Search results for "REGIONS"

showing 10 items of 1521 documents

Regulation of tartrate metabolism by TtdR and relation to the DcuS–DcuR-regulated C4-dicarboxylate metabolism of Escherichia coli

2009

Escherichia coli catabolizes l-tartrate under anaerobic conditions to oxaloacetate by the use of l-tartrate/succinate antiporter TtdT and l-tartrate dehydratase TtdAB. Subsequently, l-malate is channelled into fumarate respiration and degraded to succinate by the use of fumarase FumB and fumarate reductase FrdABCD. The genes encoding the latter pathway (dcuB, fumB and frdABCD) are transcriptionally activated by the DcuS–DcuR two-component system. Expression of the l-tartrate-specific ttdABT operon encoding TtdAB and TtdT was stimulated by the LysR-type gene regulator TtdR in the presence of l- and meso-tartrate, and repressed by O2 and nitrate. Anaerobic expression required a functional fn…

OperonBiologymedicine.disease_causeMicrobiologyAntiportersSubstrate SpecificityOperonEscherichia colimedicinePromoter Regions GeneticTartratesEscherichia coliPsychological repressionHydro-LyasesRegulator geneNitratesEscherichia coli ProteinsPromoterGene Expression Regulation BacterialFumarate reductaseDNA-Binding ProteinsOxygenGlucoseBiochemistryDehydrataseFumaraseProtein KinasesTranscription FactorsMicrobiology
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The Streptomyces coelicolor dnaK operon contains a second promoter driving the expression of the negative regulator hspR at physiological temperature

2006

HspR (heat shock protein regulator) acts as a negative regulator of different genes in many bacteria. In Streptomyces coelicolor hspR gene is part and the transcriptional repressor of the dnaK operon which encodes the DnaK, GrpE, DnaJ chaperone machines and HspR itself. Our experiments led us to the discovery of a second promoter, internal to dnaK operon, located upstream hspR gene. Transcription from this promoter was detected at 30 degrees C indicating that hspR could play a key physiological role.

OperonMolecular Sequence Datagenetic processesRegulatorStreptomyces coelicolorBiochemistryMicrobiologyheat shock responseBacterial ProteinsTranscription (biology)Heat shock proteinOperonGeneticsHSP70 Heat-Shock ProteinsHeat shockPromoter Regions GeneticMolecular BiologyGeneHeat-Shock ProteinsGeneticsBase SequencebiologyReverse Transcriptase Polymerase Chain ReactionStreptomyces coelicolorTemperatureGene Expression Regulation BacterialGeneral Medicinebiology.organism_classificationRepressor ProteinshspRChaperone (protein)biological sciencesbiology.proteinbacteriaArchives of Microbiology
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Characterization of the CtsR stress response regulon in Lactobacillus plantarum.

2010

ABSTRACT Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the Δ ctsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of the ctsR - clpC operon and hsp1 .

OperonMutantBiology[ SDV.MP.BAC ] Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyMicroscopy Atomic ForceMicrobiologyRegulonMicrobiologylaw.invention03 medical and health sciencesBacterial ProteinslawGene RegulationPromoter Regions GeneticMolecular BiologyGeneHeat-Shock Proteins030304 developmental biologyGenetics0303 health sciences030306 microbiologyReverse Transcriptase Polymerase Chain ReactionTemperaturePromoterGene Expression Regulation Bacterialbiology.organism_classificationPhenotype[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyRepressor ProteinsRegulonRecombinant DNALactobacillus plantarumProtein BindingLactobacillus plantarum
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Calibration of the RPC charge readout in the ARGO-YBJ experiment

2012

""The charge readout of Resistive Plate Chambers (RPCs) is implemented in the ARGO-YBJ experiment to measure the charged particle density of the shower front up to 10^4\\\/m^2, enabling the study of the primary cosmic rays with energies in the ''knee'' region. As the first time for RPCs being used this way, a telescope with RPCs and scintillation detectors is setup to calibrate the number of charged particles hitting a RPC versus its charge readout. Air shower particles are taken as the calibration beam. The telescope was tested at sea level and then moved to the ARGO-YBJ site for coincident operation with the ARGO-YBJ experiment. The charge readout shows good linearity with the particle de…

Optical telescopesNuclear and High Energy PhysicsPhysics::Instrumentation and DetectorsCamere a Piastre Resistive (RPC)Resistive plate chamberAstrophysics::High Energy Astrophysical PhenomenaCosmic raylaw.inventionTelescopeSettore FIS/05 - Astronomia E AstrofisicaOpticslawCoincidentAir showersCalibrationSea levelInstrumentationParticle densitiesCosmic raysResistive Plate Chambers Charge read-out Extended Air ShowersPhysicsAir showers Charge readout Dynamic range Knee regions Particle densities Resistive plate chambers; Calibration Charged particles Cosmic rays Experiments Optical telescopes Sea level Telescopes; Particle spectrometersResistive touchscreenScintillationDynamic rangeCharge readoutParticle spectrometersbusiness.industryCharged particlesSettore FIS/01 - Fisica SperimentaleAstrophysics::Instrumentation and Methods for AstrophysicsCharged particleAir showerCalibrazione della Risposta Analogica di RPCKnee regionsLettura Analogica di RPCCalibrationResistive plate chambersbusinessExperimentsTelescopes
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Influence of formalin fixation on the biomechanical properties of human diaphyseal bone.

2010

Owing to the lack of fresh human bones, formalin-fixed specimens are frequently used in biomechanical testing. However, formalin fixation is assumed to affect the biomechanical properties of bone. The aim of this study was to compare axial and torsional stiffness and bone mineral density in fresh and embalmed human bones. The subtrochanteric regions of 12 pairs of fresh human femora were randomised into two groups for paired comparison. After bone mineral density measurement, one group was preserved in 4% formalin. After 6 weeks, bone mineral density was remeasured and each specimen underwent axial and torsional loading. The formalin group showed significant higher stiffness values for tors…

OrthodonticsBone mineralChemistryBiomedical EngineeringPaired comparisonStiffnessHuman boneFormalin fixedmusculoskeletal systemBiomechanical testingbody regionsFixativesElastic ModulusFormaldehydemedicineHumansFemurStress Mechanicalmedicine.symptomCadaveric spasmBiomedizinische Technik. Biomedical engineering
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A comparative evaluation between dermatoglyphic patterns and different terminal planes in primary dentition

2018

Background To assess the correlation between different dermatoglyphic patterns with the terminal planes in deciduous dentition. Material and methods 300 children who are 3-6 years old with complete primary dentition were recruited and the pattern of molar terminal plane was recorded in the proforma. Finger prints of the distal phalanges of these subjects were recorded using ink and roller method and were analysed for the finger print pattern by a forensic specialist. The pattern were classified based on classification given by Galton. The finger ridge counts were also measured. Results Ulnar loop pattern was the most predominant dermatoglyphic pattern. Absence of arch pattern in ring and li…

OrthodonticsDentitionResearchOrthodontics030206 dentistryPhalanxBiology:CIENCIAS MÉDICAS [UNESCO]Ridge (differential geometry)Plane (Unicode)body regions03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureTerminal (electronics)UNESCO::CIENCIAS MÉDICASRing fingermedicineDermatoglyphicsGeneral Dentistry030217 neurology & neurosurgeryWhorl (botany)
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Footwear outsole temperature may be more related to plantar pressure during a prolonged run than foot temperature.

2021

Objective. The temperature of the sole of the foot has been suggested as an alternative to the measurement of plantar pressure during running despite the scarce evidence about their relationship. The temperature of the footwear outsole could also be representative of plantar pressure distribution due to its less multifactorial dependence. The aim of the study was to determine if plantar pressure during a prolonged run could be related to plantar temperature, either of the sole of the foot or the footwear outsole.Approach. Thirty recreational runners (15 males and 15 females) performed a 30 min running test on a treadmill. Thermographic images of the sole of the foot and the footwear outsole…

OrthodonticsMalePhysiologybusiness.industryFootPlantar pressureForefootBiomedical EngineeringBiophysicsTemperatureBiomechanical PhenomenaRunningShoesbody regionsThermographyPhysiology (medical)MedicineHumansFemaleTreadmillbusinesshuman activitiesFoot (unit)Physiological measurement
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Assessment of the Elastographic and Electromyographic of Pelvic Floor Muscles in Postmenopausal Women with Stress Urinary Incontinence Symptoms

2021

Background. Shear wave elastography is an effective method for studying the condition of various musculoskeletal soft tissues. The primary aim of this study was the objective elastographic and electromyographic assessment of the pelvic floor during the rest and contraction of the pelvic floor muscles (PFM) in postmenopausal women. Methods. This was a prospective observational study that was carried out at the University Hospital in Wroclaw, Poland, between January 2017 and December 2019. Patients. The target group of the study included postmenopausal women with stress urinary incontinence. The primary outcomes were the features of the elastographic assessment of the pelvic floor during rest…

OrthodonticsShear wave elastographyelastographyMedicine (General)Pelvic floorPostmenopausal womenmedicine.diagnostic_testbusiness.industryClinical BiochemistrySoft tissuepostmenopausal womenUrinary incontinenceelastography; stress urinary incontinence; surface electromyography; postmenopausal womensurface electromyographystress urinary incontinenceArticlebody regionsUrethramedicine.anatomical_structureR5-920Inclusion and exclusion criteriamedicineElastographymedicine.symptombusinessDiagnostics
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Multicentric, multifocal, and recurrent osteoid osteoma of the hip: first case report.

2019

Abstract Background Osteoid osteoma is a benign bone-forming tumour, which very unfrequently has multifocal or multicentric presentation. We report the first known case of a multicentric, multifocal and recurrent osteoid osteoma treated using radiofrequency ablation. Case presentation A 39-year-old man with two-year history of left hip pain was admitted at our Institution. The pain was more intense during the night and partially relieved by salicylates. Pelvis CT demonstrated two lytic lesions (8 and 7 mm, respectively) with surrounding sclerotic reactive bone, both with a central focal area of high attenuation, located in the femoral neck and along the anterior portion of the acetabulum, r…

Osteoid osteomamusculoskeletal diseasesAdultMalemedicine.medical_specialtylcsh:Diseases of the musculoskeletal systemRadiofrequency ablationBiopsyOsteoma OsteoidBone NeoplasmsCase Reportlaw.inventionLesion03 medical and health sciences0302 clinical medicineRheumatologylawMedicineHumansOrthopedics and Sports MedicineComputed tomographyPelvisFemoral neck030203 arthritis & rheumatology030222 orthopedicsRadiofrequency AblationHipmedicine.diagnostic_testbusiness.industryFemur NeckMagnetic resonance imagingAcetabulummedicine.diseaseAcetabulumMagnetic Resonance ImagingPosterior columnbody regionsmedicine.anatomical_structureTreatment OutcomeOsteoid osteomaRetreatmentRadiologylcsh:RC925-935medicine.symptomNeoplasm Recurrence LocalbusinessTomography X-Ray ComputedBMC musculoskeletal disorders
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A rare case of peri-implant distal radius fracture☆

2021

A peri-implant fracture near the volar plate of distal radius represent a very rare injury. The main factor of this lesion is high energy trauma on the wrist. We report a case of a 61-year-old woman with a peri-implant fracture located just proximally to the plate and a fracture of the ulnar head that occurred after a simple fall. The patient was surgically treated by plate and screws removal. The fracture was fixed using a longer volar plate for the radial fracture and a plate for the head ulnar fracture. Different factors such as osteoporosis, BMI and screw position could influence the fracture pattern. However, considering growing use of plates for distal radius fracture fixation, the fr…

Osteoporosislcsh:SurgeryUlnar headCase ReportWristCritical Care and Intensive Care MedicinePeri-implant radius fracture03 medical and health sciencesFixation (surgical)0302 clinical medicineRare caseSettore MED/33 - Malattie Apparato LocomotoreMedicineOrthopedics and Sports MedicineWrist fractureOrthodontics030222 orthopedicsScrew positionbusiness.industry030208 emergency & critical care medicinelcsh:RD1-811medicine.diseaseRadius and ulna fracturebody regionsmedicine.anatomical_structureRadius hardware substitutionEmergency MedicineDistal radius fractureImplantbusinessTrauma Case Reports
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