Search results for "RME"
showing 10 items of 6748 documents
Revisiting the thiosemicarbazonecopper(II) reaction with glutathione. Activity against colorectal carcinoma cell lines.
2018
Thiosemicarbazones (TSCs), and their copper derivatives, have been extensively studied mainly due to the potential applications as antitumor compounds. A part of the biological activity of the TSC-CuII complexes rests on their reactivity against cell reductants, as glutathione (GSH). The present paper describes the structure of the [Cu(PTSC)(ONO2)]n compound (1) (HPTSC =pyridine-2-carbaldehyde thiosemicarbazone) and its spectroscopic and magnetic properties. ESI studies performed on the reaction of GSH with 1 and the analogous [{Cu (PTSC*)(ONO2)}2] derivative (2, HPTSC* =pyridine-2-carbaldehyde 4N-methylthiosemicarbazone) show the absence of peaks related with TSC-Cu-GSH species. However GS…
mHealth for the Monitoring of Brace Compliance and Wellbeing in Adolescents with Idiopathic Scoliosis: Study Protocol for a Feasibility Study
2021
Escoliosis idiopática del adolescente; Aplicación móvil; Eficacia del tratamiento Escoliosi idiopàtica de l'adolescent; Aplicació mòbil; Eficàcia del tractament Adolescent idiopathic scoliosis; Mobile application; Treatment effectiveness Attempts to optimize monitoring of brace adherence prescribed to adolescents with idiopathic scoliosis (IS) have generally relied on sensors. Sensors, however, are intrusive and do not allow the assessment of psychological and physical consequences of brace use that might underlie poor adherence. Mobile applications have emerged as alternatives to monitor brace compliance. However, the feasibility and utility of these app-based systems to assess key psychol…
Gender-related effect of clinical and genetic variables on the cognitive impairment in multiple sclerosis
2004
BACKGROUND: Cognitive impairment may occur at any time during the course of multiple sclerosis (MS), and it is often a major cause of disability in patients with the disease. The APOE-epsilon4 allele is the major known genetic risk factor for late onset familial and sporadic Alzheimer's Disease (AD), and it seems to be implicated in cognitive decline in normal elderly persons. OBJECTIVE: To investigate the clinical and genetic variables that can be associated with the cognitive decline in patients with MS. METHODS: Five-hundred and three patients with clinically definite MS underwent a battery of neuropsychological tests and, according to the number of failed tests, were divided into cognit…
Isolated, Subtle Neurological Abnormalities in Mild Cognitive Impairment Types.
2019
Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.To investigate the frequency of ISNA in different mild cognitive impairment (MCI) types and to evaluate for each MCI type, the cross-sectional relation between ISNA and white matter hyperintensities (WMH), lacunes, caudate atrophy, and ventricular enlargement.One thousand two hundred fifty subjects with different MCI types were included in the analysis and underwent brain magnetic resonance imaging. WMHs were assessed through two visual rating scales. Lacunes were also rated…
Modified nonsink equation for permeability estimation in cell monolayers: comparison with standard methods.
2014
Cell culture permeability experiments are valuable tools in drug development and candidate selection, but the monolayer preparation protocols and the calculations procedures can affect the permeability estimation. Hence, standardization and method suitability demonstration are necessary steps for using permeability data for regulatory and in vivo prediction purposes. Much attention is usually paid to experimental procedure validation and less to the mathematical analysis of the results although the standard equations used imply several assumptions that many times do not hold. The aim of this study was to use a simulation strategy to explore the performance of a new proposed modified nonsink…
La situazione originaria
2017
Nelle Lezioni di pedagogia fondamentale, curate dall'Autore, si tratta del primo capitolo della Seconda unità formativa, dal titolo Genesi del problema educativo e della riflessone pedagogica nei mondi della vita. Una analitica dell'esistenza umana.Scrive in avvio l'Autore: " Facciamo subito nostra quella che per la fenomenologia costituisce la prima regola per il pensiero: condurre la riflessione mossi dal criterio dell’evidenza . Ora, la prima evidenza che si offre quando s’inizia una riflessione – ed è quanto accade a noi che vogliamo ragionare di fenomeni educativi – è che c’è un soggetto, ci son dei soggetti che si pongono delle domande. C’è qualcosa, meglio qualcuno, un io sono che qu…
Giudizio penale di seconda istanza e giusto processo - Seconda edizione
2008
IL LAVORO SI OCCUPA DELLO STUDIO DEL PROCESSO PENALE DI APPELLO ALLA LUCE DELLA RIFORMA COSTITUZIONALE CHE HA INTRODOOTO IL "GIUSTO PROCESSO" NELL''ART.111. LO STUDIO SI PREFIGGE DI VERIFICARE LA COMPATIBILITA'' DEL SECONDO GIUDIZIO CON IL PRINCIPIO DEL CONTRADDITTORIO E DEGLI ALTRI CANONI FORNDAMENTALI DEL PROCESSO A VOCAZIONE ACCUSATORIA, VISTO L''INNEGABILE FISIONOIMIA DI MECCANISMO DI CRITICA DEL PRIMO GIUDIZIO, COME TALE CARTOLARE E NON ORALE. SI PROPONGOO SOLUZIONI NORMATIVE PER SUPERARE GLI ASPETTI DI FRIZIONE CON IL MODELLO DEL PROCESSO ACCUSATORIO ACCREDITATO IN COSTITUZIONE ALL''ART. 111.
3‐D CALCULATION OF ZERO‐COMPONENT FLUX IN THREE‐PHASE THREE‐COLUMN TRANSFORMER
1994
The paper discusses the problem of space distribution of zero‐component magnetic flux generated in three‐column transformer. For 3‐D magnetic field calculation the method of integral equations was used. The numerical calculations were made for physical model of the transformer and compared with experimental results. The accuracy of the calculations of the magnetic field, achieved in the work, proves that the modelling may be used as a computer aided designing tool.
Normes d'apprentissage et "pathologies" de la lecture
2017
International audience
Étude sur les réformes curriculaires par l'approche par compétences en Afrique
2009
Cette étude vise trois objectifs : réaliser un état des lieux des processus de réformes curriculaires en éducation de base en Afrique pour identifier les problèmes rencontrés, les résultats positifs et les "bonnes pratiques", aider les responsables des systèmes éducatifs à prendre des mesures pertinentes et accompagner les réformes et enfin aider les bailleurs de fonds à mieux comprendre les effets de leur aide et à mieux cibler les projets de réforme en termes de coût et d'efficacité à tous les niveaux des systèmes éducatifs impliqués.