Search results for "REAGENT"

showing 10 items of 699 documents

ChemInform Abstract: Intramolecular Michael Reaction of tert-Butylsulfinyl Ketimines: Asymmetric Synthesis of 3-Substituted Indanones.

2012

The reaction proceeds in the presence of the Ruppert—Prakash reagent (Tms-CF3) with either TBAT or TBAF as a base.

ChemistryIntramolecular forceReagentMichael reactionEnantioselective synthesisGeneral MedicineBase (exponentiation)Medicinal chemistryChemInform
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Sodium-mediated manganation: direct mono- and dimanganation of benzene and synthesis of a transition-metal inverse-crown complex.

2007

Inside out approach: Twofold deprotonation of benzene by a sodium monoalkyl bisamido manganate(II) reagent derived from BuNa, 2,2,6,6-tetramethylpiperidine, and Mn(CH2SiMe3)2 has produced the first inverse-crown complex in which the transition-metal atoms are incorporated in the host (see X-ray structure, blue N, green Na, purple Mn). Variable-temperature magnetization measurements show that the complex is antiferromagnetic.

ChemistryMetalationSodiumManganateInorganic chemistrychemistry.chemical_elementGeneral ChemistryAlkali metalCatalysischemistry.chemical_compoundCrystallographyDeprotonationTransition metalReagentBenzeneAngewandte Chemie (International ed. in English)
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Fluorinated heterocyclic compounds. A photochemical synthesis of 3-amino-5-perfluoroaryl-1,2,4-oxadiazoles

2001

Abstract A photochemical methodology for the synthesis of 3-amino- (or 3- N -substituted amino) 5-pentafluorophenyl-1,2,4-oxadiazoles is reported. Irradiation of 3-pentafluorobenzoylamino-4-methyl-1,2,5-oxadiazole (Furazan) at 254 nm in methanol and in the presence of ammonia, primary or secondary aliphatic amines produces 3-amino-, 3-( N -alkylamino)-, 3-( N , N -dialkylamino)-5-pentafluorophenyl-1,2,4-oxadiazoles. The photoreaction follows the fragmentation pattern of the furazan ring with the extrusion of acetonitrile and the formation of a counterpart fragment which the nitrogen nucleophile will capture. Depending on the nature of the reagent, displacement of a fluoride anion at the C(5…

ChemistryOrganic ChemistryRing (chemistry)PhotochemistryFurazanBiochemistrySolventchemistry.chemical_compoundNucleophileReagentDrug DiscoveryMoietyMethanolAcetonitrileTetrahedron
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Catalytic Enantioselective α-Oxysulfonylation of Ketones Mediated by Iodoarenes

2008

The alpha-oxysulfonylation of ketones catalysed by enantioenriched iodoarenes using mCPBA as stoichiometric oxidant is reported to give useful synthetic intermediates in good yield and modest enantioselectivity. We believe this to be the first report of an enantioselective organocatalytic reaction involving hypervalent iodine reagents which should open up a new field for enantioselective organocatalysis of oxidation reactions.

ChemistryOrganocatalysisReagentYield (chemistry)Organic ChemistryEnantioselective synthesisHypervalent moleculeOrganic chemistryPhysical and Theoretical ChemistryRedoxStoichiometryCatalysisEuropean Journal of Organic Chemistry
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Benzothiete, a Versatile Reagent in Heterocyclic Syntheses

1996

ChemistryReagentCombinatorial chemistryJournal f�r Praktische Chemie/Chemiker-Zeitung
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ChemInform Abstract: Benzothiete, a Versatile Reagent in Heterocyclic Syntheses

2010

ChemistryReagentGeneral MedicineCombinatorial chemistryChemInform
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ChemInform Abstract: Cyclopentadienyldicarbonylferrates ([C5H5(CO)2Fe]M, M: Na, K): Reagents with Various Synthetic Applications

2010

ChemistryReagentGeneral MedicineCombinatorial chemistryChemInform
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ChemInform Abstract: Synthesis of 5-Substituted α,β-Butenolides by Iron-Promoted Intramolecular Cyclocarbonylation: Addition of Organometallic Reagen…

2010

ChemistryReagentIntramolecular forceOrganic chemistryGeneral MedicineChemInform
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Cyclopentadienyldicarbonylferrates ([C5H5(CO)2Fe]M, M = Na, K): Reagents with various synthetic applications

1997

ChemistryReagentNuclear chemistryJournal für Praktische Chemie/Chemiker-Zeitung
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A Novel Approach to Dihydropyrrolones from Iron-Substituted α,β-Unsaturated Imines and Organolithium and Grignard Reagents: Developments, Mechanisms …

2000

Reactions of N-sulfonylimines, derived from Cp(CO)2Fe-substituted (Z)-enals and benzenesulfonamide, with Grignard or organolithium reagents furnish N-sulfonyldihydropyrrolones. When N-sulfinylimines and organometallic reagents are used, unprotected α,β-unsaturated γ-lactams are formed exclusively. Recent mechanistic studies and diastereoselective variations for the synthesis of chiral 5-substituted dihydropyrrolones from iron-substituted azadienes are discussed here.

ChemistryReagentOrganic Chemistrychemistry.chemical_elementLithiumStereoselectivityPhysical and Theoretical ChemistryCombinatorial chemistryEuropean Journal of Organic Chemistry
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