Search results for "QT"
showing 10 items of 113 documents
Plasma Hyperosmolality Prolongs QTc Interval and Increases Risk for Atrial Fibrillation in Traumatic Brain Injury Patients
2020
Introduction: Hyperosmotic therapy with mannitol is frequently used for treatment cerebral edema, and 320 mOsm/kg H2O has been recommended as a high limit for therapeutic plasma osmolality. However, plasma hyperosmolality may impair cardiac function, increasing the risk of cardiac events. The aim of this study was to analyze the relation between changes in plasma osmolality and electrocardiographic variables and cardiac arrhythmia in patients treated for isolated traumatic brain injury (iTBI). Methods: Adult iTBI patients requiring mannitol infusion following cerebral edema, and with a Glasgow Coma Score below 8, were included. Plasma osmolality was measured with Osmometr 800 CLG. Spatial Q…
Overdose of Quetiapine—A Case Report with QT Prolongation
2021
Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge.
Solvent directs the dimensionality of Cu-dicyanoimidazoles
2022
In this paper, we report one-pot reactions of the same reactants 4,5-dicyanoimidazole and CuI in different solvents. In pure MeCN, the reaction resulted in previously reported MOF structure [Cu(4,5-dicyanoimidazole)]n.(MeCN)0.5n (1). On the other hand, when MeCN/MeOH solvent mixture was used, a new coordination polymer [Cu(4,5-dicyanoimidazole)(MeCN)(CuI)]n (2) was formed. The crystallization yielded very different structures as determined by X-ray crystallography. In 1, the solvent molecule acetonitrile occupies the MOF pores via weak interactions, but in 2 it is coordinated to the metal center. Computational DFT calculations and topological charge density analysis were utilized to explore…
Panorāmas attēlu marķēšanas rīks
2021
Kvalifikācijas darbā “Panorāmas attēlu marķēšanas rīks” izstrādāta programmatūra, kas nodrošina lietotājam iespēju apskatīt un marķēt panorāmas attēlus, izmantojot informāciju par telpu, kurā ir uzņemta panorāma. Rīks ir paredzēts, lai iegūtu papildu informāciju par objektiem tajā. Marķēšanas rīks izstrādāts C++ valodā, izmantojot Qt5 ietvaru. Darbs sastāv no sekojošām nodaļām: programmatūras prasību specifikācija, programmatūras projektējuma apraksts, projekta organizācija, kvalitātes nodrošināšana, konfigurāciju pārvaldība, testēšanas dokumentācija un darbietilpības novērtējums.
Augstas izšķirtspējas monitoru sienas vadības programmatūra
2015
Kvalifikācijas darba mērķis ir izstrādāt programmatūru augstas izšķirtspējas ekrānu un ekrānu kopumu vadībai. Sistēma tiks izstrādāta izmantojot starpplatformu lietojumprogrammu ietvaru “Qt” un tiks izmantota augstas izšķirtspējas ekrānu vadības atvieglošanai. Programmatūra funkcionēs gan caur lokālo, gan globālo tīklu.
Lietu internets kā pakalpojums
2018
Darba mērķis ir izstrādāt lietu interneta platformas arhitektūru, kura nodrošina daudzlietotāju atbalstu, ir viegli uzstādāma no galalietotāju skatupunkta, un kuru ir iespējams piedāvāt potenciāliem lietotājiem kā pakalpojumu, parūpējoties par tās uzstādīšanu un uzturēšanu. Darba gaitā ir veikts OpenHAB un Home Assistant lietu interneta platformu funkcionalitāšu apskats, salīdzinājums un to piemērotības izvērtējums daudzlietotāju arhitektūras izveidošanai. Darba rezultātā ir izveidots Home Assistant platformas arhitektūras risinājums, kurš ļauj veikt vienkāršu sākotnējo platformas uzstādīšanu, nodrošina daudzlietotāju atbalstu, izmantojot vairākas platformas instances vienā resursdatorā, un…
Mašīnmācīšanās pielietojums elektrības mirkļa cenas paredzēšanai
2016
Darba mērķis ir izpētīt mašīnmācīšanās pielietojumu konkrētas problēmas risināšanai. Izvēlētā pētāmā problēma ir elektrības cenas paredzēšana, izmantojot dažādus pieejamos faktorus par noteiktu laika periodu. Darbs tika izstrādāts sadarbojoties ar Viktoriju Bobinaiti, kura izstrādāja savu pētījumu „Modelling Electricity Price Expectations in a Day-Ahead Electricity Market”, no šī pētījuma tika iegūti atbilstošie dati. Darbā tika izveidota datorprogramma, kas pielieto specifisku mašīnmācīšanās veidu – neironu tīklus. Izveidota datorprogramma spēj parametrizēti izveidot neironu tīklus, ļaujot pielāgot gan apmācīšanas procesu, gan mainīt neironu tīkla struktūras parametrus, gan filtrēt pieejam…
Revisiting the charge density analysis of 2,5-dichloro-1,4-benzoquinone at 20 K
2017
A high-resolution X-ray diffraction measurement of 2,5-dichloro-1,4-benzoquinone (DCBQ) at 20 K was carried out. The experimental charge density was modeled using the Hansen–Coppens multipolar expansion and the topology of the electron density was analyzed in terms of the quantum theory of atoms in molecules (QTAIM). Two different multipole models, predominantly differentiated by the treatment of the chlorine atom, were obtained. The experimental results have been compared to theoretical results in the form of a multipolar refinement against theoretical structure factors and through direct topological analysis of the electron density obtained from the optimized periodic wavefunction. The si…
A Prototype of Wireless Sensor for Data Acquisition in Energy Management Systems
2018
A prototype of a wireless sensor for monitoring electrical loads in a smart building is designed and implemented. The sensor can acquire the main electrical parameters of the connected load and, optionally, other physical quantities (e.g., room temperature). Unlike other wireless sensors in literature, the proposed sensor is cheap and small, exploits the Wi-Fi network that is commonly available inside buildings, and uses a lightweight message-based communication paradigm. Besides the sensor node, two management nodes are also implemented to manage sensor reconfiguration and the persistence of data. The measured data are stored in an SQLite database and can be used for various purposes, e.g.…
New epicardial mapping electrode with warming/cooling function for experimental electrophysiology studies
2010
Cardiac electrical activity is influenced by temperature. In experimental models, the induction of hypothermia and/or hyperthermia has been used for the study of mechanisms of cardiac arrhythmia. A system that allows for localized, controlled induction, besides simultaneously recording electrical activity in the same induced area, needs to be developed ad hoc. This article describes the construction and application of a new system capable of locally modifying the epicardial temperature of isolated hearts and of carrying out cardiac mapping with sufficient spatial resolution. The system is based on a thermoelectric refrigerator and an array of 128 stainless steel unipolar electrodes in encap…