Search results for "RACE"
showing 10 items of 4458 documents
Neo-clerodane diterpenoids from Conyza pyrrhopappa Sch.Bip. ex A.Rich
2019
Two hitherto unknown neo-clerodane-type diterpenoids along with twelve known compounds have been isolated from Conyza pyrrhopappa Sch.Bip. ex A.Rich, a medicinal plant traditionally used across tropical Africa to relieve fever. The structures of isolates have been elucidated by a combination of spectroscopic techniques. The crude extract and the isolated compounds were evaluated in the Hela-S3 cell line and in a panel of microorganisms (bacteria and fungi) at concentrations up to 50 µg/mL. The new compounds were inactive while the pentamethylated flavonoids showed low to significant activity against the cancer cell line used. However, none of the samples showed any activity against the test…
Composition of the essential oil ofPallenis spinosa (L.) Cass. (Asteraceae)
2003
The essential oil of Pallenis spinosa (L.) Cass. was obtained by hydrodistillation. In total 38 components were identified by GC and GC–MS. Oxygenated sesquiterpenoids amounted to 60.2% of the oil. The main components were germacra-1(10),5-dien-3,4-diol (18.4%), α-cadinol (14.1%), 3-acetoxygermacra-1(10),5-dien-4-ol (13.0%), T-cadinol (8.2%) and δ-cadinene (5.8%). The oil does not show antimicrobial activity. Copyright © 2003 John Wiley & Sons, Ltd.
Two new diterpenoids from kencur (Kaempferia galanga): Structure elucidation and chemosystematic significance
2021
Abstract Aromatic ginger or kencur (Kaempferia galanga L.) rhizomes are ground as a spice or pickled for consumption in south-east Asian cuisines; although widely used, until recently it has been less studied chemically than white and red ginger. Hydro-distillate extracts have identified several compounds that exhibit anticancer activity against select tumor cell lines in vitro, and most recently chemical analyses have focused on rhizome metabolites present in organic extracts. Here we report on two new diterpenoids including Δ8(14),15 polyhydroxlated isopimardienes, 1α-hydroperoxy-2α,6,7-trihydroxy-isopimara-6(7),8(14),15-triene (kaemgalangol E; 1) and 1α,7β-hydroxy-isopimara-8(14),15-dien…
Essential oil composition ofArtemisia parvi?ora aerial parts
2003
The chemical composition of the essential oil from aerial parts of A. parviflora was analysed by GC and GC–MS. Twenty-two compounds, accounting for 72.7% of the oil, were identified. The main components identified were β-caryophyllene (15.3%), germacrene D (14.7%), camphor (11.4%), artemisia ketone (7.8%), 1,8-cineole (5.8%), α-copaene (2.6%), artemisia alcohol (2.6%), terpinene-4-ol (2.3%), caryophyllene oxide (1.2%), α-pinene (1.1%), sabinyl acetate (1.1%) and α-humulene (1.1%). Copyright © 2003 John Wiley & Sons, Ltd.
Deux nouvelles traces de pas de Dinosaures du Trias supérieur de la bordure cévenole (la Grand-Combe, Sud-Est de la France)
2000
Resume Dans une formation sommitale a Argiles bariolees du Trias superieur francais, deux niveaux a traces depas inedites de Dinosaures ont ete decouverts. Elles se rapportent a l'association Otozoum/Grallator qui n'a jamais ete definie precisement en Europe. Sa position stratigraphique precise dans la serie triasique et la comparaison avec les associations ichnologiques des USA et d'Afrique du Sud, confirment l'âge Norien des niveaux a empreintes. Otozoum grandcombensis nov. ichnosp. correspond a des traces de pieds et de mains tetradactyles de meme taille, laissees par un animal bipede occasionnellement quadrupede. Il s'agissait probablement d'un, grand Prosauropode, d'une dizaine de m de…
Two new combinations inAdenostyles (Asteraceae, Senecioneae), a conspectus of the genus and key to its species and subspecies
2012
Abstract Dillenberger M. S. & Kadereit J. W.: Two new combinations in Adenostyles (Asteraceae, Senecioneae), a conspectus of the genus and key to its species and subspecies. — Willdenowia 42: 57-61. June 2012. — Online ISSN 1868-6397; © 2012 BGBM Berlin-Dahlem. Stable URL: http://dx.doi.org/10.3372/wi.42.42105 Based on a molecular phylogeny (using ITS, ETS and the rpl32-trnL, psbA-trnH and ndhF-rpl32 plastid spacer sequences) of all species and subspecies of the European genus Adenostyles currently recognised, and supported by the morphology of the leaf margin, we transfer two subspecies of A. alliariae to A. alpina and provide the new combinations A. alpina subsp. macrocephala and A. alpin…
Patterns and causes of incongruence between plastid and nuclear Senecioneae (Asteraceae) phylogenies
2010
One of the longstanding questions in phylogenetic systematics is how to address incongruence among phylogenies obtained from multiple markers and how to determine the causes. This study presents a detailed analysis of incongruent patterns between plastid and ITS/ETS phylogenies of Tribe Senecioneae (Asteraceae). This approach revealed widespread and strongly supported incongruence, which complicates conclusions about evolutionary relationships at all taxonomic levels. The patterns of incongruence that were resolved suggest that incomplete lineage sorting (ILS) and/or ancient hybridization are the most likely explanations. These phenomena are, however, extremely difficult to distinguish beca…
Cytochrome oxidase activity in the mitochondria of unfertilized and fertilized sea urchin eggs
1959
Abstract The cytochrome oxidase activity of isolated mitochondria of unfertilized and fertilized eggs of Paracentrotus lividus has been studied. It has been found that whereas in the mitochondria of unfertilized eggs saturation is reached at a cytochrome c concentration of 3.28 × 10−5 M, in those of fertilized eggs this occurs at a concentration of 5.74 × 10−5 M. It is shown that upon fertilization an increase of about 30 per cent of the activity of cytochrome oxidase takes place and no further changes appear to occur until blastula stage.
Pathogenesis of Atherosclerosis: The Alternative Hypothesis
1998
The concept that oxidation is the major single event underlying the transformation of LDL to a proinflammatory molecule dominates the world literature. An alternative hypothesis on the pathogenesis of atherosclerosis will be presented here. We have found that nonoxidative, enzymatic modification of LDL with ubiquitous enzymes also transforms the molecule to an atherogenic moiety. Enzymatically altered LDL (E-LDL) shares major properties in common with lipoproteins that have been isolated from atherosclerotic lesions. It activates complement and is recognized by a scavenger receptor on human macrophages, thus inducing foam cell formation. Uptake of E-LDL is accompanied by induction of MCP−1 …
Medicine among métis, phrónesis and téchne
2010
Cosi come si presenta la pillola del giorno dopo puo essere utilizzata in modo efficace fino a 72 ore dopo il rapporto sessuale non protetto. Tuttavia, in alcuni casi, questo periodo puo essere troppo breve. Per tale motivo, e stata commercializzata per la prima volta una pillola, l’acetato ulipristal (Ellaone), per la contraccezione d’emergenza post-coitale fino a 120 ore (5 giorni) dopo i rapporti sessuali non protetti o nel caso di insuccesso del contraccettivo. Un aspetto importante da considerare nella valutazione etica di un farmaco usato per la contraccezione d’emergenza e il suo meccanismo d’azione, in quanto tale valutazione sara molto diversa se il farmaco agisce inibendo o ritard…