Search results for "Proof of Concept"
showing 10 items of 41 documents
Consistency Analysis of Genome-Scale Models of Bacterial Metabolism: A Metamodel Approach.
2015
Genome-scale metabolic models usually contain inconsistencies that manifest as blocked reactions and gap metabolites. With the purpose to detect recurrent inconsistencies in metabolic models, a large-scale analysis was performed using a previously published dataset of 130 genome-scale models. The results showed that a large number of reactions (~22%) are blocked in all the models where they are present. To unravel the nature of such inconsistencies a metamodel was construed by joining the 130 models in a single network. This metamodel was manually curated using the unconnected modules approach, and then, it was used as a reference network to perform a gap-filling on each individual genome-s…
RFID passive gas sensor integrating carbon nanotubes
2011
Carbon nanotube (CNT) composites are sensitive to the presence of gases due to their high surface-to-volume ratio and hollow structure that are well suited for gas molecule absorption and storage. Such sensing capability is here integrated with UHF RF identification (RFID) technology to achieve passive and low-cost sensors, remotely readable. CNT film (buckypaper) is used as a localized variable resistive load integrated into a tag antenna, which becomes able to transduce the presence of hazardous gas in the environment, ammonia in this case, into a change of its electromagnetic features. The dynamic range and the hysteresis of the radio sensor are investigated by simulations, equivalent ci…
Infrared based saliva screening test for COVID‐19
2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented need for diagnostic testing that is critical in controlling the spread of COVID-19. We propose a portable infrared spectrometer with purpose-built transflection accessory for rapid point-of-care detection of COVID-19 markers in saliva. Initially, purified virion particles were characterized with Raman spectroscopy, synchrotron infrared (IR) and AFM-IR. A data set comprising 171 transflection infrared spectra from 29 subjects testing positive for SARS-CoV-2 by RT-qPCR and 28 testing negative, was modeled using Monte Carlo Double Cross Validation with 50 randomized test and model sets. The testing se…
A Tool-Based Approach for Essentializing Software Engineering Practices
2019
Software Engineers work using highly diverse methods and practices, and general theories in software engineering are lacking. A recent attempt at creating a common ground in the area of software engineering methodologies has been the Essence Theory of Software Engineering. Essence is a method-agnostic progress management framework and a meta-method for Software Engineering (SE). However, tooling for Essence is still lacking. Without dedicated tools and other instruments, a meta-method such as Essence is cumbersome to utilize by practitioners and students. Indeed, Essence currently suffers from a lack of widespread practitioner adoption. In this paper, we thus present an Open Source tool for…
Self-powered IoT Device based on Energy Harvesting for Remote Applications
2018
In this paper, we present the design and prototype implementation of self-powered Internet of Things (IoT) device based on energy harvesting from a small solar panel of size 63mm x 63mm and 0.36W for remote applications. These IoT devices can be deployed in remote places within the range of a gateway. A complete proof of concept IoT device based on ambient energy harvesting is designed, prototyped and tested with super capacitors and Lithium cells in star topology. Based on the measurements, the IoT device can potentially last for one year with 55 seconds transmission interval with the fully charged 120mAh coin cell battery. On the other hand, a fully charged single 5F supercapacitor lasts …
Code Interoperability and Standard Data Formats in Quantum Chemistry and Quantum Dynamics: The Q5/Q5cost Data Model
2014
Code interoperability and the search for domain-specific standard data formats represent critical issues in many areas of computational science. The advent of novel computing infrastructures such as computational grids and clouds make these issues even more urgent. The design and implementation of a common data format for quantum chemistry (QC) and quantum dynamics (QD) computer programs is discussed with reference to the research performed in the course of two Collaboration in Science and Technology Actions. The specific data models adopted, Q5Cost and D5Cost, are shown to work for a number of interoperating codes, regardless of the type and amount of information (small or large datasets) …
Pulse doubling and wavelength conversion through triangular nonlinear pulse reshaping
2011
International audience; We present a proof of principle experiment demonstrating the benefits of using a triangular temporal profile in the context of copying and wavelength conversion of telecommunication signals. Generated by passive nonlinear reshaping in a set of two carefully chosen fibres, the triangular shape enables efficient temporal and spectral doubling of the signals through self-phase modulation.
Modular Assembly of Multimodal Imaging Agents through an Inverse Electron Demand Diels–Alder Reaction
2019
International audience; The combination of two imaging probes on a same biomolecule gives access to targeted bimodal imaging agents that can provide more accurate diagnosis, complementary information, or that may be used in different applications, such as PET imaging and fluorescence imagingassisted surgery. In this study, we demonstrate that dichlorotetrazine, a small, commercially available compound, can be used as a modular platform to easily assemble various imaging probes. Doubly-labeled tetrazines can then be conjugated to a protein through a biorthogonal IEDDA reaction. A series of difunctionalized tetrazine compounds containing various chelating agents and fluorescent dyes was synth…
Scalable Electro-Optic Control of Localized Bistable Switching in Broad-Area VCSELs Using Reconfigurable Funnel Waveguides
2017
We demonstrate a steplike optical modulation based on the activation and deactivation of a bistable localized structure using a photoinduced and reconfigurable miniaturized 30 × 30 μm electroactivated funnel waveguide. Control of a single 10-μm-diameter spot in a 200-μm-diameter vertical-cavity surfaceemitting laser at 980 nm is achieved modulating the phase of an exciting beam in the specific position of the spot in the cavity. This localized on-off response can be scaled into arrays and offer a possible route to fast integrated optical logical functions and memory at low intensities at near-infrared wavelengths.
Single snapshot RGB multispectral imaging at fixed wavelengths: proof of concept
2014
A concept of single snapshot multispectral imaging by standard RGB image sensors under spectrally-specific illumination comprising a fixed number of narrow spectral lines is discussed and experimentally validated. The limiting conditions, RGB band spectral crosstalk corrections and potential applications for parametric mapping of skin are regarded, along with the preliminary results of the proof-of-concept measurements.