life Sciences [q-bio]/Development Biologyrhizodeposition[SDV.BDD]Life Sciences [q-bio]/Development Biologyorganic compoundsComputingMilieux_MISCELLANEOUSmicrobial grouwth
researchProduct

Evaluation of the Behavior of Phenolic Compounds and Steviol Glycosides of Sonicated Strawberry Juice Sweetened with Stevia (Stevia rebaudiana Berton…

2019

In this study, the influence of stevia addition and sonication processing parameters on the phenolic content and profile as well as the steviol glycosides of strawberry juice-based samples was investigated. For this purpose, three matrices&mdash

sonicationSonicationgreen stevia powder ; strawberry juice ; antioxidant compounds ; steviol glycosides ; sonicationPharmaceutical ScienceSteviol01 natural sciencesFragariaArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryantioxidant compoundsGlucosidesPhenolsDrug DiscoveryFood scienceSteviosidePhysical and Theoretical Chemistrysteviol glycosidesstrawberry juiceChromatography High Pressure Liquidchemistry.chemical_classificationFlavonoidsbiologyPlant Extracts010401 analytical chemistryOrganic ChemistryGlycoside04 agricultural and veterinary sciencesSweetnessgreen stevia powderbiology.organism_classification040401 food scienceStevia0104 chemical sciencesStevia rebaudianachemistryChemistry (miscellaneous)Molecular MedicineKaempferolDiterpenes KauraneMolecules
researchProduct

A Theoretical and Experimental Investigation of the Spectroscopic Properties of a DNA-Intercalator Salphen-Type ZnIIComplex

2014

The photophysical and DNA-binding properties of the cationic zinc(II) complex of 5-triethylammonium methyl salicylidene ortho-phenylenediiminato (ZnL 2 + ) were investi- gated by a combination of experimental and theoretical methods. DFT calculations were performed on both the ground and the first excited states of ZnL 2 + and on its possi- ble mono- and dioxidation products, both in vacuo and in selected solvents mimicked by the polarizable continuum model. Comparison of the calculated absorption and fluores- cence transitions with the corresponding experimental data led to the conclusion that visible light induces a two-elec- tron photooxidation process located on the phenylenediimi- nato…

spectroscopyNO ligandStereochemistryIntercalation (chemistry)Ionic bondingmetal complex Fluorescence spectroscopy DNA recognition metal complexes organometallics complex formation DNA binding drugs fluorescence spectroscopy equilibrium constants reaction mechanisms nucleic acids affinity binding mode thermodynamics speciationmetal complexesbinding modePhenylenediaminesPolarizable continuum modelCatalysisdrugsmetal complexthermodynamicsintercalationcomplex formationOrganometallic CompoundsA-DNADNA bindingFluorescence spectroscopyDNA recognitionphotochemistryLigandChemistrySpectrum AnalysisphotooxidationOrganic ChemistryCationic polymerizationequilibrium constantsGeneral Chemistrydensity functional calculationFluorescenceZincCrystallographyreaction mechanismsnucleic acidsspeciationSettore CHIM/03 - Chimica Generale E InorganicaExcited stateaffinityfluorescenceorganometallics
researchProduct

Realization of time-resolved two-vacuum-ultraviolet-photon ionization

2009

International audience; Ultrafast dynamics of excited molecules is studied through time-resolved two-vacuum-ultraviolet (vuv)- photon ionization using a nonlinear volume autocorrelator unit. The two-vuv-photon process is induced by the intense fifth harmonic radiation of a femtosecond Ti:sapphire laser. In a proof-of-principle experiment, ultrafast dynamics of excited ethylene and oxygen molecules are investigated. Molecular decay times are deduced by comparing the experimental data with the results of a numerical model that accounts for the spatial and temporal characteristics of the harmonic field. The present experiments pave a convenient way for time domain investigations in the vuv-xuv s…

spectroscopyattosecondPhoton[ PHYS.PHYS.PHYS-ATOM-PH ] Physics [physics]/Physics [physics]/Atomic Physics [physics.atom-ph]Physics::Opticsphotoionisationnm01 natural sciences7. Clean energyAtmospheric-pressure laser ionization010309 opticsFrequency conversionIonizationhigher order harmonic generation0103 physical sciencesPhysics::Atomic and Molecular Clustersethylenemoleculestwo-photon processesPhysics::Chemical Physics010306 general physicsUltrafast dynamicsPhysics[PHYS.PHYS.PHYS-ATOM-PH]Physics [physics]/Physics [physics]/Atomic Physics [physics.atom-ph]photodissociationdynamicsVUVAtomic and Molecular Physics and Opticslaser-pulsesVacuum ultravioletExtreme ultravioletmolecule-photon collisionsXUX32.80.Rm 42.65.Re 42.65.KyHHGAtomic physicsultrafast internal-conversionorganic compoundsphysicsRealization (systems)oxygen
researchProduct

Design Scheme of New Tetragonal Heusler Compounds for Spin-Transfer Torque Applications and its Experimental Realization

2012

Band Jahn-Teller type structural instabilities of cubic Mn(2)YZ Heusler compounds causing tetragonal distortions can be predicted by ab initio band-structure calculations. This allows for identification of new Heusler materials with tunable magnetic and structural properties that can satisfy the demands for spintronic applications, such as in spin-transfer torque-based devices.

spintronics010302 applied physicsMaterials scienceCondensed matter physicsSpintronicsMechanical EngineeringAb initioSpin-transfer torqueNanotechnology02 engineering and technology021001 nanoscience & nanotechnology01 natural sciencesCommunicationsspin-transfer torquesCondensed Matter::Materials ScienceTetragonal crystal systemMechanics of Materials0103 physical sciencesTorqueCondensed Matter::Strongly Correlated ElectronsGeneral Materials Sciencemagnetic properties0210 nano-technologyHeusler compoundsRealization (systems)Advanced Materials
researchProduct

DESIGN OF SF3B1 SUBUNIT MODULATORS OF THE SF3B SPLICEOSOME COMPLEX

2022

The subject of this dissertation is the search for new therapeutic strategies for pancreatic cancer and aims to implement a Drug Discovery process for the rational design and synthesis of molecules active in the modulation of pathways related to the regulation of pre-mRNA splicing process. This research project is the result of a joint PhD between the University of Palermo, Italy, and the Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands. It integrates complementary skills in pharmaceutical chemistry and translational cancer research with a special focus on the rational design of new anticancer compounds potentially active on SF3B1 (Splicing Factor 3B …

splicing4]thiadiazole compoundsdrug resistancehuman equilibrative nucleoside transporter-13mesotheliomaSF3B1gemcitabinepancreatic ductal adenocarcinoma1-b][1SF3B1 splicing imidazo[21-b][134]thiadiazole compounds pancreatic ductal adenocarcinoma gemcitabine human equilibrative nucleoside transporter-1 drug resistance mesotheliomaimidazo[2
researchProduct

Steroidal supramolecular metallogels

2020

The review deals with an expanding number of steroidal compounds that are capable of forming a metallogel providing a multitude of novel materials rich in their properties. The future of steroidal metallogels holds a myriad of potential applications as new intelligent materials. Detection of potentially harmful compounds without expensive instrumentation, entrapment of environmentally hazardous substances, and sensitive and selective nanomaterials represent only a few of these potential applications. This article reviews the design, synthesis, characterization, and applications of steroidal metallogels. peerReviewed

steroidal metallogelsMaterials sciencesteroidal compoundssupramolekulaarinen kemiaSupramolecular chemistryNanotechnologyGeneral ChemistryInstrumentation (computer programming)metallogelsChemical Society Reviews
researchProduct

Titanocene Selenide Sulfides Revisited: Formation, Stabilities, and NMR Spectroscopic Properties

2019

[TiCp2S5] (phase A), [TiCp2Se5] (phase F), and five solid solutions of mixed titanocene selenide sulfides [TiCp2SexS5−x] (Cp = C5H5−) with the initial Se:S ranging from 1:4 to 4:1 (phases B–E) were prepared by reduction of elemental sulfur or selenium or their mixtures by lithium triethylhydridoborate in thf followed by the treatment with titanocene dichloride [TiCp2Cl2]. Their 77Se and 13C NMR spectra were recorded from the CS2 solution. The definite assignment of the 77Se NMR spectra was based on the PBE0/def2-TZVPP calculations of the 77Se chemical shifts and is supported by 13C NMR spectra of the samples. The following complexes in varying ratios were identified in the CS2 solutions of …

sulfidit77Se-NMR spectroscopyPharmaceutical ScienceCrystal structureSulfidesorganometalliyhdisteet010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Seleniumcrystal structureschemistry.chemical_compoundChalcogenlcsh:Organic chemistrytitanocene selenide sulfidesSelenide0103 physical sciencesDrug DiscoveryOrganometallic CompoundsCarbon-13 Magnetic Resonance SpectroscopyNMR-spektroskopiaPhysical and Theoretical Chemistryta116DLPNO-CCSD(T) calculations13C-NMR spectroscopyCrystallographyMolecular Structure010304 chemical physics<sup>13</sup>C-NMR spectroscopyChemistryChemical shiftOrganic ChemistryTitanocene dichlorideCarbon-13 NMRkiteetStandard enthalpy of formation0104 chemical sciencesNMR spectra databasetitaani<sup>77</sup>Se-NMR spectroscopyChemistry (miscellaneous)Carbon DisulfideseleeniQuantum TheoryMolecular MedicinePhysical chemistryMolecules
researchProduct

Determination of glyphosate and its metabolite aminomethylphosphonic acid in fruit juices using supported-liquid membrane preconcentration method wit…

2005

Abstract The application of supported-liquid membrane (SLM) technique for effective extraction of N -(phosphonomethyl)glycine (glyphosate) and its primary metabolite aminomethylphosphonic acid (AMPA) from juices (orange, grapefruit, apple and blackcurrant) in combination with HPLC-UV detection after derivatization with p -toluenesulphonyl chloride (TsCl) is presented. The influence of various parameters such as the composition of acceptor phase, flow-rate, concentration of analytes, on the performance of extraction procedure, was studied. It was shown that by appropriate manipulation of SLM parameters the level of detection could be significantly improved. The influence of SLM conditions on…

supported-liquid membrane extractionMetaboliteGlycineOrganophosphonatesTetrazolesaminomethylphosphonic acidfruit juiceBiochemistryHigh-performance liquid chromatographyChlorideAnalytical ChemistryBeveragesTosyl Compoundschemistry.chemical_compoundglyphosatemedicineSample preparationAminomethylphosphonic acidDerivatizationChromatography High Pressure LiquidChromatographyOrganic ChemistryPrimary metaboliteMembranes ArtificialIsoxazolespesticidesGeneral MedicinechemistryFruitGlyphosateCalibrationSpectrophotometry UltravioletHPLCmedicine.drugJournal of Chromatography A
researchProduct