Search results for "R1"

Quantization on the Virasoro group

1990

The quantization of the Virasoro group is carried out by means of a previously established group approach to quantization. We explicitly work out the two-cocycles on the Virasoro group as a preliminary step. In our scheme the carrier space for all the Virasoro representations is made out of polarized functions on the group manifold. It is proved that this space does not contain null vector states, even forc≦1, although it is not irreducible. The full reduction is achieved in a striaghtforward way by just taking a well defined invariant subspace ℋ(c, h), the orbit of the enveloping algebra through the vacuum, which is irreducible for any value ofc andh. ℋ(c, h) is a proper subspace of the sp…

Graded polynomial identities and exponential growth

2009

Let $A$ be a finite dimensional algebra over a field of characteristic zero graded by a finite abelian group $G$. Here we study a growth function related to the graded polynomial identities satisfied by $A$ by computing the exponential rate of growth of the sequence of graded codimensions of $A$. We prove that the $G$-exponent of $A$ exists and is an integer related in an explicit way to the dimension of a suitable semisimple subalgebra of $A$.

On the nonarchimedean quadratic Lagrange spectra

2018

We study Diophantine approximation in completions of functions fields over finite fields, and in particular in fields of formal Laurent series over finite fields. We introduce a Lagrange spectrum for the approximation by orbits of quadratic irrationals under the modular group. We give nonarchimedean analogs of various well known results in the real case: the closedness and boundedness of the Lagrange spectrum, the existence of a Hall ray, as well as computations of various Hurwitz constants. We use geometric methods of group actions on Bruhat-Tits trees. peerReviewed

Renin-angiotensin system inhibitors effect before and during hospitalization in COVID-19 outcomes: Final analysis of the international HOPE COVID-19 …

2021

Background The use of Renin-Angiotensin system inhibitors (RASi) in patients with coronavirus disease 2019 (COVID-19) has been questioned because both share a target receptor site. Methods HOPE-COVID-19 (NCT04334291) is an international investigator-initiated registry. Patients are eligible when discharged after an in-hospital stay with COVID-19, dead or alive. Here, we analyze the impact of previous and continued in-hospital treatment with RASi in all-cause mortality and the development of in-stay complications. Results We included 6503 patients, over 18 years, from Spain and Italy with data on their RASi status. Of those, 36.8% were receiving any RASi before admission. RASi patients were …

Qualitative methods of structural analysis : layer-based methods are informationally trivial

2000

Some methods of qualitative structural analysis, as MFA, are based on the analysis of layers (flow matrices generated at each iteration when the equilibrium of an input-output model is computed). MFA mixes the analysis of the pure structure of production (the technical coefficients) and of the final demand. I have demonstrated that all column-coefficient matrices (or row-coefficient matrices) computed from each layer are the same in MFA: the information brought by one layer is identical to those of another layer. For a given structure of production, the only element of variability over layers is caused by the flows that final demand generates.If the new definition of layers proposed by the …

La nodalité : un concept fondamental de l’organisation de l’espace. Introduction au dossier

2005

Crispr gene editing in lipid disorders and atherosclerosis: Mechanisms and opportunities

2021

Elevated circulating concentrations of low-density lipoprotein cholesterol (LDL-C) have been conclusively demonstrated in epidemiological and intervention studies to be causally associated with the development of atherosclerotic cardiovascular disease. Enormous advances in LDL-C reduction have been achieved through the use of statins, and in recent years, through drugs targeting proprotein convertase subtilisin/kexin type 9 (PCSK9), a key regulator of the hepatic LDL-receptor. Existing approaches to PCSK9 targeting have used monoclonal antibodies or RNA interference. Although these approaches do not require daily dosing, as statins do, repeated subcutaneous injections are nevertheless neces…

Using mRNA and small RNA gene expression changes in peripheral blood for easy detection of Ra-223 incorporation

2019

Translocation of Zymomonas mobilis pyruvate decarboxylase to periplasmic compartment for production of acetaldehyde outside the cytosol

2019

Abstract Acetaldehyde, a valuable commodity chemical, is a volatile inhibitory byproduct of aerobic fermentation in Zymomonas mobilis and in several other microorganisms. Attempting to improve acetaldehyde production by minimizing its contact with the cell interior and facilitating its removal from the culture, we engineered a Z. mobilis strain with acetaldehyde synthesis reaction localized in periplasm. For that, the pyruvate decarboxylase (PDC) was transferred from the cell interior to the periplasmic compartment. This was achieved by the construction of a Z. mobilis Zm6 PDC‐deficient mutant, fusion of PDC with the periplasmic signal sequence of Z. mobilis gluconolactonase, and the follow…

(Table 1) Sea surface temperature reconstruction for eastern equatorial Pacific surface sediment samples

2012

Significant uncertainties persist in the reconstruction of past sea surface temperatures in the eastern equatorial Pacific, especially regarding the amplitude of the glacial cooling and the details of the post-glacial warming. Here we present the first regional calibration of alkenone unsaturation in surface sediments versus mean annual sea surface temperatures (maSST). Based on 81 new and 48 previously published data points, it is shown that open ocean samples conform to established global regressions of Uk'37 versus maSST and that there is no systematic bias from seasonality in the production or export of alkenones, or from surface ocean nutrient concentrations or salinity. The flattening…