Search results for "Programming"
showing 10 items of 3090 documents
Improved column-based radiochemical processing of the generator produced 68Ga.
2011
An improved chemical strategy for processing of the generator produced (68)Ga was developed based on processing of the original (68)Ge/(68)Ga generator eluate on a micro-column. Direct pre-concentration and purification of the eluted (68)Ga is performed on a cation-exchange resin in hydrochloric acid/acetone media. A supplementary step based on a second micro-column filled with a second resin allows direct re-adsorption of (68)Ga eluted from the cation exchanger. (68)Ga is finally striped from the second resin with a small volume of pure water. For this purpose a strong anion exchanger and a novel extraction chromatographic resin based on tetraalkyldiglycolamides are characterized. The stra…
Maturation of a Key Resource – The Germanium-68/Gallium-68 Generator: Development and New Insights
2011
(68)Ge/(68)Ga radionuclide generators have been investigated for almost fifty years, since the cyclotron-independent availability of positron emitting (68)Ga via the (68)Ge/(68)Ga system had always attracted researches working in basic nuclear chemistry as well as radiopharmaceutical chemistry. However, it took decades and generations of research (and researchers) to finally reach a level of (68)Ge/(68)Ga radionuclide generator designs adequate to the modern requirements of radiometal labelling chemistry. Nevertheless, most of the existing commercial generator systems address aspects of (68)Ge breakthrough and safe synthesis of (68)Ga radiopharmaceuticals by adopting eluate post-processing …
Regulation of T-Cell Immune Responses by Pro-Resolving Lipid Mediators
2021
Both the initiation and the resolution of inflammatory responses are governed by the sequential activation, migration, and control/suppression of immune cells at the site of injury. Bioactive lipids play a major role in the fine-tuning of this dynamic process in a timely manner. During inflammation and its resolution, polymorphonuclear cells (PMNs) and macrophages switch from producing pro-inflammatory prostaglandins and leukotrienes to specialized pro-resolving lipid mediators (SPMs), namely, lipoxins, resolvins, protectins, and maresins, which are operative at the local level to limit further inflammation and tissue injury and restore homeostasis. Accumulating evidences expand now the rol…
Indeterminacy Reduction in Agent Communication Using a Semantic Language
2015
In recent years, the importance of vagueness and uncertainty in the messages exchanged between agents has been highlighted, mainly due to the ubiquitous nature of the (artificial or human) agents’ communication. The imprecision in the communication becomes more significant when the autonomy of the agents increases or the number of exchanged messages for a communicative goal is limited. In this paper we conjugate ideas drawn from situation semantics theory, human communication, and the multi-agent systems (MAS) field to reduce the impact of vagueness and uncertainty present in the communication. The main advances are achieved with the help of context information, collaboration and reinforcem…
Change-Dominant Characteristic of the 21st Century and Essential Factor for Organizational Success
2013
Abstract This paper aims to bring to the forefront change, because it is known that this dominant characteristic of the third millennium has a major impact on the business world, on organizations and on management. In this context, the organizations of the future are changing organizations, they are organizations whose managers have understood the necessity of implementing change and have accepted without reserve the reality that progress requires change.
Revista iberoamericana de educación
2012
Título, resumen y palabras clave en español, portugués e inglés Monográfico con el título: "Didáctica de la Lengua y la Literatura" Resumen tomado de la publicación Se propone el examen de las implicaciones del concepto de género discursivo, tomado de M. Bajtín, para la enseñanza de la composición escrita dentro del marco metodológico de las secuencias didácticas. Además de situar la enseñanza en un marco comunicativo, integra los aprendizajes específicos de habilidades lingüístico-comunicativas dentro de una tarea global que les da sentido. Se destaca de un modo especial la importancia de esta integración en cuanto a los conocimientos explícitos sobre la lengua y sus condiciones de uso. Se…
HOWERD: A Hidden Markov Model for Automatic OWL-ERD Alignment
2016
The HOWERD model for estimating the most likely alignment between an OWL ontology and an Entity Relation Diagram (ERD) is presented. Automatic alignment between relational schema and ontology represents a big challenge in Semantic Web research due to the different expressiveness of these representations. A relational schema is less expressive than the ontology; this is a non trivial problem when accessing data via an ontology and for ontology storing by means of a relational schema. Existent alignment methodologies fail in loosing some contents of the involved representations because the ontology captures more semantic information, and several elements are left unaligned. HOWERD relies on a…
Spatialization of the Semantic Web
2012
syntax for Horn-like rules. The SWRL as the form, antecedentconsequent, where both antecedent and consequent are conjunctions of atoms written a1^ ... ^ an. Atoms in rules can be of the form C(x), P(x,y), Q(x,z), sameAs(x,y), differentFrom(x,y), or builtIn(pred, z1, ..., zn), where C is an OWL description, P is an OWL individual-valued property, Q is an OWL data-valued property, pred is a datatype predicate URIref, x and y are either individual-valued variables or OWL individuals, and z, z1, ... zn are either data-valued variables or OWL data literals. An OWL data literal is either a typed literal or a plain literal. Variables are indicated by using the standard convention of prefixing the…
Working with Multiple Ontologies on the Semantic Web.
2016
The standardization of the second generation Web Ontology Language, OWL, leaves a crucial issue for Web-based ontologies unsatisfactorily resolved: how to represent and reason with multiple distinct, but linked, ontologies. OWL provides the owl:imports construct which, roughly, allows Web ontologies to include other Web ontologies, but only by merging all the linked ontologies into a single logical "space". Recent work on multidimensional logics, fusions and other combinations of modal logics, distributed and contextual logics, and the like have tried to find formalisms wherein knowledge bases (and their logic) are kept more distinct but yet affect each other. These formalisms have various …
Specific protocol (SENSLOG) over TCP/IP for sensors applications
2005
The objective is to obtain an embedded system using a microcontroller that will communicate with other devices over a specific protocol (SENSLOG) over TCP/IP for sensors applications. The protocol has been designed for this application, but the commands are generic. They can be used for any type of sensing. We must take into account that this program will run in a microcontroller and it will communicate with another program running in a PC. The protocol is based on commands, like SMTP. From the PC we will send commands to the microcontroller to do specific tasks, and if it is necessary, the microcontroller will answer to the PC. Some of the functions designed for this protocol are: to contr…