Search results for "RIP"
showing 10 items of 9780 documents
Cleavage of Ge–Ge and Sn–Sn Triple Bonds in Heavy Group 14 Element Alkyne Analogues (EAriPr4)2 (E = Ge, Sn; AriPr4 = C6H3-2,6(C6H3-2,6-iPr2)2) by Rea…
2016
The reactions of heavier group 14 element alkyne analogues (EAriPr4)2 (E = Ge, Sn; AriPr4 = C6H3-2,6-(C6H3-2,6-iPr2)2) with the group 6 transition-metal carbonyls M(CO)6 (M = Cr, Mo, W) under UV irradiation resulted in the cleavage of the E–E triple bond and the formation of the complexes {AriPr4EM(CO)4}2 (1–6), which were characterized by single crystal X-ray diffraction as well as by IR and multinuclear NMR spectroscopy. Single-crystal X-ray structural analyses of 1–6 showed that the complexes have a nearly planar rhomboid M2E2 core with three-coordinate group 14 atoms. The coordination geometry at the group 6 metals is distorted octahedral formed by four carbonyl groups as well as two br…
The synergistic effect exerted by the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide on triple negative breast canc er cells
2014
Triple-negative breast cancer (TNBC) is a subtype o f breast cancer, insensitive to endocrine therapy. Chemotherapy is the main form of treatment, but is accompanied by a high rate of recidivism. The sesquiterpene lactone Parthenolide (PN) exerts a cy totoxic effect on MDA-MB231 cells, a TNBC cell line (1), but was ineffective at low doses (2-5μM). This repr esents an obstacle for a therapeutic utilization of PN. We supposed, in line with other authors (2), that PN c auses a protective response, which at low doses pre vails on the cytotoxic effect. With the aim of inhibiting this protective effect we have shown that pre-trea tment of MDA-MB231 cells with SAHA (2-5μM), an histone deace tylat…
Producción de blastocistos diploides, heteroparentales a partir de pre-embriones tripronucleareshumanos procedentes de FIV e ICSI
2015
En Biomedicina, particularmente en el campo de reproducción humana asistida, la mejora de las técnicas implícitas, así como la puesta a punto de otras, requiere de la realización de estudios y ensayos previos con pre-embriones, preferiblemente de la misma especie, con potencial de desarrollo y que sean genéticamente normales. La disponibilidad y uso de estos pre-embriones no debe provocar conflictos éticos ni legales, no siendo, los pre-embriones humanos generados con una finalidad reproductiva la opción más inmediata. En la búsqueda de modelos pre-embrionarios humanos válidos, homólogos a aquéllos reproductivamente viables, presentamos el presente trabajo de tesis, cuyo objetivo principal …
Acid–base properties of functionalised tripodal polyamines and their interaction with nucleotides and nucleic acids
2010
Novel, highly positively charged tripodal polyamines with appended heterocyclic moieties revealed an intriguing panel of protonation species within the biologically relevant range. Studied compounds bind nucleotide monophosphates by mostly electrostatic interactions but only the imidazole analogue showed selectivity toward UMP in respect to other nucleotides. Strong binding of all the studied compounds to both ds-DNA and ds-RNA is to some extent selective toward the latter, showing rather rare RNA over DNA preference.
CCDC 942549: Experimental Crystal Structure Determination
2015
Related Article: Christina Lohoelter, Malte Brutschy, Daniel Lubczyk and Siegfried R. Waldvogel|2013|Beilstein J.Org.Chem.|9|2821|doi:10.3762/bjoc.9.317
Identification of mycorrhiza-regulated genes with arbuscule development-related expression profile
2004
Suppressive subtractive hybridisation was applied to the analysis of late stage arbuscular mycorrhizal development in pea. 96 cDNA clones were amplified and 81, which carried fragments more than 200 nt in size, were sequence analysed. Among 67 unique fragments, 10 showed no homology and 10 were similar to sequences with unknown function. RNA accumulation of the corresponding 67 genes was analysed by hybridisation of macro-arrays. The cDNAs used as probes were derived from roots of wild type and late mutant pea genotypes, inoculated or not with the AM fungus Glomus mosseae. After calibration, a more than 2.5-fold mycorrhiza-induced RNA accumulation was detected in two independent experiments…
Electronic Energy Meter Based on a Tunnel Magnetoresistive Effect (TMR) Current Sensor
2017
In the present work, the design and microfabrication of a tunneling magnetoresistance (TMR) electrical current sensor is presented. After its physical and electrical characterization, a wattmeter is developed to determine the active power delivered to a load from the AC 50/60 Hz mains line. Experimental results are shown up to 1000 W of power load. A relative uncertainty of less than 1.5% with resistive load and less than 1% with capacitive load was obtained. The described application is an example of how TMR sensing technology can play a relevant role in the management and control of electrical energy.
Tunnustuksen saaminen perheen sisäisessä adoptioprosessissa : sateenkaariperheiden kokemuksia adoptioneuvonnasta
2014
Tutkimuksessa tarkastellaan sateenkaariperheiden kokemuksia adoptioneuvonnasta perheen sisäisen adoption yhteydessä. Tutkimuksen kohteena on, miten tunnustuksen saaminen (tai sen puute) omalle perheidentiteetille näkyy adoptioneuvontatyössä. Tutkimusaineisto koostuu viiden informantin kirjoittamista kokemuksista perheen sisäisestä adoptioprosessista. Aineiston analyysimenetelmänä on käytetty teorialähtöistä sisällönanalyysiä. Tutkielmassa analysoidaan sateenkaariperheiden kokemuksia perheen sisäisestä adoptioprosessista Axel Honnethin tunnustuksen teorian ja sen sosiaalityön tulkintojen pohjalta. Tunnustuksen teoria antaa käsityksen siitä, miten keskeistä ihmisen identiteetin muodostumisen …
Schrift – Bild – Zeichen: Zum Titelkopf in der deutschen Minderheitspresse in Polen nach 1989
2012
Nagłówek gazety i czasopisma stanowi element rozpoznawczy danego medium i wspólnie z jego pierwszą stroną tworzy niejako jego wizytówkę. Za pomocą odpowiednich środków typograficznych, takich jak pismo, linia, płaszczyzna czy obraz, podkreślona zostaje wyjątkowość danej gazety/danego czasopisma, która wyróżnia ją/je spośród innych, równocześnie jednak przekazane zostają tu określone informacje. Zastosowany rodzaj i krój pisma jako odbierana zmysłowo za pomocy wzroku postać języka oddziałuje przy tym na odbiorcę podobnie jak obraz. Jak niektóre wyrazy zmieniają swe znaczenie w kontekście innych wyrazów, także słowo pisane może nabrać innego sensu w zależności od otaczających je obrazów. Takż…
Nadprzyrodzony charakter Pisma Świętego w nauczaniu Ojców Kościoła na przykładzie Orygenesa. Przyczynek do badań nad egzegezą patrystyczną
2015
What distinguishes the biblical books of Sacred Scripture from other compositions and works of literature is undoubtedly its supernatural character described in theology as inspiration. Still, the reflction of numerous centuries,beginning from the Church Fathers, has been necessary to formulate this specifi quantity of the biblical text as well as explain and classify it into proper categories corresponding with the contents of Sacred Scripture. A unique and unrepeatable role in this process was played by Origen, a priest and exegete of the turn of 2nd and 3 rd centuries, who among through his works paved the way for theology in reading Sacred Scripture as the genuine Word of God, respected…