Search results for "Pressure"

showing 10 items of 4493 documents

Cardiovascular effects of the methanol and dichloromethanol extracts fromTeucrium flavum L.

1998

The effects on arterial blood pressure and heart rate of the methanol and dichloromethanol extracts from Teucrium flavumL. were analysed in urethane anaesthetized rats. Mean arterial blood pressure was significantly reduced by the i.v. administration of both extracts to normotensive rats. The methanol extract also induced a decrease in the heart rate, while the dichloromethanol extract lacked any effect on this parameter. © 1998 John Wiley & Sons, Ltd.

PharmacologyFolk medicinebiologyTraditional medicinebusiness.industryHemodynamicsPharmacognosybiology.organism_classificationTeucrium flavumTeucriumchemistry.chemical_compoundBlood pressurechemistryHeart rateMedicineMethanolbusinessPhytotherapy Research
researchProduct

Die Wirkung von Thiopental-Natrium und Pentobarbital-Natrium auf die Nierengef��e von M�usen

1957

The action of intravenous injections of pentobarbital and of thiopental on the blood pressure and on the vascular tone in the cortex of the kidney has been studied in albino mice. Pentobarbital caused a pronounced decrease of the filling of blood vessels in the cortex of kidneys together with a long-lasting anaesthesia and a long lasting fall of blood pressure. Thiopental, on the other hand, was less effective on the filling of blood vessels, while its narcotic effect was small and the fall of blood pressure less pronounced. The results indicate that both substances increased the vascular tone in the cortex of the kidney.

PharmacologyLong lastingKidneyPentobarbitalNarcoticbusiness.industrymedicine.medical_treatmentPharmacology toxicologyGeneral MedicineVascular tonemedicine.anatomical_structureBlood pressureAnesthesiaCortex (anatomy)medicinebusinessmedicine.drugNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
researchProduct

Quinol sulphate, a new conjugate of phenol in goldfish.

1983

1. Metabolism of phenol in goldfish yielded the known phenyl conjugates in fish--phenyl sulphate and phenyl glucuronide. Additionally, quinol sulphate, a new conjugate of phenol in fish, was detected.

PharmacologyPhenolChemistryHealth Toxicology and MutagenesisCyprinidaemacromolecular substancesGeneral MedicineMetabolismToxicologyBiochemistryHydroquinoneschemistry.chemical_compoundPhenolsGoldfishOrganic chemistryFish <Actinopterygii>PhenolAnimalssense organsChromatography Thin LayerGlucuronideChromatography High Pressure LiquidConjugateXenobiotica; the fate of foreign compounds in biological systems
researchProduct

Metabolism of phenol in the terrestrial snail Cepaea nemoralis L

1992

1. The metabolism of phenol in the terrestrial snail Cepaea nemoralis was studied after injection into the haemocoel of the dorsolateral foot region. 2. Excreted metabolites, and metabolites extracted from the body, were analysed by h.p.l.c. In addition to phenyl beta-D-glucoside, arbutine (quinol beta-D-glucoside), a new conjugate of phenol, was detected.

PharmacologyPhenolbiologybeta-GlucosidaseHealth Toxicology and MutagenesisSnailsGeneral MedicineSnailMetabolismToxicologybiology.organism_classificationBiochemistrychemistry.chemical_compoundPhenolschemistrybiology.animalGastropodaBotanyCepaeaAnimalsPhenolMolluscaChromatography High Pressure LiquidXenobiotica
researchProduct

Comparative enantioseparation of planar chiral ferrocenes on polysaccharide‐based chiral stationary phases

2022

Planar chiral ferrocenes are well-known compounds that have attracted interest for application in synthesis, catalysis, material science, and medicinal chemistry for several decades. In spite of the fact that asymmetric synthesis procedures for obtaining enantiomerically enriched ferrocenes are available, sometimes, the accessible enantiomeric excess of the chiral products is unsatisfactory. In such cases and for resolution of racemic planar chiral ferrocenes, enantioselective high-performance liquid chromatography (HPLC) on polysaccharide-based chiral stationary phases (CSPs) has been used in quite a few literature articles. However, although moderate/high enantioselectivities have been ob…

PharmacologyPlanar chiralityMetallocenesElectrostatic potentialelectrostatic potential; enantioseparation; ferrocenes; planar chirality; polysaccharide-based chiral stationary phasesOrganic ChemistryStereoisomerismQuímica analíticaSettore CHIM/06 - Chimica OrganicaPolysaccharide-based chiral stationary phasesCatalysisEnantioseparationAnalytical ChemistryPolysaccharidesDrug DiscoverySettore CHIM/01 - Chimica AnaliticaAmyloseFerrocenesChromatography High Pressure LiquidSpectroscopyChirality
researchProduct

Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India

2000

'Darakchasava' is a well known Indian herbal preparation of which the main ingredient is Vitis vinifera L. This 'ayurvedic' medicine is prescribed as a cardiotonic and also given for other disorders. HPLC analysis of this age old formulation revealed the presence of polyphenols like resveratrol and pterostilbene. These phenolic compounds are now known as antioxidants, cancer chemopreventive agents, and also known to reduce mortality from coronary heart disease by increasing high density lipoproteins like cholesterol and inhibiting platelet aggregation (Soleas, J.S., Diamandis, E.P., Goldberg, D.M., 1997. Resveratrol: a molecule whose time has come? and gone? Clin. Biochem. 30 (2), 91-113). …

PharmacologyPterostilbeneTraditional medicinePlant ExtractsCholesterolIndiafood and beveragesPharmacognosyResveratrolAntineoplastic Agents PhytogenicAntioxidantsMedicine Ayurvedicchemistry.chemical_compoundIngredientPhenolschemistryResveratrolPolyphenolStilbenesDrug DiscoveryHypoglycemic AgentsPlatelet aggregation inhibitorVitis viniferaChromatography High Pressure LiquidPlatelet Aggregation InhibitorsJournal of Ethnopharmacology
researchProduct

Effects on Arterial Blood Pressure of Methanol and Dichloromethanol Extracts fromJuniperus oxycedrus L.

1997

The present study analysed the effect of the methanol and dichloromethanol extracts from Juniperus oxycedrus on arterial blood pressure in anaesthetized rats. The arterial blood pressure of normotensive rats was significantly reduced by the i.v. administration of both extracts. The hypotensive effect of these extracts was independent of the adrenergic system. These results may explain the vasorelaxing actions observed in other Juniperus species.

PharmacologyTraditional medicinebiologybusiness.industryHypotensive drugAdrenergicHemodynamicsBiological activityPharmacognosybiology.organism_classificationchemistry.chemical_compoundBlood pressurechemistryMedicineMethanolbusinessJuniperus oxycedrusPhytotherapy Research
researchProduct

Effects on Arterial Blood Pressure of the Methanol and Dichloromethanol Extracts from Schinus molle L. in Rats

1996

The effects on arterial blood pressure of the methanol and dichloromethanol extracts from Schinus molle L. were analysed in urethane anaesthetized rats. In normotensive rats, the mean arterial blood pressure was significantly reduced by the i.v. administration of both extracts. The dichloromethanol extract inhibited the effects of noradrenaline on arterial blood pressure in the anaesthetized rat and it reduced the maximal contractile effect (Emax) induced by noradrenaline on rat vas deferens in the organ bath. However, the methanol extract did not modify the effects of noradrenaline in the evaluated tests.

PharmacologyTraditional medicinebiologybusiness.industryVas deferensHemodynamicsBiological activityPharmacologyPharmacognosybiology.organism_classificationSchinus molleNorepinephrine (medication)chemistry.chemical_compoundmedicine.anatomical_structureBlood pressurechemistrymedicineMethanolbusinessmedicine.drugPhytotherapy Research
researchProduct

Effects on arterial blood pressure of the methanol extracts from differentTeucriumspecies

1997

Methanol extracts of the leaves and stems of two Teucrium species (T. pumillum L. and T. buxifolium L.) have been tested for their effects on resting arterial blood pressure. Both T. pumillum L. and T. buxifolium L. extracts reduced mean arterial blood pressure in a dose dependent manner when administered i.v. to urethane anaesthetized normotensive rats. © 1997 John Wiley & Sons, Ltd.

PharmacologybiologyTraditional medicinebusiness.industryHypotensive drugDose dependencePharmacognosybiology.organism_classificationTeucriumchemistry.chemical_compoundBlood pressurechemistryTeucrium pumilumMedicineLamiaceaeMethanolbusinessPhytotherapy Research
researchProduct

Editorial: Management of Elevated Heart Rate in Essential Hypertension: Pathophysiological Insights and Therapeutic Approach.

2017

Pharmacologybusiness.industryPhysical activityPhysical activityDisease ManagementBlood PressureBioinformaticsEssential hypertensionmedicine.diseasePathophysiologyElevated heart rateTherapeutic approachHeart RateDrug DiscoveryMedicineAnimalsHumansEssential HypertensionbusinessCurrent pharmaceutical design
researchProduct