Search results for "RPS"
showing 10 items of 249 documents
Lack of genetic association of neutral endopeptidase (NEP) with complex regional pain syndrome (CRPS)
2010
Complex regional pain syndrome (CRPS) is a condition that is characterized by severe pain and exaggerated neurogenic inflammation, which may develop after injury or surgery. Neurogenic inflammation is mediated by neuropeptides, such as calcitonin gene-related peptide (CGRP) and substance P (SP) that are released from nociceptors. Genetic factors may play a role in CRPS as was suggested by the occurrence of familial cases and several genetic association studies investigating mainly the human leukocyte antigen (HLA) system. Here we investigated the role of neutral endopeptidase (NEP), a key enzyme in neuropeptide catabolism. NEP dysfunction resulting in reduced inactivation of neuropeptides m…
Two-site ELISA for quantification of the terminal C5b-9 complement complex in plasma
1993
Abstract A quantitative ELISA procedure using monoclonal and polyclonal antibodies against neoantigens of the terminal C5b-9 complement complex has been developed. The ELISA was demonstrated to be both sensitive and reproducible. The normal range for C5b-9 determinations, defined as 2.5–97.5% interval of the values obtained in 76 healthy blood donors, was 3.12–10.3 AU/ml. The presence of rheumatoid factor did not affect the determination of C5b-9 as demonstrated by immunoabsorption studies.
Flow cytometric immunophenotyping: principles and pitfalls
1992
Within the last decade flow cytometry (FCM) has become an integral part of basic immunological research. Elaboration of this technology has been intensively stimulated by a rapidly growing sophistication in monoclonal antibody technology and vice versa. At present numerous applications are established that allow an increasingly detailed insight into the immune system, however, automation still must be considered the "cinderella of the arts". Thus, transition of this powerful approach from a basic to a routine clinical procedure is much more difficult than expected. Sufficient usage of flow cytometers still requires some knowledge of physics and its technical applications. Moreover, several …
Generation of monoclonal antibodies against human regulatory T cells.
2009
Abstract Natural CD4 + CD25 + Foxp3 + regulatory T cells (Tregs) control the activation of the immune system and therefore have become a major area of research in immunology. The generation of monoclonal antibodies against human Tregs offers the possibility to discover novel Treg-specific or Treg-associated surface markers and to identify targets for a therapeutic modulation of Tregs. Here we present a methodology optimized to efficiently induce and select mAb against human Tregs by repeated immunization of mice with Tregs from a single donor and a differential two-step flow cytometry-based hybridoma screening procedure.
Tradicionālā latviešu tautas tērpa krekli 19. un 20. gs.
1995
Both attention and prediction are necessary for adaptive neuronal tuning in sensory processing
2014
International audience; The brain as a proactive system processes sensory information under the top-down influence of attention and prediction. However, the relation between attention and prediction remains undetermined given the conflation of these two mechanisms in the literature. To evaluate whether attention and prediction are dependent of each other, and if so, how these two top-down mechanisms may interact in sensory processing, we orthogonally manipulated attention and prediction in a target detection task. Participants were instructed to pay attention to one of two interleaved stimulus streams of predictable/unpredictable tone frequency. We found that attention and prediction intera…
De chair et de marbre. La beauté des corps dans l’art grec ancien au British Museum
2016
International audience; La beauté des corps dans l'art grec ancien se célèbre au British Museum. Jusqu'au 5 juillet au British Museum, Londres. Plongé dans une quasi-obscurité, le visiteur découvre objets et statues brillant sous la lumière artificielle comme des diamants sur un écrin de velours : le Discobole - lanceur de disque créé par Myron au Ve siècle av. J.-C. -, le Doryphore - porteur de lance imaginé par son contemporain Polyclète - ou l'Aphrodite accroupie (statue hellénistique représentée ici par une copie romaine du IIe siècle ap. J.-C.). Ainsi se dévoile, dans la belle exposition « Definiting Beauty: the Body in Ancient Greek Art », qui rassemble originaux et copies, un réperto…
Jēkabs Ķīburis – folkloras vācējs, teicējs un interprets
2021
Maģistra darba uzmanības centrā ir līdz šim maz apzināta personība Latvijas kultūrvēsturē – bārtenieks Jēkabs Ķīburis. Darbā pētīta J. Ķībura loma Bārtai un Nīcai raksturīgās tradicionālās kultūras saglabāšanā un popularizēšanā, radot vienotu, hronoloģisku vēstījumu par viņa personību, dzīves gājumu un svarīgākajiem darbības virzieniem atbilstošajā sociālpolitiskajā un kultūrvēsturiskajā laiktelpā. Tiek skatītas mijsakarības starp J. Ķībura dzīves gājumu un viņa folkloras repertuāru, analizēts viņa apjomīgais folkloras vākums, kā arī viņa ieguldījums Bārtas etnogrāfiskā ansambļa vadīšanā un novada tautstērpu izpētē. Pētījuma noslēgumā skatīti J. Ķībura radīto iestudējumu iespējamie ierosmes…
Data Compression Approach for Long-Term Monitoring of Pavement Structures
2019
Pavement structures are designed to withstand continuous damage during their design life. Damage starts as soon as the pavement is open to traffic and increases with time. If maintenance activities are not considered in the initial design or considered but not applied during the service life, damage will grow to a point where rehabilitation may be the only and most expensive option left. In order to monitor the evolution of damage and its severity in pavement structures, a novel data compression approach based on cumulative measurements from a piezoelectric sensor is presented in this paper. Specifically, the piezoelectric sensor uses a thin film of polyvinylidene fluoride to sense the ener…
La première rencontre du corps malade en contexte de soins infirmiers : la relation de soin : une expérience ultime, du sensible au social
2016
Our study focuses on nursing care with a first approach based on human body and emotions through the teaching context in the sensitive hospital environment. The nursing student is a central point of our research as he lives a unique sensitive and interpersonal experience within his own body in a social setting imbued with symbolism. He perceives health care community through his five senses which inform and direct him, but also may destabilize him. We decided to base our study on the information and communication sciences thanks to a sensitive, sensorial and symbolic problematisation and through a multidisciplinary conceptualization based on different theoretical approaches, symbolic intera…