Search results for "RUN"
showing 10 items of 2820 documents
Trīsgadīgu bērnu runas attīstīšanas iespējas didaktiskajās spēlēs
2017
Darba nosaukums: „Trīsgadīgu bērnu runas attīstīšanas iespējas didaktiskajās spēlēs” Darba autore: Kristīne Možeiko Darba vadītāja: Mag.paed. Aija Kalve Darba mērķis: Pētīt trīsgadīgu bērnu runas attīstību didaktiskajās spēlēs. Hipotēze: Bērna runa didaktiskajās spēlēs tiks veicināta, ja: •izvēlētās didaktiskās spēles atbildīs vecumposmam; •spēļu saturs nodrošinās runas attīstību; •spēles tiks organizētas regulāri. Pētījuma uzdevumi: •analizēt pedagoģijas un psiholoģijas zinātnieku atziņas pirmsskolas vecuma bērnu dialogrunas attīstību. •noteikt trīsgadīgu bērnu dialogrunas attīstības vērtēšanas kritērijus. •Veikt pētījumu par 3-4 gadu vecu bērnu dialogrunas attīsttību. Darba struktūra- dar…
Vidējā pirmsskolas vecuma bērna valodas un runas prasmju sekmēšana didaktiskajās rotaļās
2017
Kvalifikācijas darbs izstrādāts par tēmu „Vidējā pirmsskolas vecuma bērna valodas un runas prasmju sekmēšana didaktiskajās rotaļās”. Darba autore: Madara Tūtare Darba vadītāja: Aija Kalve Kvalifikācijas darba mērķis: Pētīt pirmsskolēna runas attīstību didaktisko spēļu procesā. Hipotēze: Pirmsskolēna runa didaktiskajās spēlēs tiks sekmēta, ja: izvēlētās didaktiskās spēles atbilst bērna vecumposma īpatnībām; 1.didaktisko spēļu saturs ietver runas attīstīšanas iespējas; 2.didaktiskā spēle atbilst bērna interesēm un vajadzībām. Kvalifikācijas darba apjoms: kvalifikācijas darbam ir 2 nodaļas, 8 apakšnodaļas un 44 lapaspuses. Darbā tika iekļauti 6 attēli, 10 tabulas, tika izanalizēts 41teorētiska…
Treatment of Advanced Hormone Receptor-Positive (HR+) HER2-negative Breast Cancer
2019
AbstractThe article gives an overview of current treatment options for metastatic hormone receptor-positive and HER2-negative breast cancer. The focus is on combined therapies, e.g., with CDK4/6 inhibition compared with purely endocrine-based therapies in the pre- and postmenopause, presenting the latest study results. The addition of a CDK4/6 inhibitor to endocrine-based therapy with an aromatase inhibitor or fulvestrant leads to a marked improvement in progression-free survival and is independently beneficial whether palbociclib, ribociclib or abemaciclib is involved. The particular clinical status of inhibition of cyclin-dependent kinases argues for its use in the first-line treatment of…
Deklarācijas pie Konvencijas par starptautiskajiem preču pirkuma-pārdevuma līgumiem
2016
Šajā pētījumā apskatītas pie ANO Konvencijas par starptautiskajiem preču-pirkuma pārdevuma līgumiem izteiktās deklarācijas un atrunas. Starptautiskajām publiskajām tiesībām veltītajā darbā nodaļā aplūkoti atrunu un deklarāciju jēdzieni, to izteikšanas kārtība un nosacījumi, kā arī spēkā esamība un jo sevišķi Vīnes konvencijas par starptautisko līgumu tiesībām regulējums un ANO Starptautisko tiesību komisijas izstrādātais Ceļvedis darbā ar atrunām. Savukārt starptautiskajām privāttiesībām veltītā nodaļa izvērtē ANO Konvencijas par starptautiskajiem preču-pirkuma pārdevuma līgumiem nobeiguma noteikumos paredzētās deklarācijas un atrunas, apskatot katru tās veidu atsevišķi un izdarot secinājum…
Brevi considerazioni su piogge intense e potenzialità di produzione del deflusso superficiale in Sicilia
2013
Vengono presentati i metodi aggiornati per la stima delle precipitazioni intense massime annue di fissato tempo di ritorno in Sicilia. Dall‟osservazione della distribuzione spaziale dei parametri assunti nei modelli di stima emergono aree a maggior rischio riguardo l‟intensità di pioggia, qui commentate. Il richiamo a recenti studi che riguardano la produzione del deflusso superficiale a scala media annua o a scala di evento, consente di avanzare alcune considerazioni di tipo spaziale, con particolare attenzione all‟area del messinese, su questa importante propensione idrologica notoriamente fonte di dissesto idrogeologico e di pericolo alluvionale. The updated methods for the estimation of…
Deteriorated stabilization of walking in individuals with spastic cerebral palsy revealed by a simulated tripping perturbation
2014
Abstract. The aim of this study was to make use of a pr eviously introduced method of a simulated tripping perturbation to examine stability of walking in individuals with and with out cerebral palsy. This tripping perturbation is a forward-dynamics analys is, and it works so that in a subjec t-specific muscle-driven simulation of walking, created from experimental gait data, a force is applied to the swin g-foot, and resulting changes in the kinematics are observed. Here, changes in the fore-aft position of the trunk were analyzed. Subjects were 10 children with spastic diplegic cerebral palsy and eight un impaired children walking at their self-sel ected speed. Several tripping perturbati…
Fluxapyroxad Haptens and Antibodies for Highly Sensitive Immunoanalysis of Food Samples
2017
Fluxapyroxad is a new-generation carboxamide fungicide, with residues increasingly being found in food samples. Immunochemical assays have gained acceptance in food quality control as rapid, cost-effective, sensitive, and selective methods for large sample throughput and in situ applications. In the present study, immunoreagents to fluxapyroxad were obtained for the first time, and competitive immunoassays were developed for the sensitive and specific determination of fluxapyroxad residues in food samples. Two carboxyl-functionalized analogues of fluxapyroxad were prepared, and antibodies with IC50 values in the low nanomolar range were generated from both haptens, though a dissimilar respo…
Insights into the relationships of Palearctic and Nearctic lymnaeids (Mollusca : Gastropoda) by rDNA ITS-2 sequencing and phylogeny of stagnicoline i…
2003
Fascioliasis by Fasciola hepatica is the vector-borne disease presenting the widest latitudinal, longitudinal and altitudinal distribution known. F. hepatica shows a great adaptation power to new environmental conditions which is the consequence of its own capacities together with the adaptation and colonization abilities of its specific vector hosts, freshwater snails of the family Lymnaeidae. Several lymnaeid species only considered as secondary contributors to the liver fluke transmission have, however, played a very important role in the geographic expansion of this disease. Many of them belong to the so-called "stagnicoline" type group. Stagnicolines have, therefore, a very important a…
The sarculator stratified prognosis of patients with high-risk soft tissue sarcomas (STS) of extremities and trunk wall treated with perioperative ch…
2017
11016 Background: Patients with extremity and trunk wall STS with high malignancy grade and size larger than 5cm are considered at high risk of death, but in fact this risk varies broadly depending on histologic subtype and size. The Sarculator, a nomogram for STS, can improve prognostic assessment of these patients. This tool was evaluated for stratifying risk of distant metastasis (DM) and overall survival (OS) in a RCT investigating perioperative chemotherapy. Methods: High-risk STS patients were randomly assigned to receive either three cycles of preoperative chemotherapy with epirubicin (120 mg/m2) and ifosfamide (9 g/m2) or the same three preoperative cycles followed by two further p…
Genome-wide analysis reveals the patterns of genetic diversity and population structure of 8 Italian local chicken breeds
2021
The aim of this study was to conduct a genome-wide comparative analysis of 8 local Italian chicken breeds (Ermellinata di Rovigo, Millefiori di Lonigo [PML], Polverara Bianca, Polverara Nera, Padovana, Pepoi [PPP], Robusta Lionata, and Robusta Maculata), all under a conservation plan, to understand their genetic diversity and population structure. A total of 152 animals were analyzed using the Affymetrix Axiom 600 K Chicken Genotyping Array. The levels of genetic diversity were highest and lowest in PML and PPP, respectively. The results of genomic inbreeding based on runs of homozygosity (ROH; FROH) showed marked differences among breeds and ranged from 0.161 (PML) to 0.478 (PPP). Furtherm…