Search results for "Process"
showing 10 items of 22310 documents
Magnetic resonance chondro-crassometry (MR CCM): a method for accurate determination of articular cartilage thickness?
1996
A method for the assessment of articular cartilage thickness based on MRI is presented and its accuracy and reproducibility tested. Six specimens of human patellae were imaged, using a fat-suppressed FLASH 3D sequence, and sectioned with a high-precision band saw. The regional distribution of articular cartilage thickness was determined from the MR images and from the anatomical sections (intervals of 0.5 mm). With image analysis 50-90% of the image points were found to lie within exactly the same thickness interval in corresponding patterns, and less than 17% deviated more than 0.5 mm. More than 85% of all pixels were reproducible with MRI after new positioning of the joint. No influence o…
Repeatability of patellar cartilage thickness patterns in the living, using a fat-suppressed magnetic resonance imaging sequence with short acquisiti…
1998
A fast, reproducible, and noninvasive method is required for quantifying cartilage thickness clinically and for studying the deformation of articular cartilage during and after mechanical loading in vivo. The objective of the current investigation was to test the repeatability of regional distribution patterns of patellar cartilage thickness in the living on the basis of a fat-suppressed magnetic resonance imaging sequence with a short acquisition time and three-dimensional digital data processing. The knees of eight healthy volunteers were transversally imaged with a fat-suppressed FLASH-3D (fast low angle shot) sequence (acquisition time: 4 minutes and 10 seconds). In each case, the joint…
Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging.
1997
Abstract Data on articular cartilage thickness in the living are important for the design of computer models, aimed at preoperatively assessing the effect of surgical procedures on joint contact and load transmission, and for the calculation of cartilage material properties from its deformational behavior as determined during arthroscopy. A non-invasive method for measuring cartilage thickness in living subjects is, however, not available. A technique based on magnetic resonance imaging has therefore been tested for assessing articular cartilage thickness throughout joint surfaces. The accuracy is determined by comparing cartilage thickness maps obtained from three patellar specimens with a…
Posttranslationally modified proteins as mediators of sustained intestinal inflammation.
2006
Oxidative and carbonyl stress leads to generation of N(epsilon)-carboxymethyllysine-modified proteins (CML-mps), which are known to bind the receptor for advanced glycation end products (RAGE) and induce nuclear factor (NF)-kappaB-dependent proinflammatory gene expression. To determine the impact of CML-mps in vivo, RAGE-dependent sustained NF-kappaB activation was studied in resection gut specimens from patients with inflammatory bowel disease. Inflamed gut biopsy tissue demonstrated a significant up-regulation of RAGE and increased NF-kappaB activation. Protein extracts from the inflamed zones, but not from noninflamed resection borders, caused perpetuated NF-kappaB activation in cultured…
The attentional blink demonstrates automatic deviance processing in vision.
2011
Rare deviations in serial visual stimulation are accompanied by an occipital N2 in the event-related potential [the visual mismatch negativity (vMMN)]. Recent research suggests that the vMMN reflects automatic processing of information on the sensory level as a basis for change detection. To directly test the hypothesis that the vMMN is independent from attention, a rapid-serial-visual-presentation paradigm was applied: Either 300 ms or 700 ms after the presentation of a target (T1) a rare position change was embedded in the stimulation which elicited a vMMN. In another condition participants had to detect a second target (T2) after T1: Importantly, within 300 ms after T1, T2 detection was …
Reduced interhemispheric structural connectivity between anterior cingulate cortices in borderline personality disorder
2008
Functional and structural alterations of the anterior cingulate cortex (ACC), a key region for emotional and cognitive processing, are associated with borderline personality disorder (BPD). However, the interhemispheric structural connectivity between the left and right ACC and between other prefrontal regions in this condition is unknown. We acquired diffusion-tensor imaging data from 20 healthy women and 19 women with BPD and comorbid attention-deficit hyperactivity disorder (ADHD). Interhemispheric structural connectivity between both sides of the ACC, dorsolateral prefrontal cortices and medial orbitofrontal cortices was assessed by a novel probabilistic diffusion tensor-based fiber tra…
Cognitive priming in sung and instrumental music: Activation of inferior frontal cortex
2006
Neural correlates of the processing of musical syntax-like structures have been investigated via expectancy violation due to musically unrelated (i.e., unexpected) events in musical contexts. Previous studies reported the implication of inferior frontal cortex in musical structure processing. However - due to the strong musical manipulations - activations might be explained by sensory deviance detection or repetition priming. Our present study investigated neural correlates of musical structure processing with subtle musical violations in a musical priming paradigm. Instrumental and sung sequences ended on related and less-related musical targets. The material controlled sensory priming com…
The Resilient Emotional Brain: A Scoping Review of the Medial Prefrontal Cortex and Limbic Structure and Function in Resilient Adults With a History …
2020
Childhood Maltreatment (CM) is one of the strongest predictors of adult mental illness, though not all adults with CM develop psychopathology. Here, we describe the structure and function of emotional brain regions that may contribute to resilient functioning after CM. We review studies that report medial prefrontal cortex (mPFC), amygdala and hippocampus (‘limbic regions’) structure, function, and/or connections, in resilient (i.e., adults reporting CM without psychopathology) vs. vulnerable (i.e., adults reporting CM with psychopathology), or healthy adults (adults without CM with no psychopatology). We find that resilient adults have larger hippocampal grey and white matter volume, and i…
Attachment anxiety and avoidance and perceptions of group climate: an actor-partner interdependence analysis.
2012
There is a lack of research examining group members’ attachment styles and group climate perceptions in the context of the attachment styles and group climate perceptions of the other group members. In the current study, the actor–partner interdependence model (APIM) was used to examine the relationships among (a) a group member’s attachment pattern, (b) the aggregated attachment patterns of the other group members, (c) a group member’s perceptions of the group’s climate, and (d) the aggregated group climate perceptions of the other group members. One hundred ten Italian graduate students in six 10-session interpersonal growth groups were studied. Group members filled out the Attachment Sty…
The association between physicians' exercise counseling and physical activity in patients with cancer: Which roles do patients' satisfaction and prev…
2020
Objectives The purpose of this study was to examine the association between physicians' exercise counseling and post-diagnosis physical activity (PA) in patients with cancer by investigating the mediating role of patients' satisfaction with exercise counseling as well as the moderating role of patients' previous PA. Methods The study sample consisted of 1002 people with cancer (503 breast, 265 prostate, and 234 colorectal cancer). Participants reported their pre- and post-diagnosis moderate-to-vigorous PA (MVPA) levels, indicated whether their physician had covered different steps of exercise counseling as defined by the 5A framework (Assess, Advise, Agree, Assist, and Arrange) and rated th…