Search results for "RESISTANCE"
showing 10 items of 3641 documents
The dialogue between east and west in the construction of gender photography as support of discourse and resistance
2018
En el marco de la globalización, en las nuevas narrativas de género se han producido cambios conceptuales con nuevos posicionamientos críticos y de resistencia. Mujeres creadoras de otras culturas, diferentes al mundo occidental, han trabajado para denunciar situaciones o poner en valor el empoderamiento de las mujeres como protagonistas de su destino. Y es en esta línea donde las mujeres artistas han aportado sus propuestas feministas y de resistencia. Los objetivos de este trabajo se centran en dos ejes conceptuales: a) analizar la situación de las mujeres en el contexto de los países islámicos y b), mostrar, a través del trabajo de fotógrafas procedentes de estos países, como se está con…
Implementering av elektroniske legemiddelkurven på et sykehus
2014
Masteroppgave i helse- og sosialinformatikk HSI 500 Universitetet i Agder 2014 Background: This rapport is a student project as a part of the final year program for master degree in Health and social Informatics at Agder University. The implementation of electronic prescribing systems in the health sector is a priority for both the public policy and for the management of hospitals. It is expected that such systems will increase the work capacity of the employees, improve information flow and reduce medication errors. Akershus University Hospital is the only hospital in Norway that has implemented an electronic prescribing system at the ward units. But implementation is seriously delayed com…
The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror
2021
Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic metabolic disorders, and insulin has been placed at the epicentre of its pathophysiological basis. However, the involvement of impaired alpha (α) cell function has been recognized as playing an essential role in several diseases, since hyperglucagonemia has been evidenced in both Type 1 and T2DM. This phenomenon has been attributed to intra-islet defects, like modifications in pancreatic α cell mass or dysfunction in glucagon’s secretion. Emerging evidence has shown that chronic hyperglycaemia provokes changes in the Langerhans’ islets cytoarchitecture, including α cell hyperplasia, pancreatic beta (β) cell dedifferentiati…
Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)
2016
Bacillus thuringiensis Cry3Aa and Cry3Ca proteins have been reported to be toxic against the African sweetpotato pest Cylas puncticollis. In the present work, the binding sites of these proteins in C. puncticollis brush border vesicles suggest the occurrence of different binding sites, but only one of them is shared. Our results suggest that pest resistance mediated by alteration of the shared Cry-receptor binding site might not render both Cry proteins ineffective.
The Measurement of Large Strains Using Electrical Resistance Strain Gages
2011
It is well known that in the range of large strains, the electrical resistance strain gages have a nonlinear behavior, that is the variation of electrical resistance is a nonlinear function of the strain applied to the strain gage, which means that the gage factor K is not constant. Also, the Wheatstone bridge has a nonlinear behavior at large strains. Usually the two nonlinearities have opposite effects, therefore the overall nonlinearity decreases. This article presents an overview of the behavior of strain gages subject to large strains and of the corrections to account for nonlinearities of both the strain gage and the Wheatstone bridge.
Glucose lowering and anti-atherogenic effects of incretin-based therapies: GLP-1 analogues and DPP-4-inhibitors
2009
Type 2 diabetes is a chronic, progressive disease with a multi-faceted pathophysiology. Beyond the known defects of insulin resistance and beta-cell insufficiency, derangement of incretin hormones normally produced from the gut wall in response to food intake play an important role. In recent years, the 'incretin-based' therapies (IBTs) have been developed to address hyperglycemia through either mimicking the action of the endogenous incretin glucagon-like polypeptide (GLP-1) (GLP-1 receptor agonists) or by inhibiting the activity of the enzyme that degrades GLP-1 (the dipeptyl peptidase-4 inhibitors).We reviewed available evidence on the glucose lowering and anti-atherogenic effects of IBT…
GLP-2 as Beneficial Factor in the Glucose Homeostasis in Mice Fed a High Fat Diet
2015
Glucagon like peptide-2 (GLP-2) is a gastrointestinal hormone released in response to dietary nutrients, which acts through a specific receptor, the GLP-2 receptor (GLP-2R). The physiological effects of GLP-2 are multiple, involving also the intestinal adaptation to high fat diet (HFD). In consideration of the well-known relationship between chronic HFD and impaired glucose metabolism, in the present study we examined if the blocking of the GLP-2 signaling by chronic treatment with the GLP-2R antagonist, GLP-2 (3-33), leads to functional consequences in the regulation of glucose metabolism in HFD-fed mice. Compared with animals fed standard diet (STD), mice at the 10th week of HFD showed hy…
Pituitary resistance to thyroid hormone action with preserved circadian rhythm of thyrotropin in a postmenopausal woman.
1992
We assessed the 24-h behavior of circulating TSH and the dopaminergic control on TSH release in a postmenopausal woman, who had elevated levels of serum thyroid hormones and an inappropriately high concentration of serum TSH, indicating pituitary resistance to thyroid hormone action. The patient was found to have a daily profile of serum TSH similar to that of normal subjects, except for the persistently elevated 24 h levels, suggesting that alterations in thyroid hormone negative feedback control did not affect substantially circadian TSH rhythm. The acute administration of a dopamine antagonist drug (metoclopramide) resulted in a markedly elevated peak of serum TSH, similar both in the mo…
Role of glutathione in Thiobencarb resistance in the European eel Anguilla anguilla.
2000
Glutathione-dependent defense against xenobiotic toxicity is a multifaceted phenomenon that has been well characterized in mammals. In the present study, eels of species Anguilla anguilla were exposed to 15 ppm of the herbicide thiobencarb (S-4-chlorobenzyl diethylthiocarbamate) for 96 h. Eels exposed to the pesticide were grouped in 24-h intervals according to their time of death, while surviving intoxicated eels constituted another group (live animals). Glutathione content (GSx, GSH, GSSG) was determined in liver and muscle tissues of the dead and live (intoxicated) animals and compared to control values (nonexposed eels). The fish that died before 96 h of exposure were considered suscept…
Heart in Hyperthyroidism
2019
Hyperthyroidism is a common endocrine disorder that produces important clinical consequences on the cardiovascular system. In overt hyperthyroidism the increase in left ventricular performance is predominantly sustained by an increased preload with enhanced left ventricular diastolic function and reduced systemic vascular resistance. The pattern of cardiovascular abnormalities is similar in subclinical and overt hypothyroidism, suggesting that a lesser degree of thyroid hormone deficiency may also affect the cardiovascular system. Untreated overt and subclinical hypothyroidism can lead to an increased risk of coronary heart disease (CHD), heart failure (HF), and cardiovascular mortality.