Search results for "Protection"
showing 10 items of 1623 documents
Assessing the impact of agri-environmental schemes on the eco-efficiency of rain-fed agriculture
2012
This paper analyses the impact of the Agri-environmental Extensification Scheme for the Protection of Flora and Fauna (F&F Scheme) on the eco-efficiency of a sample of dryland farms in the Spanish region of Castile and Leon. Using Data Envelopment Analysis (DEA) and the so-called program decomposition approach to efficiency measurement, we explore whether or not the production technology of the farms included in the F&F Scheme is more eco-efficient than the technology used by farms that are not included in the Scheme. The re-sults obtained confirm the foregoing hypothesis, providing evidence that environmental pres-sures could be reduced if all farms adopted the F&F Scheme technology. Furth…
PASSENGER NAME RECORD (PNR)
2018
Lo scritto prende in esame la questione relativa al trattamento e al trasferimento dei dati personali dei passeggeri (PNR) nel trasporto aereo, con lo scopo di combattere il terrorismo internazionale e la criminalità transnazionale. La questione è stata molto dibattuta a livello europeo, a partire dal primo accordo tra USA-Ue nel 2004, poi abrogato dalla Corte di giustizia Ue, sino ai tempi più recenti, con l’approvazione della direttiva 681/2016 e il parere 1/15 del 2017 della Corte di giustizia sulla compatibilità tra l’accordo Ue-Canada e il vigente quadro normativo dell’Ue, successivo all’entrata in vigore del trattato di Lisbona e della Carta dei diritti fondamentali dell’Unione europe…
Annoyance due to residential road traffic and aircraft noise: Empirical evidence from two European cities
2021
Based on a study in two European cities, Mainz in Germany and Zurich in Switzerland, the article investigates both acoustical and non-acoustical factors affecting indoor annoyance due to residential road traffic and aircraft noise. We specifically focus on three factors: (1) the role of windows as a feature of the building where people live; (2) the role of individual environmental concern as a general attitude; and (3) the role of household income as an indicator of socioeconomic resources. Empirical results show that closed windows in general and closed high-quality windows in particular are an important barrier against outdoor road traffic and aircraft noise, as well as a helpful subject…
Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates
2021
LRP1-targeted St-Cl–polyglutamate conjugates as multivalent neuroprotective/neurotrophic therapeutics for Alzheimer’s disease.
AMBIENTE E TUTELA INDIVIDUALE INTERGENERAZIONALE
2020
Il saggio propone una riflessione sulla possibilità di una tutela ambientale individuale ed intergenerazionle, muovendo da una ricostruzione del concetto di ambiente nella prospettiva esistenzialista, segnata dal tessuto valoriale costituzionale interno ed europeo e dall’affermazione del principio dello sviluppo sostenibile. La valorizzazione dell’ambiente nella teoria dei beni trova nel dibattito sui beni comuni nuovi orizzonti di senso, coniugando la prospettiva esistenzialista del danno ambientale con quella propria della teorica dei beni comuni. All’esito di tale percorso ricostruttivo, avvalorato dalle recenti pronunce della Corte europea, l’autore giunge a fondare una legittimazione i…
Gli anfiteatri di Campania e Sicilia, 'pietre miliari' nella storia della tutela in età borbonica. Amphitheatres of Campania and Sicily, ‘milestones’…
2017
Il breve studio vuole essere occasione per richiamare le vicende legate alla progressiva salvaguardia del patrimonio culturale dell'Italia meridionale, al tempo dei Borbone. Sottolineando l'opportunità di riprendere, in un disegno complessivo, il quadro relativo ai due regni - di Napoli e di Sicilia - per le interrelazioni ancora da studiare e porre in evidenza, il saggio si sofferma in modo specifico sulle ricadute che le azioni condotte sugli anfiteatri campani avevano su quelli siciliani. Si è ripercorso l'iter di tutela e restauro degli anfiteatri e dei teatri di Catania e Siracusa, alla luce di una chiave critica e interpretativa formulata nel secondo Novecento, relativa al progressivo…
Emerging contributions of formyl peptide receptors to neurodegenerative diseases.
2021
Abstract Inflammation is a central element of many neurodegenerative diseases. Formyl peptide receptors (FPRs) can trigger several receptor-dependent signal transduction pathways that play a key role in neuroinflammation and neurodegeneration. They are chemotactic receptors that help to regulate pro- and anti-inflammatory responses in most mammals. FPRs are primarily expressed in the immune and nervous systems where they interact with a complex pattern of pathogen-derived and host-endogenous molecules. Mounting evidence points towards a contribution of FPRs – via neuropathological ligands such as Amyloid beta, and neuroprotective ligands such as Humanin, Lipoxin A4, and Annexin A1 – to mult…
Oxidative stress in Alzheimer’s Disease: Implications for Prevention and Therapy
2006
Oxidative stress is a marker of neurodegeneration and has been recently shown to be also involved in the early stages of the pathogenesis of various neurodegenerative disorders. In general, all biomolecules of the cell can be oxidized and thereby damaged. Consequently, the concept of neuroprotection by antioxidants has been developed. In many cases the direct scavanging of free radicals have been used as a strategy to prevent oxidative stress damage and a variety of physiological and synthetic antioxidant molecules have been identified and synthesized including the female sex homone estrogen. In Alzheimer’s Disease amyloid-β protein on its way to brain deposition can also induce oxidative c…
Application of C1-Esterase Inhibitor During Reperfusion of Ischemic Myocardium
2001
Background—Complement activation during reperfusion of ischemic myocardium augments myocardial injury, and complement inhibition with C1-esterase inhibitor (C1-INH) at the time of reperfusion exerts marked cardioprotective effects in experimental studies. Application of C1-INH in newborns, however, was recently reported to have dangerous and even lethal side effects. This study addresses the essential role of dosage in studies using C1-INH.Methods and Results—Cardioprotection by C1-INH was examined in a pig model with 60 minutes of coronary occlusion followed by 120 minutes of reperfusion. C1-INH was administered intravenously 5 to 10 minutes before coronary reperfusion without heparin at a…
Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells
2019
Abstract Background Cancer chemotherapy-induced cognitive impairments are apparently associated with harmful effects on physiological functions of brain cells. Adaptogens, are known to exhibit neuroprotective effects and to increase cognitive functions in clinical studies. In our previous study (Seo et al., 2018), we demonstrated that selected adaptogenic extracts significantly attenuate cytostatic-induced regulation of more than 100 genes involved in the activation of neuronal death and inhibiting neurogenesis. Neuroprotective and cytoprotective activities of adaptogens rise the question about their possible impact on cytostatic effects of a chemotherapeutic combination of 5-fluorouracil, …