Search results for "Retargeting"
showing 10 items of 15 documents
Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging
2019
Pretargeted nuclear imaging based on the ligation between tetrazines and nano-sized targeting agents functionalized with trans-cyclooctene (TCO) has recently been shown to improve both imaging contrast and dosimetry in nuclear imaging of nanomedicines. Herein, we describe the improved radiosynthesis of a 11 C-labeled tetrazine ([ 11 C]AE-1) and its preliminary evaluation in both mice and pigs. Pretargeted imaging in mice was carried out using both a new TCO-functionalized polyglutamic acid and a previously reported TCO-functionalized bisphosphonate system as targeting agents. Unfortunately, pretargeted imaging was not successful using these targeting agents in pair with [ 11 C]AE-1. Howeve…
The impact of grain size on the efficiency of embedded SIMD image processing architectures
2004
Pixel-per-processing element (PPE) ratio-the amount of image data directly mapped to each processing element-has a significant impact on the area and energy efficiency of embedded SIMD architectures for image processing applications. This paper quantitatively evaluates the impact of PPE ratio on system performance and efficiency for focal-plane SIMD image processing architectures by comparing throughput, area efficiency, and energy efficiency for a range of common application kernels using architectural and workload simulation. While the impact of grain size is affected by the mix of executed instructions within an application program, the most efficient PPE ratio often does not occur at PE…
HPMA-Based Nanoparticles for Fast, Bioorthogonal iEDDA Ligation
2019
Contains fulltext : 216143.pdf (Publisher’s version ) (Open Access) Fast and bioorthogonally reacting nanoparticles are attractive tools for biomedical applications such as tumor pretargeting. In this study, we designed an amphiphilic block copolymer system based on HPMA using different strategies to introduce the highly reactive click units 1,2,4,5-tetrazines (Tz) either at the chain end (Tz-CTA) or statistical into the hydrophobic block. This reactive group undergoes a rapid, bioorthogonal inverse electron-demand Diels-Alder reaction (iEDDA) with trans-cyclooctenes (TCO). Subsequently, this polymer platform was used for the preparation of different Tz-covered nanoparticles, such as micell…
Browser independent content based image resizing for liquid web layouts
2010
A typical problem for webdesigners is to realize pages that can be potentially accessed from a number of display devices with different screen sizes and resolutions. Liquid layouts can help for this purpose. However, they can not typically be applied to images, which need to be rescaled or deformed. In both cases usability could be deteriorated. Content-aware image resizing techniques can help for this goal by rescaling the images to the desired width while preserving important image structures. This paper presents a content-aware resizing technique which can be seamlessly integrated into web pages without any effort from the user. The results from the system application prove its effective…
Automatic aesthetic photo composition
2013
A proper aesthetic composition of photographic content does result in an actual emotional response from the watcher. In this work we propose a fully automatic computational approach to photo composi- tion. This method takes into account well-known and widely adopted aesthetic guidelines relative to picture content as a mean for guiding an optimization framework. The resulting composition is produced as the optimal combination of cropping and retargeting. The effectiveness of the results achieved by the method are tested and evaluated with several of experiments.
Physical Metaphor for Streaming Media Retargeting
2014
We here introduce an image/video retargeting method that operates arbitrary aspect ratios resizing achieved in real-time performances. Most of the literature retargeting approaches sacrifice real-time performances in behalf of quality. On the other hand, existing fast methods provide arguable results. We can obtain a valuable trade-off between effectiveness and efficiency. The method named Spring Simulation Retargeting (SSR) is mainly based on a physical springs-based simulation. The media are assumed as flexible objects composed of particles and springs with different local stiffness properties, related to the visual importance of the content. The variation of the object size generates ela…
Monte-Carlo image retargeting
2014
In this paper an efficient method for image retargeting is proposed. It relies on a monte-carlo model that makes use of image saliency. Each random sample is extracted from deformation probability mass function defined properly, and shrinks or enlarges the image by a fixed size. The shape of the function, determining which regions of the image are affected by the deformations, depends on the image saliency. High informative regions are less likely to be chosen, while low saliency regions are more probable. Such a model does not require any optimization, since its solution is obtained by extracting repeatedly random samples, and allows real-time application even for large images. Computation…
Springs-based Simulation for Image Retargeting
2011
In this paper an efficient method for image retargeting is pro- posed. It relies onto a mechanical model based on springs network. Each pixel displacement (compression or expan- sion) is given by the network response, according to the springs stiffness. The properties of the springs are deter- mined as function of the visual relevance of the pixels. Such model does not require any optimization, since its so- lution is obtained simply from a linear system of equations, allowing real-time application even for large images. The approach is fully automatic, though can be improved by interactively providing cues such as geometric constraints and/or manual relevant object labeling. The results pr…
Real-time content-aware image resizing using reduced linear model
2010
In this paper an effective and efficient method for contentaware image resizing is proposed. It is based on the solution of a linear system where each pixel displacement (compression or expansion) is determined in dependence of the visual relevance of the pixel itself. The linear nature of the model allows real-time application of the method even for large images. This fully automatic approach can be also improved by interactively providing cues such as geometric constraints and/or manual relevant object labeling. The results have proven that the presented method achieves results comparable or superior to existent strategies, while improving efficiency.
Retargeting Framework Based on Monte-carlo Sampling
2015
Advance in image technology and proliferation of acquisition devices like smartphones, digital cameras, etc., made the display of digital images ubiquitous. Many displays exist in the market, spanning within a large variety of resolutions and shapes. Thus, displaying content optimizing the available number of pixels has become a very important issue in the multimedia community, and the image retargeting problem is being widely faced. In this work, we propose an image retargeting framework based on monte-carlo sampling. We operate the non-homogeneous resizing as the composition of several simple atomic resizing functions. The shape of such atomic operator can be chosen within a set of tested…