Search results for "Rite"
showing 10 items of 2726 documents
Arboreasides A−E, Triterpene Saponins from the Bark of Cussonia arborea
2009
Five new triterpene saponins, arboreasides A-E (1-5), and two known saponins, ciwujianoside C(3) and 23-hydroxyursolic acid 28-O-alpha-L-rhamnopyranosyl-(1--4)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranosyl ester, were isolated from the bark of Cussonia arborea. The structures were established using extensive 1D and 2D NMR spectroscopic analyses and mass spectrometry.
New Acylated Triterpene Saponins from Silene fortunei that Modulate Lymphocyte Proliferation
2002
Three new acylated triterpene saponins 1-3, with a quillaic acid as aglycon, were isolated from the roots of Silene fortunei together with a known phytoecdysteroid (20-hydroxyecdysone). The compounds were characterized mainly by a combination of 2D NMR techniques, mass spectrometry, and chemical methods. Saponins 1-3, jenisseensosides C and D (4, 5), and 6 (deacylated form of 2/3 and 4/5) were found to stimulate the proliferation of the Jurkat tumor cell lines at low concentration. At high concentration, 2/3 and 4/5 inhibited the proliferation of the cells and suggested the induction of apoptosis.
The GRIP1/14-3-3 Pathway Coordinates Cargo Trafficking and Dendrite Development
2014
SummaryRegulation of cargo transport via adaptor molecules is essential for neuronal development. However, the role of PDZ scaffolding proteins as adaptors in neuronal cargo trafficking is still poorly understood. Here, we show by genetic deletion in mice that the multi-PDZ domain scaffolding protein glutamate receptor interacting protein 1 (GRIP1) is required for dendrite development. We identify an interaction between GRIP1 and 14-3-3 proteins that is essential for the function of GRIP1 as an adaptor protein in dendritic cargo transport. Mechanistically, 14-3-3 binds to the kinesin-1 binding region in GRIP1 in a phospho-dependent manner and detaches GRIP1 from the kinesin-1 motor protein …
Isolation of the silicatein-α interactor silintaphin-2 by a novel solid-phase pull-down assay.
2011
The skeleton of siliceous sponges consists of amorphous biogenous silica (biosilica). Biosilica formation is driven enzymatically by means of silicatein(s). During this unique process of enzymatic polycondensation, skeletal elements (spicules) that enfold a central proteinaceous structure (axial filament), mainly comprising silicatein, are formed. However, only the concerted action of silicatein and other proteins can explain the genetically controlled diversity of spicular morphotypes, from simple rods with pointed ends to intricate structures with up to six rays. With the scaffold protein silintaphin-1, a first silicatein interactor that facilitates the formation of the axial filament and…
The role of the silicatein-alpha interactor silintaphin-1 in biomimetic biomineralization.
2008
Biosilicification in sponges is initiated by formation of proteinaceous filaments, predominantly consisting of silicateins. Silicateins enzymatically catalyze condensation of silica nanospheres, resulting in symmetric skeletal elements (spicules). In order to create tailored biosilica structures in biomimetic approaches it is mandatory to elucidate proteins that are fundamental for the assembly of filaments. Silintaphin-1 is a core component of modularized filaments and also part of a spicule-enfolding layer. It bears no resemblance to other proteins, except for the presence of an interaction domain that is fundamental for its function as scaffold/template. In the presence of silicatein sil…
Study of a Novel High Permeability Ferrite Sheet Intended for Near Field Communication Systems
2019
The reduction of embedded portable devices involves a magnetic field interference problem when it integrates Near Field Communication (NFC) due to the presence of conductive surfaces such as ground planes, batteries or metallic enclosures. This contribution is focused on analyzing the ability of an innovative magnetic shielding based on flexible sintered ferrite sheets (FSFS) with the aim of improving the performance of that kind of systems. Thereby, a NFC emitter antenna is characterized when it is close to a conductive surface through an electromagnetic (EM) scanner. The EM scanner composed by a matrix of near field probes that make it possible to determine the effectiveness of the FSFS. …
Rod-like ferrites obtained through thermal degradation of a molecular ferrimagnet
2010
This paper presents the characteristics of iron oxides obtained through thermal degradation of a molecular ferrimagnet, {N(n-C4H9)4[Fe II
Factores de riesgo y protección del suicidio en personas mayores: una revisión sistemática
2021
La esperanza de vida se ha incrementado notablemente, no obstante, el suicidio es la principal causa de deceso no natural en la población mayor de 70 años. El objetivo de la presente investigación es revisar sistemáticamente los factores de riesgo y protección en la conducta suicida en personas mayores. Se llevó a cabo una revisión sistemática desde el enfoque PRISMA utilizando las bases de datos: PubMed, LILACS, SciELO, Google Académico y Dialnet. Se emplearon distintos descriptores en términos DeCS y MeSH con el operador booleano “AND” y, finalmente, teniendo en cuenta los criterios de inclusión y exclusión, obtuvimos 27 artículos. Los estudios revisados muestran que entre los factores de…
A Ferrite Tubular Linear Permanent Magnet Generator (FTLPMG) analysis and design
2014
Several linear synchronous generators for the exploitation of sea wave energy have been proposed. Such machines do not require reactive power for the magnetization since they use permanent magnets for the excitation. The use of permanent magnets in a rough environment such as the marine environment may be a very weak point in the application of these kind of devices. In order to overcome this difficulty, the authors in this paper propose a linear synchronous electrical generator. Its excitation uses ferrites as suitable solutions to extract energy from sea waves. This paper describes the analysis and design of an improved axially magnetized tubular permanent-magnet machine in which several …