Search results for "Products"
showing 10 items of 980 documents
Advanced strategy to exploit wine-making waste by manufacturing antioxidant and prebiotic fibre-enriched vesicles for intestinal health.
2020
Grape extract-loaded fibre-enriched vesicles, nutriosomes, were prepared by combining antioxidant extracts obtained from grape pomaces and a prebiotic, soluble fibre (Nutriose®FM06). The nutriosomes were small in size (from ∼140 to 260 nm), homogeneous (polydispersity index < 0.2) and highly negative (∼ −79 mV). The vesicles were highly stable during 12 months of storage at 25 °C. When diluted with warmed (37 °C) acidic medium (pH 1.2) of high ionic strength, the vesicles only displayed an increase of the mean diameter and a low release of the extract, which were dependent on Nutriose concentration. The formulations were highly biocompatible and able to protect intestinal cells (Caco-2) fro…
Metal ions modify DNA-protecting and mutagen-scavenging capacities of the AV-153 1,4-dihydropyridine.
2019
Abstract 1,4-Dihydropyridines (1,4-DHP) possess important biochemical and pharmacological properties, including antioxidant and antimutagenic activities. AV-153-Na, an antimutagenic and DNA-repair enhancing compound was shown to interact with DNA by intercalation. Here we studied DNA binding of several AV-153 salts to evaluate the impact of AV-153 modifications on its DNA binding capacity, the ability to scavenge the peroxynitrite, to protect HeLa and B-cells cells against DNA damage. Affinity of the AV-153 salts to DNA measured by a fluorescence assay was dependent on the metal ion forming a salt in position 4 of the 1,4-DHP, and it decreased as follows: Mg > Na > Ca > Li > Rb > K. AV-153-…
A reduction theorem for a conjecture on products of two π -decomposable groups
2013
[EN] For a set of primes pi, a group X is said to be pi-decomposable if X = X-pi x X-pi' is the direct product of a pi-subgroup X-pi and a pi'-subgroup X-pi', where pi' is the complementary of pi in the set of all prime numbers. The main result of this paper is a reduction theorem for the following conjecture: "Let pi be a set of odd primes. If the finite group G = AB is a product of two pi-decomposable subgroups A = A(pi) x A(pi') and B = B-pi x B-pi', then A(pi)B(pi) = B(pi)A(pi) and this is a Hall pi-subgroup of G." We establish that a minimal counterexample to this conjecture is an almost simple group. The conjecture is then achieved in a forthcoming paper. (C) 2013 Elsevier Inc. All ri…
Finitary Representations and Images of Transitive Finitary Permutation Groups
1999
Abstract We characterize the point stabilizers and kernels of finitary permutation representations of infinite transitive groups of finitary permutations. Moreover, the number of such representations is determined.
Sample Preparation to Determine Pharmaceutical and Personal Care Products in an All-Water Matrix: Solid Phase Extraction
2020
© 2020 by the authors. Pharmaceuticals and personal care products (PPCPs) are abundantly used by people, and some of them are excreted unaltered or as metabolites through urine, with the sewage being the most important source to their release to the environment. These compounds are in almost all types of water (wastewater, surface water, groundwater, etc.) at concentrations ranging from ng/L to µg/L. The isolation and concentration of the PPCPs from water achieves the appropriate sensitivity. This step is mostly based on solid-phase extraction (SPE) but also includes other approaches (dispersive liquid-liquid microextraction (DLLME), buckypaper, SPE using multicartridges, etc.). In this rev…
Safety of the current drug treatments for vitiligo
2020
Introduction: Vitiligo is an acquired depigmenting skin disorder adversely affecting the patient's quality of life. Despite the presence of several treatment modalities, ranging from medical to physical to surgical options, none is curative. Each modality has its own drawbacks and side effects. Thus, the treatment modality needs to be tailored for each individual patient taking into consideration the disease characteristics and also its efficacy and safety to obtain a favorable risk-benefit ratio.Areas covered: This review highlights the different treatment modalities utilized in vitiligo up until 4 November 2019 along with their adverse effects and contraindications, if any.Expert opinion:…
Multi-residue determination of 47 organic compounds in water, soil, sediment and fish—Turia River as case study
2017
A sensitive and reliable method based on solid-liquid extraction (SLE) using McIlvaine-Na2EDTA buffer (pH = 4.5)-methanol and solid-phase extraction (SPE) clean up prior to ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS) was applied to determine 47 organic contaminants in fish, soil and sediments. The SPE procedure to clean-up the extracts was also used as extraction method to determine these compounds in water. Recoveries ranged from 38 to 104% for all matrices with RSDs 50% for 36 compounds in front of 9, matrix effect < 20% for 31 compounds against 21, and LOQs <25 ng g−1 for 38 compounds against 22) indicates that the proposed method is mor…
Impressing my friends: The role of social value in green purchasing attitude for youthful consumers
2021
Abstract Prior studies predominantly use cross-sectional designs to determine effects of pro-environmental beliefs on green purchasing attitudes, thereby limiting the possibility for causal inferences and examining mediation effects. We overcome these gaps by adopting a two-wave longitudinal design to test a moderated-mediation model that draws on consumer choice theory, positing that the effect of implicit pro-environmental beliefs on green purchasing attitudes is mediated by perceived social value from buying green, while the relationship between pro-environmental beliefs and perceived social value is moderated by perceived inconvenience of buying green. Findings from a sample of Polish y…
Discovery of varlaxins, new aeruginosin-type inhibitors of human trypsins
2022
Low-molecular weight natural products display vast structural diversity and have played a key role in the development of novel therapeutics. Here we report the discovery of novel members of the aeruginosin family of natural products, which we named varlaxins. The chemical structures of varlaxins 1046A and 1022A were determined using a combination of mass spectrometry, analysis of one- and two-dimensional NMR spectra, and HPLC analysis of Marfey's derivatives. These analyses revealed that varlaxins 1046A and 1022A are composed of the following moieties: 2-O-methylglyceric acid 3-O-sulfate, isoleucine, 2-carboxy-6-hydroxyoctahydroindole (Choi), and a terminal arginine derivative. Varlaxins 10…
Desarrollo de productos avanzados para la misión SEOSAT/Ingenio
2016
SEOSAT/Ingenio es la futura misión española de observación de la Tierra en el óptico en alta resolución espacial. Mientras que los productos de imagen a Nivel 1, radiancias geo-referenciadas a nivel de sensor, se encuentran en una fase avanzada de desarrollo existiendo para ello un contrato industrial, los productos de Nivel 2 deben ser desarrollados por los propios usuarios. Este hecho limita el uso de las imágenes a la comunidad científica, restringiendo sus posibles aplicaciones fuera de ésta. Así pues, bajo el marco de un proyecto coordinado y motivados por ofrecer productos de Ingenio/SEOSAT de Nivel 2 a disposición de cualquier usuario, se origina y desarrolla este trabajo. En este ar…