Search results for "Printing"

showing 10 items of 532 documents

Determination of non-steroidal anti-inflammatory drugs in water and urine using selective molecular imprinted polymer extraction and liquid chromatog…

2016

Abstract A selective solid-phase extraction was employed for the improvement of the determination of non-steroidal anti-inflammatory drugs (NSAIDs) in continental water and urine samples. Ketoprofen, naproxen, diclofenac, and ibuprofen were selected as target analytes due to they are the most frequently administered and consumed NSAIDs. These compounds were extracted using molecular imprinted polymers and determined by liquid chromatography with diode array (DAD), and tandem-mass spectrometry (MS–MS) detectors. Performance of DAD and MS–MS detectors was evaluated throughout this study. The obtained limits of quantification, after a 50-fold preconcentration solid-phase extraction, varied fro…

KetoprofenAnalyteNaproxenPolymersClinical BiochemistryPharmaceutical Science02 engineering and technologyUrineMass spectrometry01 natural sciencesAnalytical ChemistryMolecular ImprintingTandem Mass SpectrometryDrug DiscoverymedicineSpectroscopyChromatographyChemistryAnti-Inflammatory Agents Non-Steroidal010401 analytical chemistryExtraction (chemistry)Molecularly imprinted polymerWater021001 nanoscience & nanotechnologyIbuprofen0104 chemical sciences0210 nano-technologyWater Pollutants ChemicalChromatography Liquidmedicine.drugJournal of Pharmaceutical and Biomedical Analysis
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Knowledge formalization and recommendation in computational design synthesis for 4D printing

2022

Coined in 2013, 4D printing is considered as a promising technology that combines additive manufacturing (AM) processes and smart materials (SMs). Through this technology objects can change over time in terms of functionalities, shape, or properties under the effect of energy stimulation. Although AM processes allow shape, hierarchical, functional, and materials complexities to the 3D objects, the conjunction with SMs provides much more freedom in designing adaptive/transformative structures. Over the last decade, a growing body of research with ad hoc proofs-of-concept have been proposed at the physical level (i.e., by using different AM processes with commercial or customized 3D printers …

KnowledgeRecommandationOntology[SPI.OTHER] Engineering Sciences [physics]/OtherComputational design synthesisOntologie4D printingRecommendationConnaissanceConceptionImpression 4D
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BIO Bragg gratings on microfibers for label-free biosensing

2021

[EN] Discovering nanoscale phenomena to sense biorecognition events introduces new perspectives to exploit nano science and nanotechnology for bioanalytical purposes. Here we present Bio Bragg Gratings (BBGs), a novel biosensing approach that consists of diffractive structures of protein bioreceptors patterned on the surface of optical waveguides, and tailored to transduce the magnitude of biorecognition assays into the intensity of single peaks in the reflection spectrum. This work addresses the design, fabrication, and optimization of this system by both theoretical and experimental studies to explore the fundamental physicochemical parameters involved. Functional biomolecular gratings ar…

Label free biosensingbusiness.product_categoryMaterials scienceBiomedical EngineeringBiophysicsdiffractionNanotechnology02 engineering and technologyBiosensing TechniquesNon-specific bindingbiosensor01 natural sciencesSignalMultiplexinglabel free:FÍSICA [UNESCO]QUIMICA ANALITICATEORIA DE LA SEÑAL Y COMUNICACIONESMicrofiberElectrochemistryHumansNanotechnologyoptical microfiberimmunoassayImmunoassayQUIMICA INORGANICA010401 analytical chemistrynon-specific bindingUNESCO::FÍSICAGeneral Medicine021001 nanoscience & nanotechnology0104 chemical sciencesReflection spectrumMicrocontact printingNanoscale PhenomenaLabel-free0210 nano-technologybusinessDiffractionOptical microfiberBiosensorBiosensorBiotechnology
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A quantitative approach for assessing significant improvements in elite sprint performance: Has IGF-1 entered the arena?

2012

The introduction of doping substances and methods in sports triggers noticeable effects on physical performance in metric sports. Here, we use time series analysis to investigate the recent development in male and female elite sprinting performance. Time series displaying the average of the world's top 20 athletes were analyzed employing polynomial spline functions and moving averages. Outstanding changes in performance over time were statistically analyzed by Welch's t-test and by Cohen's measurements of effect. For validation we exemplarily show that our analysis is capable of indicating the effect of the introduction of in- and out-of-competition doping testing on women's shot put as wel…

Large effect sizeSPRINTING PERFORMANCEPharmaceutical ScienceShot putAnabolic-Androgenic SteroidsAnalytical ChemistrySprintPhysical performanceStatisticsEnvironmental Chemistryhuman activitiesSpectroscopySimulationMathematicsDrug Testing and Analysis
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Guided hierarchical co-assembly of soft patchy nanoparticles.

2013

Different polymers can be used in combination to produce coexisting nanoparticles of different symmetry and tailored to co-assemble into well-ordered binary and ternary hierarchical structures. There is considerable practical interest in developing the tools to fabricate multicomponent artificial systems that mimic the hierarchical ordering seen in the natural world — complex biomaterials can be assembled from the simple but precisely defined molecular building blocks. Andre Groschel and colleagues have developed a bottom-up approach that's a step in that direction. Previously they designed simple linear polymers that self-assemble in solution to produce monodisperse nanoparticles with well…

Length scaleMultidisciplinaryMaterials scienceMicrocontact printingMolecular self-assemblyParticleNanoparticleNanotechnologySelf-assemblyTernary operationSmart materialNature
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Genetic and Biochemical Analysis of PadR-padC Promoter Interactions during the Phenolic Acid Stress Response in Bacillus subtilis 168

2011

ABSTRACT Bacillus subtilis 168 is resistant to phenolic acids by expression of an inducible enzyme, the phenolic acid decarboxylase (PadC), that decarboxylates these acids into less toxic vinyl derivatives. In the phenolic acid stress response (PASR), the repressor of padC , PadR, is inactivated by these acids. Inactivation of PadR is followed by a strong expression of padC . To elucidate the functional interaction between PadR and the padC promoter, we performed (i) footprinting assays to identify the region protected by PadR, (ii) electrophoretic mobility shift assays (EMSAs) with a modified padC promoter protected region to determine the interacting sequences, and (iii) random mutagenesi…

Leucine zipperMutantRepressorElectrophoretic Mobility Shift AssayGenetics and Molecular BiologyBacillus subtilisBiologyMicrobiologyProtein Structure Secondary03 medical and health scienceschemistry.chemical_compoundBacterial ProteinsStress PhysiologicalBacillus subtilis 168Hydroxybenzoates[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPromoter Regions GeneticMolecular Biology030304 developmental biology2. Zero hungerchemistry.chemical_classification0303 health sciences030306 microbiologyMutagenesisPhenolic acidGene Expression Regulation Bacterialbiology.organism_classificationMolecular biologyFootprintingEnzymechemistryBiochemistryBacillus subtilisProtein Binding
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The Mulgandinnah Shear Zone; an Archean crustal scale strike-slip zone, eastern Pilbara, Western Australia

1998

Abstract A large part of the deformation in the Archean Pilbara granitoid-greenstone terrain is localized in relatively narrow shear zones. The Mulgandinnah shear zone (MSZ) is a major one of these, with a width up to 8 km, that can be followed for over 70 km along strike in the Shaw Batholith in the eastern Pilbara. It forms part of the Mulgandinnah Lineament, that can be traced to the Lalla Rookh Basin and the Carlindi Batholith in the north, giving it a total length of over 150 km. The MSZ contains both mylonites and ultramylonites, both of which have foliations that are subvertical to steeply dipping, with the ultramylonitic foliation overprinting the mylonitic foliation to form more lo…

LineationShear (geology)LineamentGeochemistry and PetrologyBatholithGeochemistryGeologyShear zoneStrike-slip tectonicsOverprintingGeologySeismologyMylonitePrecambrian Research
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Contexto editorial, cultural y socio-político de la edición príncipe de la «Historia de la doncella Teodor» (Toledo: Pedro Hagenbach, 1500-1501)

2021

The material analysis of the only surviving copy of the editio princeps of the Historia de la doncella Teodor allows us to date it back to the incunabula era and to attribute its printing to Pedro Hagenbach’s workshop. The close relationship amongst Hagenbach’s workshop, the reformist project of Archbishop Cisneros, and the interests of the Catholic Monarchs sets an editorial and cultural context that supports the adaptation of Teodor to the printing press. This work perfectly agreed with the thematic and ideological guidelines for the renewal of Christian customs and values. The forceful religious and intellectual imposition of the young and learned slave, turned into a “fijadalgo” in the …

Linguistics and LanguageHistoryLiterature and Literary TheoryArchbishopmedia_common.quotation_subjectCultural contextHistoria de la doncella TeodorContext (language use)Forced conversionLanguage and Linguisticslaw.inventionPrinting pressPoliticsPedro HagenbachClose relationshiplawPropaganda políticaIdeologyReyes CatólicosHumanitiesEdición príncipemedia_common
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The application of molecular imprinting technology to solid phase extraction

2001

In parallel to a long lasting search for universal multi-purpose sorbents, the area of solid phase extraction (SPE) is recently experiencing a rapid development of new types of tailor-made class specific or compound-specific sorbents which are designed to respond to the increasing demand for selectivity and efficiency in sample clean-up prior to quantification. An important issue here is the enrichment and clean-up of complex samples, such as environmental waters, sediments, biofluids and foodstuffs prior to detection. This because the analyte is often present in low concentration in a complex mixture of similar compounds and therefore needs to be isolated and enriched in order to be detect…

Long lastingAnalyteChromatographyChemistryOrganic ChemistryClinical BiochemistrySolid-phase microextractionBiochemistryAnalytical ChemistryAdsorptionSample preparationSolid phase extractionMolecular imprintingSelectivityChromatographia
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Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring

2019

Mothers transfer immune cells via breastfeeding to provide offspring with long-term protection from parasitic infection.

Long lastingCD4-Positive T-LymphocytesMaleCellular immunityOffspring[SDV]Life Sciences [q-bio]animal diseasesImmunologyAntibodies Helminthchemical and pharmacologic phenomenaReceptors Cell SurfaceBiology03 medical and health sciences0302 clinical medicineImmune systemTh2 CellsNursingImmunityPregnancymedicineHelminthsAnimalsLactationImprinting (psychology)Research Articles030304 developmental biologyStrongylida Infections0303 health sciencesPregnancyB-LymphocytesImmunity CellularMice Inbred BALB CMultidisciplinarySciAdv r-articlesbiochemical phenomena metabolism and nutritionmedicine.disease3. Good healthAnimals SucklingMice Inbred C57BLbacteriaFemaleNippostrongylusImmunity Maternally-Acquired030215 immunologyResearch ArticleScience Advances
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