Search results for "Prevalence"
showing 10 items of 1793 documents
Comparison of Claudin 18.2 expression in primary tumors and lymph node metastases in Japanese patients with gastric adenocarcinoma.
2019
CLDN18.2 expression is highly prevalent in Japanese patients with gastric cancer, making it a targetable alteration, and supporting development of zolbetuximab as a therapeutic agent for this patient population.
Prognostic role of tumour multifocality in renal cell carcinoma.
2012
Study Type - Therapy (multi-centre cohort) Level of Evidence3b What's known on the subject? and What does the study add? In RCC about 5% of the patients presented multifocal disease. Prevalence of tumour multifocality was associated with a higher percentage of symptomatic RCC, higher pathological TNM stages, higher tumour grade and higher prevalence of tumour necrosis. Although in univariable analysis multifocal tumours had lower probability of CSS, tumour multifocality did not retain an independent predictive role in multivariable analysis. Patient age at surgery, gender, mode of presentation, pathological N stage and presence of metastases were independent predictors of CSS in multivariab…
Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of infection in intensive care unit study
2011
Objectives: To provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients and compare Candida with bacterial bloodstream infection. Design: A retrospective analysis of the Extended Prevalence of Infection in the ICU Study (EPIC II). Demographic, physiological, infection-related and therapeutic data were collected. Patients were grouped as having Candida, Gram-positive, Gram-negative, and combined Candida/bacterial bloodstream infection. Outcome data were assessed at intensive care unit and hospital discharge. Setting: EPIC II included 1265 intensive care units in 76 countries. Patients: Patients in partic…
Diagnosi di enteriti infettive di origine virale nel cane
2013
Canine Viral Enteritis are widespread in farms and kennels. Responsible viruses are Parvovirus (CPV), Coronavirus (CCoV), Rotavirus (CRV) and Distemper Virus (CDV). Aim of this study was to assess their prevalence in Sicily and to characterize the strains isolated during 2009-2012. For this purpose, samples (stools, rectal swabs, intestine, liver, spleen, heart, lung, brain) collected from dogs were analyzed by PCR, RT-PCR and Real Time RT-PCR. Positive samples were processed for virus isolation on cell lines. Viruses isolated were analyzed by RFLP and sequencing for molecular characterization. Results show an high prevalence of CPV infection in dogs, followed by CCoV, CRV and CDV. CPV prev…
DMFT indekss un kariesa izplatība Latvijas Universitātes studentu zobārstniecības klīnikas pacientiem
2022
Mutes veselībai ir ļoti nozīmīgs iedzīvotāju labklājības faktors. Slikta mutes dobuma veselība var būt par iemeslu sāpēm, zobu zaudējumam, funkciju zudumumam un pazeminātai pašcieņai. Zobu kariess ir viena no divām visbiežāk sastopamajām mutes dobuma saslimšanām un zobu zaudējuma iemesliem. Epidemioloģiskie pētījumi, izmantojot dažādus starptautiski pieņemtus indeksus, lēš, ka globāli neārstēts kariess pastāvīgo zobos ir 2,3 miljardiem cilvēku un neārstēts kariess piena zobos - 532 miljoniem bērnu. Taču pētījumu pieaugušajiem ir daudz mazāk nekā bērniem, kas arī pamato darba mērķi - analizēt DMFT indeksu un kariesa izplatību pieaugušiem pacientiem, kuri apmeklē Latvijas Universitātes Studen…
Polyvascular subclinical atherosclerosis in familial hypercholesterolemia: The role of cholesterol burden and gender
2019
International audience; BACKGROUND AND AIM:Heterozygous familial hypercholesterolemia (HeFH) is a genetic disease characterized by a heterogeneous phenotype. The assessment of cardiovascular (CV) risk is challenging for HeFH. Cholesterol burden (CB) allows to estimate the lifelong exposure to high levels of cholesterol. The aim of this study was to analyze the distribution of subclinical atherosclerosis and the relationship between atherosclerosis and the CB in a sample of HeFH patients, focusing on sex-related differences.METHODS AND RESULTS:154 asymptomatic HeFH subjects underwent coronary-artery-calcium score (CACs) and Doppler ultrasound of carotid and femoral arteries. Yearly lipid pro…
Renal function and carotid atherosclerosis in adults with no known kidney disease
2017
Abstract Background and aims A high prevalence of atherosclerotic lesions characterizes patients with chronic kidney disease, though there is little data on the relationship between kidney function and atherosclerotic changes in the healthy population or in people with no known renal impairment. The aim of our study was to analyze, in a comprehensive general population with no known kidney disease, the relationship between renal function and subclinical carotid atherosclerotic damage. Methods and results A general real-life population of 611 participants (233 males and 378 females; age ≥18 years) with no known kidney failure was selected for the study. The glomerular filtration rate (GFR) w…
Liraglutide improves metabolic parameters and carotid intima-media thickness in diabetic patients with the metabolic syndrome: an 18-month prospectiv…
2016
Abstract Background Liraglutide, a GLP-1 analogue, exerts several beneficial non-glycemic effects in patients with type-2 diabetes (T2DM), such as those on body weight, blood pressure, plasma lipids and inflammation markers. However, the effects of liraglutide on cardiovascular (CV) risk markers in subjects with the metabolic syndrome (MetS) are still largely unknown. We herein explored its effects on various cardio-metabolic risk markers of the MetS in subjects with T2DM. Methods We performed an 18-month prospective, real-world study. All subjects had T2DM and the MetS based on the AHA/NHLBI criteria. Subjects with a history of a major CV event were excluded. One hundred-twenty-one subject…
Carotid atherosclerosis and chronic hepatitis C: A prospective study of risk associations
2011
BACKGROUND AND AIMS: There are contrasting results in studies of cardiovascular risk in patients with genotype 1 chronic hepatitis C (G1 CHC). We evaluated the prevalence of carotid atherosclerosis compared with a control population in order to assess the potential association between atherosclerosis, host and viral factors, and liver histological features. MATERIALS AND METHODS: One hundred seventy-four consecutive biopsy-proven G1 CHC patients were evaluated by anthropometric and metabolic measurements. One hundred seventy-four patients attending an outpatient cardiology unit were used as controls. Intima-media thickness (IMT) and carotid plaques, defined as focal thickening of > 1.3 mm a…
Carotid atherosclerosis in hypercholesterolemic patients: Relationship with cardiovascular events
2001
Background and Aim: Extracranial cerebrovascular atherosclerosis is a common feature of hypercholesterolemia and carotid lesions are good predictors of cardiovascular events in the general population. Factors associated with the carotid damage of hypercholesterolemic patients and their relationships with the occurrence of clinical events are investigated in this study. Methods and Results: One hundred and seventeen cardiovascular event-free hypercholesterolemic subjects underwent a complete clinical examination to look for additional risk factors. A blood sample was collected for lipoprotein determination and an ultrasound high resolution B-mode imaging examination of the common carotid art…