Search results for "Routine"
showing 10 items of 146 documents
Understanding Quantum Algorithms via Query Complexity
2017
Query complexity is a model of computation in which we have to compute a function $f(x_1, \ldots, x_N)$ of variables $x_i$ which can be accessed via queries. The complexity of an algorithm is measured by the number of queries that it makes. Query complexity is widely used for studying quantum algorithms, for two reasons. First, it includes many of the known quantum algorithms (including Grover's quantum search and a key subroutine of Shor's factoring algorithm). Second, one can prove lower bounds on the query complexity, bounding the possible quantum advantage. In the last few years, there have been major advances on several longstanding problems in the query complexity. In this talk, we su…
False-Positive LSD Drug Screening Induced by a Mucolytic Medication
1998
Since the early 1990s, the ingestion of lysergic acid diethylamide (LSD) as an inexpensive alternative to amphetamine derivatives has once again become widespread (1)(2). Consequently, screening of LSD has gained importance in clinical routine. The drug screening of a patient with a severe craniocerebral trauma showed a positive LSD screening by the homogeneous immunoassay CEDIA® DAU LSD (Boehringer Mannheim). In spite of the 3-h half-life of LSD in plasma (3), the drug screening remained positive for several days. These samples …
3D finite element analysis of tool wear in machining
2008
Abstract The paper is focused on the 3D numerical prediction of tool wear in metal cutting operations. In particular, an analytical model, able to take into account the diffusive wear mechanism, was implemented through a specific subroutine. Furthermore, an advanced approach to model heat transfer phenomena at the tool–chip interface was included in the numerical simulation. The adopted simulation strategy gave the possibility to properly evaluate the tool wear. The 3D FEM results were compared with some experimental data obtained turning AISI 1045 steel using uncoated WC tool; a good agreement was found out.
Epigenetic Biomarkers
2016
Our epigenome is characterized by its ability to dynamically respond to intra- and extracellular stimuli. These epigenetic changes are reversible and consequently are potential contributors to health and disease. Epigenetic biomarkers are emerging as tools for the screening and early detection of various diseases, for prognostic and treatment monitoring, and for predicting future risk of disease development. In clinical practice, this will contribute to the development of in vitro diagnostic and prognostic tools, which in turn may also lead to advances in personalized medicine. In this chapter we propose a definition for epigenetic biomarkers and describe different technologies used for the…
Rutines gestuals i estratègies psicològiques per la millora del rendiment dels llançaments lliures de bàsquet
2019
espanolEl objetivo de la presente revision bibliografica ha sido recoger la maxima informacion posible sobre las diferentes investigaciones que se han realizado hasta el momento con el fin de estudiar o desarrollar procedimientos previos al lanzamiento de tiros libres para poder mejorar el rendimiento de los mismos. En este caso, la investigacion se ha centrado en conocer y desengranar los detalles de las diferentes rutinas gestuales y otras estrategias psicologicas puestas a prueba por todos los autores revisados. A partir de los resultados obtenidos, se ha desarrollado una recopilacion selectiva de la informacion mas esclarecedora y se han remarcado los procedimientos considerados mas imp…
(18) F-labeled folic acid derivatives for imaging of the folate receptor via positron emission tomography.
2013
The folate receptor (FR) is already known as a proven target in diagnostics and therapy of cancer. Furthermore, the FR is involved in inflammatory and autoimmune diseases. The major advantage as a valuable target is its strongly limited expression in healthy tissues. Over the past two decades, several folic acid-based radiopharmaceuticals addressing the FR have been developed, and some of them show great potential for applications in clinical routine. However, most of these radiofolates were developed for single photon emission computed tomography imaging, and only a few can be used for positron emission tomography (PET) imaging. The development of suitable (18) F-labeled derivatives for PE…
Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory
2017
Epigenetic modifications and regulators represent potential molecular elements which control relevant physiological and pathological features, thereby contributing to the natural history of human disease. These epigenetic modulators can be employed as disease biomarkers, since they show several advantages and provide information about gene function, thus explaining differences among patient endophenotypes. In addition, epigenetic biomarkers can incorporate information regarding the effects of the environment and lifestyle on health and disease, and monitor the effect of applied therapies. Technologies used to analyze these epigenetic biomarkers are constantly improving, becoming much easier…
Potencialidades de Google Maps en la investigación social aplicada
2019
In recent years, Google has devoted resources to build a complete map of the world. They constantly scan the territory, collecting a large amount of data that provides updated and complete geographic information. This allows us to have an interoperable map that provides the end user with a search tool, not only of routes but also of shops, equipment and any type of geo-referenced information. In addition, Google Maps provides a series of Application Programming Interface (API), which provides a library of set of subroutines, functions and procedures (in object-oriented programming) that can be used by other software to automate the extraction of information of the Google platform. These fre…
SIeSTA: From Concept Board to Concept Desktop
2011
Recently published social protection and dependence reports reaffirm that the elderly, the disabled, or those in situations of dependency objectively benefit from continuing to live at home with the assistance from direct family. Currently in Spain - amongst the elderly, or people in a situation of dependency - 8 out of every 10 people stay at home. The end result is that the direct family relations have the responsibility of performing 76% of the tasks during the daily routine where aid is needed. Associations for people with disabilities, however, not only report a lack of adequate aid services, but a lack of direct-family assistance as well. It is necessary, therefore, for an "evolution"…
How bilastine is used to treat allergic rhinitis and urticaria in children
2021
Management guidelines for allergic rhinitis and urticaria recommend oral second-generation antihistamines as first-line treatment. The efficacy and safety of bilastine, the newest nonsedating second-generation antihistamine, are well established in adolescents/adults with these allergic conditions. The bilastine development program for pediatric use (2–<12 years) followed EMA-authorized processes. Pharmacokinetic/pharmacodynamic simulation and modeling and a pharmacokinetic study were conducted to identify and confirm the pediatric dose (10 mg/day). A Phase III, multicenter, double-blind, randomized, placebo-controlled, parallel-group study was performed to confirm the safety of bilasti…