Search results for "Reaction"

showing 10 items of 6134 documents

ChemInform Abstract: 1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD), 7-Methyl-TBD (MTBD) and the Polymer-Supported TBD (P-TBD): Three Efficient Catalysts …

2010

Abstract The 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) and its 7-methyl derivative (MTBD) have been proven to be of great synthetic utility as catalysts in the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to a variety of carbonyl compounds. The catalysts were in many cases superior to the parent tetramethylguanidine (TMG). In general the reaction proceeds in a few minutes at 0°C. The polymer-supported-TBD (P-TBD) was also proven to be an efficient promoter of the above cited nucleophilic additions.

chemistry.chemical_compoundAddition reactionNitroaldol reactionchemistryNucleophileOrganic chemistryGeneral MedicineDerivative (chemistry)Ene reactionPolymer supportedCatalysisChemInform
researchProduct

ChemInform Abstract: Highly Enantioselective Copper(I)-Catalyzed Conjugate Addition of 1,3-Diynes to α,β-Unsaturated Trifluoromethyl Ketones.

2015

The conjugate diynylation of α,β-saturated trifluoromethyl ketones is carried out at low catalytic loading (2.5 mol% for aryl substituents) of a copper(I)—MeO-BIPHEP complex, triethylamine and a terminal 1,3-diyne.

chemistry.chemical_compoundAddition reactionTrifluoromethylChemistryArylEnantioselective synthesischemistry.chemical_elementGeneral MedicineMedicinal chemistryTriethylamineCopperCatalysisConjugateChemInform
researchProduct

Synthesis and reactivity of β-amino-α,β-unsaturated oxa- and thiazolines

1992

Abstract A simple and efficient route to masked β-amino-α,β-unsaturated acids 3 by reaction of metalated oxa- and thiazolines with nitriles has been developed. The reactivity of 3 has also been explored.

chemistry.chemical_compoundAddition reactionchemistryNitrileOrganic ChemistryDrug DiscoveryOrganic chemistryReactivity (chemistry)AlkylationBiochemistryCombinatorial chemistryEnamineTetrahedron Letters
researchProduct

Addition reactions of heterocycles. VI. Reactions of 1,2-dimethylpyrrole and 1-methyl-2-carbomethoxypyrrole with nitrilimines

1978

Addition reactions of 1,2-dimethylpyrrole and 1-methyl-2-carbomethoxypyrrole with C-acetyl-N-phenylnitrilimine, have been investigated. 1,2-Dimethylpyrrole gives three different types of adducts: i.e. bis-cycloadducts (Vc) and (VIc), spirocycloadduct (IX), and non cyclic bis-adduct (XII). On the other hand, 1-methyl-2-carbomethoxypyrrole gives the bis-cycloadduct (VIb) only. Compound XII arises probably through a double 1,3-addition reaction, whereas the formation of cycloadducts Vc, VIc, and IX depends on the substituents present at C2 of the pyrrole ring and consequentially on the intermediary occurence of mono-cycloadduct (IIIc), its methylenic tautomer VII, VIc, and XL The behaviour of …

chemistry.chemical_compoundAddition reactionchemistryStereochemistryOrganic ChemistryPyrazolineRing (chemistry)Cleavage (embryo)Medicinal chemistryTautomerPyrrolidineAdductPyrroleJournal of Heterocyclic Chemistry
researchProduct

Addition reactions of heterocycles. VII. Pyrrole andC-Acetyl-N-phenylnitrilimine

1978

The addition reaction of C-acetyl-N-phenylnitrilimine to pyrrole has been investigated. The products obtained show that the reaction proceeds via two distinct pathways. The 1,3-addition reaction leads to the non-cyclic-adduct III, whereas the 1,3-cycloaddition reaction gives a mixture of regioisomeric Δ2-pyrroline IV and V, and Δ1 -pyrroline VI and VII mono-cycloadducts. These latter compounds cannot be isolated because they undergo a further 1,3-cycloaddition reaction leading to the N-substituted bis-adducts X and XI, and to the bis-adduets XII and XIII. The stereochemical assignment for X, XI, XII and XIII is provided by nmr data which suggest also that in X and XI the rotation around the…

chemistry.chemical_compoundAddition reactionchemistryStereochemistryOrganic ChemistryPyrrolineNmr dataPyrroleJournal of Heterocyclic Chemistry
researchProduct

ChemInform Abstract: Hydrophobically Directed Aldol Reactions: Polystyrene-Supported L-Proline as a Recyclable Catalyst for Direct Asymmetric Aldol R…

2008

A simple synthetic methodology for the preparation of a polystyrene-supported L-proline material is reported, and this material has been used as catalyst in direct asymmetric aldol reactions between several ketones and arylaldehydes to furnish aldol products in high yields and stereoselectivities. Screening of solvents showed that these reactions take place only in the presence of water or methanol, at lower levels of conversion in the latter case. This solvent effect, coupled with the observed high stereoselectivities, has been explained in terms of the formation of a hydrophobic core in the inner surface of the resin, whereas the hydrophilic proline moiety lies at the resin/water interfac…

chemistry.chemical_compoundAldol reactionChemistryMoietyOrganic chemistryStereoselectivityGeneral MedicineProlinePolystyreneMethanolSolvent effectsCatalysisChemInform
researchProduct

Supported Organocatalysts as a Powerful Tool in Organic Synthesis

2010

no abstract

chemistry.chemical_compoundAldol reactionchemistryOrganocatalysisOrganocatalysisAldol reactionPhase transfer catalysisOrganic chemistryOrganic synthesisα--selenenylation of aldehydesPrimary amine catalysis
researchProduct

Kinetische untersuchungen zur reaktionsfähighkeit von chlormethylgruppen in methylendiphenolen

1984

The chloromethyl derivatives of 16 differently substituted methylenediphenols were synthesized for the first time. To compare their reactivity, the solvolysis in methanol and the animolysis with an excess of p-nitroaniline in dimethyl sulfoxide were studied kinetically at 25°C. The rate constants for the methanolysis do not differ very much, beside of the fact that para-chloromethyl derivatives react about 100 times faster than ortho-chloromethyl derivatives. However, for the aminolysis a large acceleration up to 103 was found for compounds having both hydroxyl groups in ortho-position to the methylene bridge. Obviously, the cleavage of the OH bond, which occurs in the rate determining step…

chemistry.chemical_compoundAminolysisReaction rate constantchemistryHydrogen bondIntramolecular forcePolymer chemistryReactivity (chemistry)Methylene bridgeSolvolysisRate-determining stepDie Makromolekulare Chemie
researchProduct

Influence of hydrogen peroxide on the kinetics of phenol photodegradation in aqueous titanium dioxide dispersion

1990

Abstract The influence of hydrogen peroxide on the phenol photodegradation rate under near UV radiation was investigated in homogeneous and heterogeneous systems: the heterogeneous systems were aqueous dispersions of titanium dioxide (anatase). The hydrogen peroxide photodecomposition reaction was also investigated for all the systems used. The highest rate of phenol photodegradation was observed in the heterogeneous system for the contemporary presence of hydrogen peroxide and oxygen. The rate equations for phenol photodegradation and hydrogen peroxide photodecomposition for both systems were obtained. A mechanistic model able to explain the main experimental results is also proposed.

chemistry.chemical_compoundAnataseReaction rate constantchemistryTitanium dioxideInorganic chemistryGeneral EngineeringPhotocatalysisPhenolPhotochemistryPhotodegradationHydrogen peroxideCatalysisApplied Catalysis
researchProduct

1974

chemistry.chemical_compoundAnionic addition polymerizationMonomerReaction rate constantChemistryPolymer chemistryMethyl methacrylateDie Makromolekulare Chemie
researchProduct