Search results for "RAM"
showing 10 items of 35643 documents
3 ′-5 ′ crosstalk contributes to transcriptional bursting
2019
Abstract Background Transcription in mammalian cells is a complex stochastic process involving shuttling of polymerase between genes and phase-separated liquid condensates. It occurs in bursts, which results in vastly different numbers of an mRNA species in isogenic cell populations. Several factors contributing to transcriptional bursting have been identified, usually classified as intrinsic, in other words local to single genes, or extrinsic, relating to the macroscopic state of the cell. However, some possible contributors have not been explored yet. Here, we focus on processes at the 3 ′ and 5 ′ ends of a gene that enable reinitiation of transcription upon termination. Results Using Bay…
Immune Response Failure in Paucisymptomatic Long-Standing SARS-CoV-2 Spreaders
2021
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout the world. This disease has a spectrum of different clinical pictures with different outcomes. Herein, we report all the data from three paucisymptomatic patients during a hospital stay that might represent a paradigmatic example of the method by which SARS-CoV-2 is shed. We demonstrated the lack of an adequate qualitative and quantitative immune response by multiparametric flow cytometry analysis. Our data can provide a new perspective about the method by which SARS-CoV-2 is shed and the clinical weight of viral persistence. In all three cases, the …
FETAL GROWTH RESTRICTION: A GROWTH PATTERN WITH FETAL, NEONATAL AND LONG-TERM CONSEQUENCES
2019
Fetal growth restriction (FGR) or intrauterine growth restriction (IUGR) are the terms used for a fetus which has not attained its full growth potential for gestational age. FGR is a multifactorial syndrome responsible for increased fetal and neonatal morbidity and mortality as well as long term adverse outcomes involving auxological, metabolic, organic and functional domains. Clinicians distinguish early and late onset FGR, in relation to specific fetal anthropometric parameters related to the possible primary etiology and to different patterns of placental and maternal cardiovascular pathologies. Delivery of an early onset FGR or growth impaired newborn with congenital pathology should be…
THE CHALLENGE OF OPEN TIBIAL SHAFT FRACTURES: WHEN TOMANAGE WITH EXTERNAL FIXATION AND WHEN TO USEINTRAMEDULLARY NAILING?
2020
Treatment of open tibial shaft fractures is challenging. External fixation (EF) is comparatively safe in treating these open injuries with the main advantages of easy application, minimal additional disruption, and convenient subsequent soft tissue repair. Tibial intramedullary nailing (IM) is optimal for the treatment of open tibial fractures. This study aims to report the outcomes of our multi-center experience in the management of open tibial shaft fractures, evaluating the efficacy and safety of using either the external fixation (EF) or intramedullary nailing (IM).In this study, clinical-radiographic results were evaluated in 26 cases of open fractures treated with an external fixator …
Dannelse og samskaping av utdanning mellom akademia og sykehjem
2020
Cultivation and co-creation of education between academy and nursing home - a critical ethnography study Collaboration between academy and practice in education is emphasized. In this study, we explored and described boundary-crossing spaces, when co-creating an adjusted educational program for nursing students in a nursing home in Norway. Our aim was to explore how to learn person-centered dementia care through the participants in a learning community. A critical ethnographic approach and method with observations, field n otes, minutes of board, spontaneous meetings, and focus groups particularly with the students were used. Data were analyzed with six-step thematic analysis by Braun and…
Dieta del delfín de Risso (Grampus griseus) en el Mediterráneo occidental
2006
DIETA DEL DELFÍN DE RISSO (GRAMPUS GRISEUS) EN EL MEDITERRÁNEO OCCIDENTAL. – Se ha analizado el contenido gastrointestinal de quince ejemplares de Grampus griseus varados en el Mediterráneo occidental entre 40º25’N 00º32’W y 37º35’N 00º45’E durante el período 1987 a 2003. Los resultados indican una dieta teutófaga, basada principalmente en cefalópodos oceánicos destacando los octópodos pelágicos, especialmente Argonauta argo, como la presa más abundante (media = 41,28%; SD±34,32). Algunas especies pertenecientes a las familias mmastrephidae, Histioteuthidae y Onychoteuthidae son también componentes frecuentes de la misma. La distribución batimétrica de los cefalópodos indica que el área de …
Fomentar la resiliencia en familias con enfermedades crónicas pediátricas
2013
En este artículo se describen los diferentes enfoques que se pueden aplicar al estudio del concepto de resiliencia familiar en el contexto de las enfermedades crónicas pediátricas y sus implicaciones en la práctica clínica y educativa. Asimismo, se describen los principios generales que deben regir esta práctica y las actuaciones concretas de los profesionales de los sistemas sanitarios, educativos y sociales. La resiliencia familiar es imprescindible para mantener una buena calidad de vida del niño enfermo y de la familia en su conjunto.
Un programa de formación en lectura crítica en internet para jóvenes con discapacidad intelectual
2018
Delgado, P. et al. (2018): “Un programa de formación en lectura crítica en internet para jóvenes con discapacidad intelectual”. Revista Española de Discapacidad, 6 (II): 229-245.
A Group-Based 8-Week Functional Interval-Type Outdoor Training Program Improves Physical Performance in Recreationally Active Adults
2022
Even though physical activity is an important aspect of health, lack of time or motivation impede people from working out regularly. One type of training program that is both efficient and motivating is functional interval-type outdoor training. To evaluate this, our study had 81 participants complete a battery of physical performance tests (incremental treadmill test, core stability test and functional fitness test) before and after an 8-week outdoor interval-type training intervention. Training procedures included multimodal and high-intensity exercises performed in consistent, small groups. Results showed that the interval training program produced significant increases in the interventi…
Uddannelse som social kunstform?
2018
Malet med denne artikel er at undersoge nogle af de kunstneriske og paedagogiske dilemmaer, der kan opsta, nar man anvender praksisstyret aktionsforskning i udviklingen af egen undervisning i og gennem de kunstneriske fag ved et universitet. Ved at fokusere pa vanskelige situationer onsker artiklen at diskutere, hvad der sker, nar laerere og studerende sammen udforsker egne roller i de utydeligt afgraensede mellemrum og spaendinger mellem praksisformerne undervisning, forskning og kunst. I forste del av artiklen praesenteres didaktiske, kunstneriske og metodiske aspekter af forskningsprojektet Art as Education/Education as Art, hvor min kollega og jeg i efteraret 2016 sammen gennemforte en …