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showing 10 items of 980 documents

Farmed Gilthead Sea Bream (Sparus aurata) by-Products Valorization: Viscera Oil ω-3 Enrichment by Short-Path Distillation and In Vitro Bioactivity Ev…

2021

This study shows a pilot scale protocol aimed to obtain an omega 3-enriched oil after the processing of farmed gilthead sea bream viscera (SBV)

Antioxidant030309 nutrition & dieteticsThiobarbituric acidFish farmingmedicine.medical_treatmentShort path distillationPharmaceutical SciencePilot ProjectsnutraceuticsAntioxidantsMice03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologySettore AGR/20 - Zoocolture3T3-L1 CellsFatty Acids Omega-3Drug DiscoveryAdipocytesTBARSmedicineAnimalsPeroxide valueFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaPharmacology Toxicology and Pharmaceutics (miscellaneous)by-productslcsh:QH301-705.5DistillationWaste Productschemistry.chemical_classification0303 health sciencesAdipogenesisomega-3 fatty acidsFatty acid04 agricultural and veterinary sciences040401 food scienceSea Breamfish oilsOxidative StressViscerachemistryaquaculturelcsh:Biology (General)BassPolyunsaturated fatty acidMarine Drugs
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Increase in stability and change in supramolecular structure of β-carotene through encapsulation into polylactic acid nanoparticles

2011

International audience; β-Carotene (BC) exhibits controversial antioxidant properties as it may act also as a prooxidant. Its stability toward oxidation depends on its dispersion form and can be increased through encapsulation. In this study, oxidation of BC from synthetic and natural origins was investigated after dispersion in Tween micelles or poly lactic acid (PLA) particles. Two oxidation systems were used: autooxidation and oxidation by xanthine oxidase-generated-reactive oxygen species. Results showed that synthetic BC formed nanometric negatively-charged particles in both Tween micelle and PLA systems, whereas the natural BC sample used was shown to be already pre-oxidised, forming …

Antioxidant030309 nutrition & dieteticsmedicine.medical_treatmentSupramolecular chemistryNanoparticleβ-CaroteneMicellePolylactic acidAnalytical Chemistry03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyPolylactic acidOxidationmedicineOrganic chemistry[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyXanthine oxidaseSupramolecular aggregation0303 health sciencesAutoxidationProoxidant04 agricultural and veterinary sciencesGeneral Medicine040401 food scienceLactic acidChemical engineeringchemistrySpectrophotometryEncapsulationParticle sizeOxidation productsFood Science
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Stability of carotenoid extracts of gấc (Momordica cochinchinensis) towards cooxidation — Protective effect of lycopene on β-carotene

2011

International audience; Momordica cochinchinensis, so-called gấc in Vietnam, is considered as a fruit with high nutritional potential. Its antioxidant property, due to a high concentration of carotenes (β-carotene and lycopene), is particularly estimated. In this study, we have investigated the degradation of carotene extracts obtained from gấc aril. These extracts were dispersed in the aqueous phase in Tween 80 micelles or were encapsulated into polylactic acid (PLA) particles. In both cases, carotenes were far less degraded than synthetic β-carotene. However, the degradation of lycopene was still rapid (around 1 mM lycopene degraded per hour), whereas β-carotene was almost not bleached. M…

AntioxidantMomordica cochinchinensismedicine.medical_treatmentIononeMicellePolylactic acid03 medical and health scienceschemistry.chemical_compoundLycopene0404 agricultural biotechnologyPolylactic acidGấcOxidationCarotene cleavage productsmedicineOrganic chemistry[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyXanthine oxidaseCaroteneCarotenoid030304 developmental biologychemistry.chemical_classification0303 health sciencesbiologyCarotene04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceLycopenechemistryEncapsulationAntioxidantIononeFood ScienceFood Research International
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Almond (Prunus dulcis cv. Casteltermini) Skin Confectionery By-Products: New Opportunity for the Development of a Functional Blackberry (Rubus ulmifo…

2021

This work proposes for the first time a model for reusing almond (Prunus dulcis cv. Casteltermini from Sicily, Southern Italy) skin to formulate a new functional blackberry (Rubus ulmifolius Schott) jam. For this purpose, blackberries were analysed fresh and as jam, traditionally prepared with a minimum fruit amount of 80%. Different percentages of almond skin (20, 15, and 10% w/w) were added to jam. The phytochemical profile of enriched jam was investigated by LC-ESI/LTQOrbitrap/MS analyses. Anthocyanins, hydrolysable tannins, and triterpenoids were identified in a blackberry extract, while proanthocyanidins, flavonoids, and oxylipins were identified in an almond extract. The n-hexane extr…

AntioxidantPhysiologyDPPHmedicine.medical_treatmentClinical BiochemistryRM1-950carbohydrate hydrolysing enzymesPrunus dulcis cv. Casteltermini skin01 natural sciencesBiochemistrySensory analysisArticlechemistry.chemical_compound0404 agricultural biotechnologylipasemedicineGC–MS<i>Prunus dulcis</i> cv. Casteltermini skinFood scienceBy-products; Carbohydrate hydrolysing enzymes; GC–MS; LC-ESI/LTQOrbitrap/ MS; Lipase; Prunus dulcis cv. Casteltermini skin; Rubus ulmifolius<i>Rubus ulmifolius</i>by-productsMolecular BiologyLC-ESI/LTQOrbitrap/MSABTSRubus ulmifoliusbiologyChemistryBy-products Carbohydrate hydrolysing enzymes GC–MS LC-ESI/LTQOrbitrap/ MS Lipase Prunus dulcis cv. Casteltermini skin Rubus ulmifoliusfungi010401 analytical chemistryfood and beveragesSettore CHIM/06 - Chimica Organica04 agricultural and veterinary sciencesCell Biologybiology.organism_classification040401 food sciencehumanities0104 chemical sciencesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreePrunus dulcisProanthocyanidinPhytochemicalLC-ESI/LTQOrbitrap/ MSTherapeutics. PharmacologyRubus ulmifoliusAntioxidants
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Xenopus Oocyte’s Conductance for Bioactive Compounds Screening and Characterization

2019

Background: Astaxanthin (ATX) is a lipophilic compound found in many marine organisms. Studies have shown that ATX has many strong biological properties, including antioxidant, antiviral, anticancer, cardiovascular, anti-inflammatory, neuro-protective and anti-diabetic activities. However, no research has elucidated the effect of ATX on ionic channels. ATX can be extracted from shrimp by-products. Our work aims to characterize ATX cell targets to lend value to marine by-products. Methods: We used the Xenopus oocytes cell model to characterize the pharmacological target of ATX among endogenous Xenopus oocytes&rsquo

AntioxidantSodiummedicine.medical_treatmentXenopuschemistry.chemical_elementEndogeny+Sodium ChannelsCatalysisArticleAmilorideInorganic Chemistrylcsh:ChemistryXenopus laevischemistry.chemical_compoundXenopus oocyte INaAstaxanthinDrug DiscoverymedicineAnimalsPhysical and Theoretical ChemistryMolecular BiologyIC50lcsh:QH301-705.5SpectroscopyXenopus oocyte INa+Biological Productsbioactive compoundsbiologySodium channelOrganic Chemistry<i>Xenopus</i> oocyte INa<sup>+</sup>marine natural productsGeneral Medicinebiology.organism_classificationElectrophysiological PhenomenaComputer Science ApplicationsShrimpastaxanthinchemistryBiochemistrylcsh:Biology (General)lcsh:QD1-999OocytesInternational Journal of Molecular Sciences
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Accelerated Solvent Extraction and Pulsed Electric Fields for Valorization of Rainbow Trout (Oncorhynchus mykiss) and Sole (Dover sole) By-Products: …

2021

Fishery by-products are rich in biologically active substances and the use of green and efficient extraction methods to recover these high-added-value compounds is of particular importance. In this study, head, skin and viscera of rainbow trout and sole were used as the target matrices and accelerated solvent extraction (ASE) (45–55 °C, 15 min, pH 5.2–6.8, 103.4 bars) and pulsed electric fields (PEF) (1–3 kV/cm, 123–300 kJ/kg, 15–24 h) were applied as extraction technologies. The results showed that ASE and PEF significantly increased the protein extract efficiency of the fish by-products (p < 0.05) by up to 80%. SDS-PAGE results showed that ASE and PEF treatments changed the molecular size…

AntioxidantantioxidantTime FactorsOxygen radical absorbance capacityFood Handlingmedicine.medical_treatmentPharmaceutical ScienceChemical Fractionation01 natural sciencesAntioxidantschemistry.chemical_compoundDover soleElectricityDrug DiscoveryFood sciencelcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Polyacrylamide gel electrophoresisABTSTemperature04 agricultural and veterinary sciencesHydrogen-Ion Concentration040401 food science6. Clean waterOncorhynchus mykissFlatfishesMolar mass distributionElectrophoresis Polyacrylamide GelAntioxidantFish Proteinsanimal structuresFish by-productsArticleASE0404 agricultural biotechnologyfoodmedicinePressureAnimals14. Life underwaterWaste Productsfish by-productsOxygen Radical Absorbance CapacityProtein010401 analytical chemistryExtraction (chemistry)PEFfood.food0104 chemical sciencesMolecular Weightlcsh:Biology (General)chemistrySeafoodSolventsRainbow troutproteinSDS-PAGE
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Plant Sterols and Antioxidant Parameters in Enriched Beverages: Storage Stability

2012

Plant sterols (PS) stability, antioxidant parameters, and color were studied during 6 months of storage at 4, 24, and 37 °C in three PS-enriched functional beverages. Beverages were skimmed milk with fruit juice and PS (MFJPS), fruit juice and PS (FJPS), and skimmed milk with PS (MPS). No loss in total PS content occurred during storage observing the same values at any given storage time point. Total carotenoids decreased 36% with storage at two months and then remained stable. Total polyphenols showed fluctuations throughout the storage, remaining stable at 6 months and reaching initial values. The antioxidant capacity (TEAC method) increased 18% at 6 months, and there was an increase in c…

Antioxidantfood.ingredientmedicine.medical_treatmentAntioxidantsBeveragessymbols.namesakefoodSkimmed milkmedicineFood scienceCarotenoidchemistry.chemical_classificationPhytosterolsGeneral ChemistryMaillard reactionAntioxidant capacityFood StoragechemistrySpainPolyphenolFruitFood FortifiedsymbolsFruit juiceDairy ProductsGeneral Agricultural and Biological SciencesPlant sterolsJournal of Agricultural and Food Chemistry
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Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a…

2021

Aqueous extracts from blackcurrant press cake (BC), Norway spruce bark (NS), Scots pine bark (SP), and sea buckthorn leaves (SB) were obtained using maceration and pressurized hot water and tested for their bioactivities. Maceration provided the extraction of higher dry matter contents, including total phenolics (TPC), anthocyanins, and condensed tannins, which also impacted higher antioxidant activity. NS and SB extracts presented the highest mean values of TPC and antioxidant activity. Individually, NS extract presented high contents of proanthocyanidins, resveratrol, and some phenolic acids. In contrast, SB contained a high concentration of ellagitannins, ellagic acid, and quercetin, exp…

Antioxidantmedicine.medical_treatmentAnti-Inflammatory AgentsToxicologyAntioxidantschemistry.chemical_compoundRibesAnti-Infective AgentsCandida albicansHippophaeFood sciencenatural resources0303 health sciencesbiologyChemistrybioaktiiviset yhdisteetPinus sylvestris04 agricultural and veterinary sciencesGeneral Medicine040401 food scienceEnterovirus B HumanProanthocyanidinvisual_artPlant Barkvisual_art.visual_art_mediumkiertotalousBarkQuercetinEllagic acidfree radicalsMicrobial Sensitivity Testsvapaat radikaalit03 medical and health sciences0404 agricultural biotechnologyindustrial by-productsCell Line TumormedicineMaceration (wine)HumansPress cakebiomassa (teollisuus)Picea030304 developmental biologyantioksidantitantimikrobiset yhdisteetbioactive compoundsBacteriaPlant Extractscircular economyScots pineGreen Chemistry Technologybiology.organism_classificationluonnonaineetextraction technologiesPlant Leavesuuttosivutuotteetmyrkylliset aineetFood Science
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Critical review: Grand challenges in assessing the adverse effects of contaminants of emerging concern on aquatic food webs

2019

Much progress has been made in the past few decades in understanding the sources, transport, fate, and biological effects of contaminants of emerging concern (CECs) in aquatic ecosystems. Despite these advancements, significant obstacles still prevent comprehensive assessments of the environmental risks associated with the presence of CECs. Many of these obstacles center around the extrapolation of effects of single chemicals observed in the laboratory or effects found in individual organisms or species in the field to impacts of multiple stressors on aquatic food webs. In the present review, we identify 5 challenges that must be addressed to promote studies of CECs from singular exposure e…

Aquatic OrganismsFood ChainAquatic toxicologyHealth Toxicology and MutagenesisOtras Ciencias Biológicas010501 environmental sciences01 natural sciencesAquatic organismsAquatic toxicologyCiencias Biológicas//purl.org/becyt/ford/1 [https]03 medical and health sciencesAquatic speciesSpecies Specificityaquatic food webEnvironmental ChemistrypharmaceuticaleffectsEcological risk assessment//purl.org/becyt/ford/1.6 [https]Endocrine disruptorsEnvironmental planning030304 developmental biology0105 earth and related environmental sciencesGrand ChallengesTrophic level0303 health sciencesAquatic ecosystemEnvironmental ExposureFood webPersonal care productsAquatic environmentMixturescardiovascular systemPharmaceuticalsEnvironmental sciencecontaminantsCIENCIAS NATURALES Y EXACTASWater Pollutants Chemical
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Insight into the Mechanism of Action of Marine Cytotoxic Thiazinoquinones

2017

The electrochemical response of four natural cytotoxic thiazinoquinones isolated from the Aplidium species was studied using conventional solution-phase and solid-state techniques, based on the voltammetry of immobilized particles methodology. The interaction with O-2 and electrochemically generated reactive oxygen species (ROS) was electrochemically monitored. At the same time, a molecular modeling study including density functional theory (DFT) calculations was performed in order to analyze the conformational and electronic properties of the natural thiazinoquinones, as well as those of their reduced intermediates. The obtained electrochemical and computational results were analyzed and c…

Aquatic OrganismsMolecular modelStereochemistryBioactive natural products; Cytotoxic activity; DFT calculations; Electrochemistry; Reactive radical species; Thiazinoquinones; Animals; Electrochemistry; Quinones; Reactive Oxygen Species; Aquatic Organisms; Urochordata; Drug Discovery3003 Pharmaceutical ScienceThiazinoquinoneDFT calculationPharmaceutical Science02 engineering and technologyDFT calculationsElectrochemistry01 natural sciencesArticleAplidiumbioactive natural products; thiazinoquinones; electrochemistry; DFT calculations; reactive radical species; cytotoxic activityComputational chemistryDrug DiscoverymedicineAnimalsCytotoxic T cellUrochordataBioactive natural productlcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Voltammetrycytotoxic activitychemistry.chemical_classificationReactive oxygen speciesbiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceQuinonesReactive radical specie021001 nanoscience & nanotechnologybiology.organism_classification0104 chemical scienceslcsh:Biology (General)electrochemistryMechanism of actionchemistryreactive radical speciesbioactive natural productsthiazinoquinonesDensity functional theorymedicine.symptomReactive Oxygen Species0210 nano-technologyMarine Drugs
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