Search results for "Replacement"

showing 10 items of 561 documents

Analysis of the Past Lifetime in a Replacement Model through Stochastic Comparisons and Differential Entropy

2020

A suitable replacement model for random lifetimes is extended to the context of past lifetimes. At a fixed time u an item is planned to be replaced by another one having the same age but a different lifetime distribution. We investigate the past lifetime of this system, given that at a larger time t the system is found to be failed. Subsequently, we perform some stochastic comparisons between the random lifetimes of the single items and the doubly truncated random variable that describes the system lifetime. Moreover, we consider the relative ratio of improvement evaluated at x &isin

General MathematicsReliability (computer networking)Context (language use)02 engineering and technologystochastic ordersLifetime distribution01 natural sciencesMeasure (mathematics)differential entropyDifferential entropy010104 statistics & probabilitystochastic neuronal modelFixed time0202 electrical engineering electronic engineering information engineeringComputer Science (miscellaneous)Applied mathematicsreliability; replacement model; stochastic orders; differential entropy; stochastic neuronal modelreplacement model0101 mathematicsEngineering (miscellaneous)Mathematicsreliabilitylcsh:Mathematicslcsh:QA1-939020201 artificial intelligence & image processingReplacement procedureRandom variableMathematics
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Editorial: Genetics and gene therapy of lysosomial storage disorders

2018

Non applicabile in quanto editoriale

Geneticsbusiness.industryAnimalGenetic enhancementGenetic TherapyLysosomeLysosomal Storage DiseasesDisease Models AnimalLysosomal Storage DiseaseDrug DiscoveryGeneticsAnimalsHumansMolecular MedicineMedicineEnzyme Replacement TherapyLysosomesbusinessMolecular BiologyGenetics (clinical)Bone Marrow TransplantationHuman
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Perceived stress in relation to quality of life and resilience in patients with advanced chronic kidney disease undergoing hemodialysis

2021

Background: Patients with chronic kidney disease undergo various stages of therapeutic adaptation which involve lifestyle modifications, physical changes, and adjustment to renal replacement therapy. This process produces adaptive stress. Objective: To identify how resilience, health- related quality of life, and sociodemographic, clinical, and hemodialysis routine-related variables are related to perceived stress in patients with chronic kidney disease receiving hemodialysis for more than six months. Methods: This was a multicenter and cross-sectional study involving 144 patients from the Valencian Community (Spain). The assessment scales used for the study were the Perceived Stress Scale …

Gerontology050103 clinical psychologyHealth Toxicology and Mutagenesismedicine.medical_treatmentmedia_common.quotation_subjectperceived stressPsychological interventionlcsh:MedicineArticle03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Renal DialysisStress (linguistics)medicineHumans0501 psychology and cognitive sciences030212 general & internal medicineRenal replacement therapyRenal Insufficiency Chronicresiliencemedia_commonbusiness.industrylcsh:R05 social sciencesPublic Health Environmental and Occupational HealthRegression analysisResilience Psychologicalmedicine.diseaseCross-Sectional Studiesquality of lifeSpainHemodialysisPsychological resiliencebusinessStress Psychologicalchronic kidney diseaseKidney disease
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Multidisciplinary management of Hunter syndrome.

2009

Hunter syndrome is a rare, X-linked disorder caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase. In the absence of sufficient enzyme activity, glycosaminoglycans accumulate in the lysosomes of many tissues and organs and contribute to the multisystem, progressive pathologies seen in Hunter syndrome. The nervous, cardiovascular, respiratory, and musculoskeletal systems can be involved in individuals with Hunter syndrome. Although the management of some clinical problems associated with the disease may seem routine, the management is typically complex and requires the physician to be aware of the special issues surrounding the patient with Hunter syndrome, and a multidiscipl…

GerontologyAdultMalemedicine.medical_specialtyAdolescentGenotypeIdursulfaseDiseaseIduronate SulfataseYoung AdultInternal medicineAnesthesiologymedicineHumansEnzyme Replacement TherapyCooperative BehaviorIntensive care medicineChildInfusions IntravenousMucopolysaccharidosis IIRandomized Controlled Trials as TopicPatient Care Teambusiness.industryHematopoietic Stem Cell TransplantationInfant NewbornInfantHunter syndromeEnzyme replacement therapymedicine.diseaseCombined Modality TherapyRecombinant ProteinsPulmonologyPhenotypeOtorhinolaryngologyChild PreschoolPediatrics Perinatology and Child HealthInterdisciplinary CommunicationNeurosurgerybusinessmedicine.drugPediatrics
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High-urgency kidney transplantation in the Eurotransplant Kidney Allocation System : success or waste of organs? The Eurotransplant 15-year all-centr…

2016

Item does not contain fulltext BACKGROUND: In the Eurotransplant Kidney Allocation System (ETKAS), transplant candidates can be considered for high-urgency (HU) status in case of life-threatening inability to undergo renal replacement therapy. Data on the outcomes of HU transplantation are sparse and the benefit is controversial. METHODS: We systematically analysed data from 898 ET HU kidney transplant recipients from 61 transplant centres between 1996 and 2010 and investigated the 5-year patient and graft outcomes and differences between relevant subgroups. RESULTS: Kidney recipients with an HU status were younger (median 43 versus 55 years) and spent less time on the waiting list compared…

Graft RejectionMalemedicine.medical_treatmentMedizin030232 urology & nephrologygraft survival030230 surgery0302 clinical medicineSurveys and QuestionnairesDIALYSISYoung adultChildKidney transplantationCANDIDATESKidneyMiddle AgedPrognosis3. Good healthEuropeMulticenter Studymedicine.anatomical_structureNephrologyChild PreschoolFemaleHemodialysisAdultReoperationmedicine.medical_specialtykidneyTissue and Organ ProcurementAdolescentWaiting ListsDonor SelectionResource AllocationYoung Adult03 medical and health sciencespatient survivalInternal medicinemedicineJournal ArticleHumansComparative StudyRenal replacement therapyDialysisAgedbusiness.industryDonor selectionInfant NewbornInfantmedicine.diseaseKidney TransplantationSurgeryTransplantationhigh-urgencyPRIORITYSURVIVAL BENEFITrenalHuman medicineRenal disorders Radboud Institute for Health Sciences [Radboudumc 11]businessWAITING TIMEtransplantationNephrology, dialysis, transplantation
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Zusammenhang zwischen postoperativer Liegedauer der Redon-Drainage und Wundheilung

1997

Es wurde bei 150 Patienten mit totalendoprothetischem Huftgelenkersatz der Einflus der postoperativen Liegedauer von Redon-Drainagen auf die Wundheilung untersucht. Eine genaue Analyse der Liegedauer der Drainagen sowie deren bakterielle Keimbesiedelung sollte unter Berucksichtigung des Wundheilungsverlaufs Aufschlus uber etwaige Zusammenhange verschaffen. Auserdem sollte uberpruft werden, inwieweit die Drainagenbakteriologie eine geeignete Methode ist, eine Aussage uber die Wundsituation zu treffen. 150 Patienten wurden in drei Kollektive eingeteilt. Zwei davon (je 50 Patienten) wurden im selben Zeitraum operiert, wobei die Patienten der einen Gruppe wegen einer Wundheilungsstorung bzw. ei…

Gynecologymedicine.medical_specialtybusiness.industryMedicineSurgerybusinessHip replacement (animal)Unfallchirurgie
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Komplikationen der Redon-drainage each hüftgelenksersatzoperationen — eine analyse der ursachen

1989

Die Redon-Drainage hat die Operationsresultate entscheidend verbessert. Jedoch sind einige Komplikationen durch das Hochvakuum-System nicht zu verhindern, sie sind vielmehr sogar dadurch bedingt. Redon-Flaschen als Einwegprodukte entsprechen haufig nicht den gestellten Anforderungen. Es handelt sich nur um ein zeitweise “geschlossenes” System mit hohem Infektionsrisiko bei Flaschenwechsel. Nach Entwicklung einer vom Legen bis zum Ziehen der Drains stets geschlossenen Drainage wurden in einer prospektiven Studie nach Huftgelenksersatzoperationen verschiedene systembedingte Faktoren analysiert. Verglichen wurden die Redon-Hochvakuum-Drainage sowie ein kontinuierlich ansteigender Unterdruck bi…

Gynecologymedicine.medical_specialtybusiness.industrymedicineSurgerybusinessHip joint replacementUnfallchirurgie
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The Symmetry and Predictive Factors in Two-Stage Bilateral Hip Replacement Procedures

2021

Background: Approximately 10–25% of total hip replacement patients undergo a bilateral procedure. The purpose of this study was to compare selected parameters associated with the first and second hip arthroplasty in patients undergoing two-stage treatment due to bilateral hip osteoarthritis and establish the predictive factors for the second procedure. Methods: This study compared the data on bilateral total hip replacement surgeries conducted in the period between 2017 and 2021 (42 patients). The following parameters from the first and second procedure were compared: the prosthetic stem, head, and insert cup size

Head sizemedicine.medical_specialtypredictive factorsPhysics and Astronomy (miscellaneous)business.industryGeneral MathematicsHip replacement (animal)SurgeryTotal hip replacement surgeryChemistry (miscellaneous)QA1-939Computer Science (miscellaneous)Hip osteoarthritisMedicinehip replacementIn patientStage (cooking)businessbilateralHospital staytwo-stageMathematicssymmetry; predictive factors; two-stage; bilateral; hip replacementsymmetryTotal hip arthroplastySymmetry
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Numerical simulation of transcatheter mitral valve replacement: The dynamic implication of LVOT obstruction in the valve-in-ring case.

2022

Transcatheter mitral valve replacement (TMVR) has been used for “off-label” treatment when annuloplasty band ring for mitral repair fails. However, the complex anatomy and function of the mitral valve may lead to fatal complications as a result of the left ventricular outflow tract (LVOT) obstruction in TMVR. We report the structural and hemodynamic response of LVOT obstruction resulting from TMVR with the Edwards SAPIEN 3 Ultra (S3) device. We modified the original Living Heart Human Model (LHHM) to account for a failed mitral valve with an annuloplasty band ring and simulated the cardiac beating condition in the setting of S3 device implantation. Findings demonstrated a high dynamic behav…

Heart Valve Prosthesis ImplantationHeart Defects CongenitalHistoryCardiac CatheterizationPolymers and PlasticsRehabilitationBiomedical EngineeringBiophysicsMitral Valve InsufficiencyFinite Element (FE) analysisIndustrial and Manufacturing EngineeringVentricular Outflow ObstructionTreatment OutcomeRisk FactorsComputational Fluid Dynamic (CFD)Living heart human modelHeart Valve ProsthesisHumansMitral ValveOrthopedics and Sports MedicineBusiness and International ManagementTranscatheter mitral valve replacementJournal of biomechanics
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Impact of Prosthesis-Patient Mismatch after Mitral Valve Replacement

2016

Background and aim of the study: The study aim was to determine the impact of prosthesis-patient mismatch (PPM) on early and late clinical outcomes, left atrial and ventricular remodeling, late tricuspid valve regurgitation and pulmonary hypertension (PH) in patients after mitral valve replacement (MVR). Methods: A total of 46 patients (mean age 66 ± 9.3 years) with mitral valve diseases and undergoing isolated MVR was enrolled in the study. The mitral valve effective orifice area (EOA) was determined using the continuity equation and indexed for the patient’s body surface area (EOAi). PPM was defined as EOAi ≤1.2 cm2/m2. PH was defined as a systolic pulmonary artery pressure (sPAP) >40 mmH…

Heart Valve Prosthesis ImplantationMaleProsthesis-Patient MismatchHypertension PulmonaryHemodynamicsMitral Valve InsufficiencySettore MED/23 - Chirurgia CardiacaMitral Valve ReplacementMiddle AgedTricuspid Valve InsufficiencyTreatment OutcomeRisk FactorsHeart Valve ProsthesisProsthesis FittingHumansSettore MED/05 - Patologia ClinicaFemaleEmergenciesHospitals TeachingProsthesis-Patient Mismatch; Mitral Valve ReplacementAgedRetrospective Studies
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