Search results for "RC86-88.9"

showing 10 items of 57 documents

Optimal doses of caspofungin during continuous venovenous hemodiafiltration in critically ill patients

2017

0301 basic medicineContinuous renal replacement therapymedicine.medical_specialtyLetterCritical Illness030106 microbiologyHemodiafiltrationCritical Care and Intensive Care MedicineEchinocandinsLipopeptides03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCaspofunginHumansMedicineIntensive care medicinebusiness.industryCritically illlcsh:Medical emergencies. Critical care. Intensive care. First aid030208 emergency & critical care medicinelcsh:RC86-88.9Invasive candidiasisContinuous venovenous hemodiafiltrationAcute Kidney Injurymedicine.diseaseInvasive candidiasisRenal Replacement TherapychemistryAdsorptionCaspofunginbusinessCritical Care
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Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris

2018

Abstract Candida spp. infections are a major cause of morbidity and mortality in critically ill patients. Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading worldwide. Since the first reports in 2009, many isolates across five continents have been identified as agents of hospital-associated infections. Independent and simultaneous outbreaks of C. auris are becoming a major concern for healthcare and scientific community. Moreover, laboratory misidentification and multi-drug-resistant profiles, rarely observed for other non-albicans Candida species, result in difficult eradication and frequent therapeutic failures of C. auris infections. The aim of this review…

0301 basic medicineSettore MED/07 - Microbiologia E Microbiologia Clinicamedicine.medical_specialty030106 microbiologySettore MED/41 - AnestesiologiaVirulenceAntimicrobial resistanceCritical Care and Intensive Care MedicineMicrobiology03 medical and health sciencesInvasive fungal infectionAntibiotic resistanceEpidemiologymedicineCandidaResistance (ecology)business.industryCritically illlcsh:Medical emergencies. Critical care. Intensive care. First aidCandidemiaOutbreakAntifungal resistancelcsh:RC86-88.9Candida aurisCandida sppC. aurisC. auris Candida Candidemia Invasive fungal infection Antimicrobial resistance Antifungal resistancebusinessJournal of Intensive Care
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The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

2016

Abstract Staphylococcal toxic shock syndrome (TSS) is most frequently produced by TSS toxin-1 (TSST-1) and Staphylococcal enterotoxin B (SEB), and only rarely by enterotoxins A, C, D, E, and H. Various clinical pictures can occur depending on severity, patient age and immune status of the host. Severe forms, complicated by sepsis, are associated with a death rate of 50-60%. The case of a Caucasian female infant, aged seven weeks, hospitalized with a diffuse skin rash, characterized as allergodermia, who initially developed TSS with axillary intertrigo, is reported. TSS was confirmed according to 2011 CDC criteria, and blood cultures positive for Methicillin-sensitive Staphylococcus aureus (…

0301 basic medicinemedicine.medical_specialtyIntertrigogenetic structuresmedicine.drug_classAntibioticsCase Reportmedicine.disease_causetssSepsis03 medical and health sciences0302 clinical medicine030225 pediatricsInternal medicinemedicineAcidosisRC86-88.9business.industryMortality rateMedical emergencies. Critical care. Intensive care. First aidstaphylococcal toxic shock syndromebacterial infections and mycosesmedicine.diseaseRash030104 developmental biologyStaphylococcus aureusSuperinfectionmedicine.symptombusinessmanagementThe Journal of Critical Care Medicine
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Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review

2021

Abstract Background The mortality of critically ill patients with COVID-19 is high, particularly among those receiving mechanical ventilation (MV). Despite the high number of patients treated worldwide, data on respiratory mechanics are currently scarce and the optimal setting of MV remains to be defined. This scoping review aims to provide an overview of available data about respiratory mechanics, gas exchange and MV settings in patients admitted to intensive care units (ICUs) for COVID-19-associated acute respiratory failure, and to identify knowledge gaps. Main text PubMed, EMBASE, and MEDLINE databases were searched from inception to October 30, 2020 for studies providing at least one v…

ARDSmedicine.medical_specialtyCritical Illnessmedicine.medical_treatmentReviewRespiratory physiologyCritical Care and Intensive Care MedicineHypoxemia03 medical and health sciencesMechanical ventilation0302 clinical medicineIntensive careFraction of inspired oxygenmedicineHumansIntensive care unitMechanical ventilation.Positive end-expiratory pressureMechanical ventilationRespiratory Distress SyndromeIntensive care unitsCoronavirus disease 2019Acute respiratory distress syndromebusiness.industrylcsh:Medical emergencies. Critical care. Intensive care. First aidCOVID-19030208 emergency & critical care medicinelcsh:RC86-88.9medicine.diseaseRespiration Artificial030228 respiratory systemEmergency medicineRespiratory Mechanicsmedicine.symptombusinessCohort studyCritical Care
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Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: Insights from the LUNG SAFE study

2020

Abstract Background Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence o…

ARDSmedicine.medical_treatment030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineHyperoxemiaHypoxemialaw.inventionHypoxemia0302 clinical medicinelawFraction of inspired oxygenOxygen therapyPrevalenceMedicineHypoxiaAcute respiratory distress syndrome; Hyperoxemia; Hyperoxia; Hypoxemia; Hypoxia; Invasive mechanical ventilation; Mortality; Oxygen therapy;Respiratory Distress SyndromeHyperbaric OxygenationAcute respiratory distress syndromeRespirationlcsh:Medical emergencies. Critical care. Intensive care. First aidHyperoxemiaIntensive care unitIntensive Care UnitsAnesthesiaArtificialmedicine.symptomHumanArtificial ventilationAcute respiratory distress syndrome; Hyperoxemia; Hyperoxia; Hypoxemia; Hypoxia; Invasive mechanical ventilation; Mortality; Oxygen therapyIntensive Care UnitHyperoxiaNO03 medical and health sciencesIntensive careSettore MED/41 - ANESTESIOLOGIAHumansInvasive mechanical ventilationMortalitybusiness.industryResearchRespiratory Distress Syndrome Adultlcsh:RC86-88.9medicine.diseaseOxygen therapyRespiration Artificialrespiratory tract diseasesOxygenlnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]030228 respiratory systembusiness
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Acute cholecystitis during COVID-19 pandemic: a multisocietary position statement

2020

AbstractFollowing the spread of the infection from the new SARS-CoV2 coronavirus in March 2020, several surgical societies have released their recommendations to manage the implications of the COVID-19 pandemic for the daily clinical practice. The recommendations on emergency surgery have fueled a debate among surgeons on an international level.We maintain that laparoscopic cholecystectomy remains the treatment of choice for acute cholecystitis, even in the COVID-19 era. Moreover, since laparoscopic cholecystectomy is not more likely to spread the COVID-19 infection than open cholecystectomy, it must be organized in such a way as to be carried out safely even in the present situation, to gu…

Acute cholecystitis; COVID-19 pandemic; Emergency surgery; New coronavirus; Position statement; Betacoronavirus; COVID-19; Cholecystectomy; Cholecystitis Acute; Coronavirus Infections; Humans; Infection Control; Pandemics; Pneumonia Viral; SARS-CoV-2; Societies Medical; Practice Guidelines as Topicmedicine.medical_treatmentCholecystitis AcutePosition statement030230 surgery0302 clinical medicinePandemicCholecystitisInfection control030212 general & internal medicineViralSocieties Medicallcsh:Medical emergencies. Critical care. Intensive care. First aidPractice Guidelines as TopicEmergency MedicineEmergency surgeryAcute cholecystitis Emergency surgery COVID-19 pandemic New coronavirus Position statementCoronavirus InfectionsHumanPosition statementmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia Virallcsh:SurgeryCOVID-19 pandemicNew coronaviruAcuteAcute cholecystitiacute cholecystitis; COVID-19 pandemic; emergency surgery; Nnew coronavirus; position statement; betacoronavirus; cholecystectomy; cholecystitis acute; coronavirus infections; humans; infection control; pandemics; pneumonia viral; societies medical; practice guidelines as topicNO03 medical and health sciencesBetacoronavirusEmergency surgeryMedicalmedicineAcute cholecystitisHumansCholecystectomyPandemicsAcute cholecystitis; COVID-19 pandemic; Emergency surgery; New coronavirus; Position statement; Betacoronavirus; Cholecystectomy; Cholecystitis Acute; Coronavirus Infections; Humans; Infection Control; Pandemics; Pneumonia Viral; Societies Medical; Practice Guidelines as TopicInfection ControlBetacoronaviruPandemicbusiness.industrySARS-CoV-2Coronavirus InfectionGeneral surgeryCOVID-19New coronavirusPneumonialcsh:RD1-811lcsh:RC86-88.9Acute cholecystitisSettore MED/18 - Chirurgia GeneraleInvasive surgeryCommentarySurgeryCholecystectomybusinessSocietiesWorld Journal of Emergency Surgery
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Procalcitonin levels in candidemia versus bacteremia: a systematic review

2019

Background Procalcitonin (PCT) is a biomarker used to assess systemic inflammation, infection, and sepsis and to optimize antimicrobial therapies. Its role in the in the differential diagnosis between candidemia and bacteremia is unclear. The aim of this systematic review was to summarize the current evidence about PCT values for differentiating candidemia from bacteremia. Methods PubMed and EMBASE were searched for studies reporting data on the diagnostic performance of serum PCT levels in intensive care unit (ICU) or non-ICU adult patients with candidemia, in comparison to patients with bacteremia. Results We included 16 studies for a total of 45.079 patients and 785 cases of candidemia. …

AdultMaleCalcitoninmedicine.medical_specialtyLetterBacteremiaCritical Care and Intensive Care MedicineProcalcitoninlaw.inventionSepsis03 medical and health sciences0302 clinical medicineBiomarker; Candida; Candidemia; Fungal; Fungi; PCT; Procalcitonin; SepsislawSecondary analysisSepsisparasitic diseasesmedicineHumansIntensive care medicineCandidaAdult patientsbusiness.industryResearchlcsh:Medical emergencies. Critical care. Intensive care. First aidFungiCandidemia030208 emergency & critical care medicinelcsh:RC86-88.9Biomarkermedicine.diseasebacterial infections and mycosesIntensive care unitFungalBacteremiaBiomarker (medicine)FemaleDifferential diagnosisbusinessPCTProcalcitoninhormones hormone substitutes and hormone antagonistsBiomarkersCritical Care
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Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis o…

2018

Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF…

AdultMaleDiabetes mellituLUNG SAFEOrgan Dysfunction Scoreshumanoslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Socio-culturaleOrgan Dysfunction ScoreDiabetes ComplicationsDiabetes mellituspuntuaciones de disfunción orgánicaRisk FactorsDiabetes Complicationestudios prospectivosHumansfactores de riesgoProspective StudiesHospital MortalityHypoxiamediana edadAcute hypoxemic respiratory failureAgedRespiratory Distress SyndromeancianoAcute respiratory distress syndromeResearchRespirationrespiraciónRespiratory Distress Syndrome Adultlcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RC86-88.9Middle AgedRespiration Artificialinsuficiencia respiratoriaAcute hypoxemic respiratory failure; Acute respiratory distress syndrome; Diabetes mellitus; LUNG SAFEProspective StudieArtificialAcute hypoxemic respiratory failure; Acute respiratory distress syndrome; Diabetes mellitus; LUNG SAFE; Aged; Diabetes Complications; Diabetes Mellitus; Female; Hospital Mortality; Humans; Hypoxia; Male; Middle Aged; Organ Dysfunction Scores; Prospective Studies; Respiration Artificial; Respiratory Distress Syndrome Adult; Respiratory Insufficiency; Risk FactorsFemaleRespiratory Insufficiencymortalidad hospitalariacomplicaciones de la diabetesHuman
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Vitamin D serum levels in multiorgan failure critically ill patients undergoing continuous renal replacement therapies

2020

Introduction Severe vitamin D deficiency in critically ill patients is linked to mortality. There are no scientific data regarding vitamin D status in critically ill patients undergoing continuous renal replacement therapies. Material and methods We aimed to measure vitamin D serum levels in critically ill patients with multi-organ failure undergoing continuous renal replacement therapies. Vitamin D serum measurements in 12-hour time intervals were performed in 20 patients undergoing continuous renal replacement therapies through continuous veno-venous haemodiafiltration (the study group). The results were then compared with the historical control group (20 patients without renal replacemen…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentcontinuous renal replacement therapyvitamin DCritical Care and Intensive Care MedicineSeverity of Illness IndexGastroenterologyvitamin D deficiencyAnesthesiologyInternal medicineIntensive caremedicineVitamin D and neurologyHumanscritical illnessRD78.3-87.3Renal replacement therapycritical illness.intensive careRC86-88.9Critically illbusiness.industryAcute kidney injuryMedical emergencies. Critical care. Intensive care. First aidGeneral MedicineMiddle AgedVitamin D Deficiencymedicine.diseaseMultiorgan failureAnesthesiology and Pain Medicineacute kidney injuryCase-Control StudiesCritical illnessbusinessAnaesthesiology Intensive Therapy
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Extravascular Lung Water Does Not Increase in Hypovolemic Patients after a Fluid-Loading Protocol Guided by the Stroke Volume Variation

2012

Introduction. Circulatory failure secondary to hypovolemia is a common situation in critical care patients. Volume replacement is the first option for the treatment of hypovolemia. A possible complication of volume loading is pulmonary edema, quantified at the bedside by the measurement of extravascular lung water index (ELWI). ELWI predicts progression to acute lung injury (ALI) in patients with risk factors for developing it. The aim of this study was to assess whether fluid loading guided by the stroke volume variation (SVV), in patients presumed to be hypovolemic, increased ELWI or not.Methods. Prospective study of 17 consecutive postoperative, fully mechanically ventilated patients dia…

Article Subjectbusiness.industrylcsh:Medical emergencies. Critical care. Intensive care. First aidCardiac indexHemodynamicslcsh:RC86-88.9Stroke volumeLung injuryCritical Care and Intensive Care MedicinePulmonary edemamedicine.diseaseHypovolemiaAnesthesiaClinical StudymedicineSinus rhythmmedicine.symptomComplicationbusinessCritical Care Research and Practice
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