Search results for "S1"

showing 10 items of 755 documents

New protein clustering of breast cancer tissue proteomics using actin content as a cellularity indicator

2008

In the present study, we report the comparative proteome profiles of proteins solubilized from 37 breast cancer surgical tissues, normalized for the actin content. Blood-derived proteins were excluded from the analysis. Among the tumor-derived protein spots, a large proportion (39%) was found present in all patients. These included several glycolytic enzymes, detox and heat shock proteins, members of annexin and S100 protein families, cathepsin D, and two “rare” proteins, DDAH2 involved in the angiogenesis control, and the oncogene PARK7. Other proteins, such as psoriasin, galectin1, cofilin, peroredoxins, SH3L1, and others, showed sporadic presence and high expression level, which suggests…

ProteomicsProteomeBlotting WesternCathepsin DBreast NeoplasmsBiologyProteomicsBiochemistryS100 proteinPeptide Mappingbreast cancer tissueAnnexinHeat shock proteinCluster AnalysisHumansElectrophoresis Gel Two-DimensionalSettore BIO/06 - Anatomia Comparata E CitologiaOncogeneReproducibility of ResultsGeneral Chemistrybreast cancer tissues; proteomicsCofilinMolecular biologyActinsSettore MED/18 - Chirurgia GeneraleSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationProteomeFemale
researchProduct

Quantization on the Virasoro group

1990

The quantization of the Virasoro group is carried out by means of a previously established group approach to quantization. We explicitly work out the two-cocycles on the Virasoro group as a preliminary step. In our scheme the carrier space for all the Virasoro representations is made out of polarized functions on the group manifold. It is proved that this space does not contain null vector states, even forc≦1, although it is not irreducible. The full reduction is achieved in a striaghtforward way by just taking a well defined invariant subspace ℋ(c, h), the orbit of the enveloping algebra through the vacuum, which is irreducible for any value ofc andh. ℋ(c, h) is a proper subspace of the sp…

Pure mathematicsGroup (mathematics)Quantization (signal processing)Invariant subspaceStatistical and Nonlinear Physics81S10ManifoldGroup representation17B68Algebra58F06Null vector81R10Algebra representation22E65Mathematical PhysicsSymplectic geometryMathematics
researchProduct

STUDY REGARDING YARN TENSION DURING KNITTING ON CIRCULAR MACHINE WITH SMALL DIAMETER

2015

If yarn tension is controlled properly during knitting, it gives an improved and uniform fabric appearance. The main objective of knitters is to feed yarn to the knitting point at a low and uniform tension. To ensure that the stress do not affect yarn properties, literature recommends that the yarn tension shall be so adjusted that it fits in the field elastic. The value of the yarn stress influences not only quality of knitted product, but also the value of the knitting machine production, by the frequency rupture of yarns. This is influenced directly by the yarn stress and yarn quality. The value of this tension is influenced by a complex of factors, such as: technological diagram of the …

PurlYarn tensionSingle jerseySockslcsh:ManufacturesRibbCellulose yarnslcsh:TS1-2301Annals of the University of Oradea: Fascicle of Textiles, Leatherwork
researchProduct

Conflicting coccolithophore and geochemical evidence for productivity levels in the Eastern Mediterranean sapropel S1

2011

Abstract The cyclic development of anoxic conditions in the eastern Mediterranean deep sea waters is one of the most fascinating research topics in paleoceanographic studies. In combination with bottom water stagnation, enhanced primary production is a common explanation for the deposition of organic-rich layers (sapropels). This is supported by extensive evidence from both geochemical and micropaleontological studies. The correspondence of recent sapropel layers with peaks of the lower photic zone coccolithophore species Florisphaera profunda has been interpreted as a proxy for the development of a deep chlorophyll maximum (DCM), due to the pycnocline/nutricline shallowing into the lower p…

Pycnocline010504 meteorology & atmospheric sciencesCoccolithophoretrace elementsNannofossil Accumulation Rates Trace Elements Sapropel S1 Deep Chlorophyll Maximum010502 geochemistry & geophysicsOceanography01 natural sciencesDeep seaCoccolithBottom waterEastern Mediterranean SeaPhotic zone14. Life underwaterNannofossil Accumulation Rates0105 earth and related environmental sciencesDeep chlorophyll maximumbiologyPaleontologySapropeldeep chlorophyll maximum15. Life on landbiology.organism_classificationsapropel S1OceanographyGeologyMarine Micropaleontology
researchProduct

AN INNOVATIVE SYSTEM FOR VINEYARD MANAGEMENT IN SICILY

2010

The aim of this study was to monitor the micro-climate of the grapevine in order to detect the adversities of the spring period (especially April and May), while reducing the operating costs of the vineyard, and increasing the overall quality of grapes. For this purpose a Wireless Sensor Network (WSN) was used. Furthermore, a comparison was performed between data measured by the wireless sensors and data provided by the fixed meteorological station of the Regione Siciliana (SIAS).

QA75business.industryVineyard Wireless sensors Environmental parameters.Vineyard Wireless sensors Environmental parametersMechanical EngineeringEnvironmental engineeringlcsh:SSettore AGR/09 - Meccanica AgrariaBioengineeringAgricultural engineeringVineyardlcsh:S1-972Industrial and Manufacturing Engineeringlcsh:AgricultureAir temperatureWirelessCrop qualityEnvironmental sciencelcsh:Agriculture (General)businessCrop managementWireless sensor network
researchProduct

The GRP94 Inhibitor PU-WS13 Decreases M2-like Macrophages in Murine TNBC Tumors: A Pharmaco-Imaging Study with 99mTc-Tilmanocept SPECT

2021

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancers and is not eligible for hormone and anti-HER2 therapies. Identifying therapeutic targets and associated biomarkers in TNBC is a clinical challenge to improve patients’ outcome and management. High infiltration of CD206+ M2-like macrophages in the tumor microenvironment (TME) indicates poor prognosis and survival in TNBC patients. As we previously showed that membrane expression of GRP94, an endoplasmic reticulum chaperone, was associated with the anti-inflammatory profile of human PBMC-derived M2 macrophages, we hypothesized that intra-tumoral CD206+ M2 macrophages expressing GRP94 may represent innovative…

QH301-705.5GRP94M2-like macrophages03 medical and health sciences0302 clinical medicineBreast cancerIn vivoSpect imagingmedicineBiology (General)Triple-negative breast cancerGRP94; M2-like macrophages; triple-negative breast cancer; PU-WS13; SPECT imaging; biomarker; CD206; Tilmanocept030304 developmental biology0303 health sciencesTumor microenvironmentSPECT imagingbusiness.industryGeneral Medicinemedicine.diseasePU-WS133. Good health030220 oncology & carcinogenesisCancer researchtriple-negative breast cancerBiomarker (medicine)biomarkerbusinessCD8HormoneCells
researchProduct

Molecular barcoding for central-eastern European Crioceris leaf-beetles (Coleoptera: Chrysomelidae)

2011

Abstract Among Crioceris leaf-beetles, the two most widespread species (Crioceris asparagi and C. duodecimpunctata) are serious invasive plant pests, while another two (C. quatuordecimpunctata and C. quinquepunctata) are rare species restricted to steppe-like habitats in Eurasia. The aim of the research was to check the genetic distinctiveness of these four species and develop barcodes for their molecular identification using the mitochondrial Cytochrome Oxidase I (COI) gene and two nuclear markers: Elongation Factor 1-α (EF1-α) and Internal Transcribed Spacer 1 (ITS1). The identification of each species was possible and reliable with the use of COI and ITS1 markers. EF1-α was omitted in an…

QH301-705.5Rare speciesspecies identificationef1-αZoologyBiologyphylogenyGeneral Biochemistry Genetics and Molecular Biologyits1taxonomyBotanypestInternal transcribed spacerBiology (General)CladeGeneral Immunology and Microbiologyconservation unitsGeneral Neurosciencefungisteppeasparagus beetlesEastern europeancoiSister groupGenetic distanceGenetic markerTaxonomy (biology)General Agricultural and Biological SciencesOpen Life Sciences
researchProduct

ROS/Gazebo-Based Simulation of Quadcopter Aircrafts

2018

The main purpose of this work is to present a tutorial description on how to design and develop an observer, which is capable of estimating the position and the orientation of a drone commanded by a controller, whose shape and structure are unknown. Starting from Newton's and Euler's laws, a mathematical model describing the dynamics of a quadcopter has first been obtained. By linearizing this model it is possible to implement a Luenberger observer and validate it with simulations in a Linux environment, thanks to the use of the Ardupilot controller and the Gazebo simulator. Finally, starting from the results obtained from the simulation, it is possible to evaluate the error made in the est…

QuadcopterObserver (quantum physics)Computer sciencebusiness.industryRenewable Energy Sustainability and the EnvironmentNonlinear controlEnergy Engineering and Power TechnologyRoboticsComputer Science Applications1707 Computer Vision and Pattern RecognitionROS/GazeboNonlinear controlquad-copterDroneIndustrial and Manufacturing EngineeringRoboticComputer Networks and CommunicationControl theoryArtificial IntelligenceTrajectoryArtificial intelligenceState observerbusinessInstrumentation
researchProduct

Accuracy of Rotational Parameters Predicted by High-Level Quantum-Chemical Calculations: Case Study of Sulfur-Containing Molecules of Astrochemical I…

2018

The accuracy of rotational parameters obtained from high-level quantum-chemical calculations is discussed for molecules containing second-row atoms. The main focus is on computed rotational constants for which two statistical analyses have been carried out. A first benchmark study concerns sulfur-bearing species and involves 15 molecules (for a total of 74 isotopologues). By comparing 15 different computational approaches, all of them based on the coupled-cluster singles and doubles approach (CCSD) augmented by a perturbative treatment of triple excitations, CCSD(T), we have analyzed the effects on computed rotational constants due to (i) extrapolation to the complete basis-set limit, (ii) …

Quantum chemicalPhysics010304 chemical physicsExtrapolationComputer Science Applications1707 Computer Vision and Pattern RecognitionSulfur containing01 natural sciencesMolecular physicsComputer Science ApplicationsCore electronStatistical analyses0103 physical sciencesMoleculeIsotopologueLimit (mathematics)Physics::Chemical PhysicsPhysical and Theoretical Chemistry010303 astronomy & astrophysicsJournal of Chemical Theory and Computation
researchProduct

Enzymatic Synthesis and Antimicrobial Activity of Oligomer Analogues of Medicinal Biopolymers from Comfrey and Other Species of the Boraginaceae Fami…

2022

This study reports the first enzymatic synthesis leading to several oligomer analogues of poly[3-(3,4-dihydroxyphenyl)glyceric acid]. This biopolymer, extracted from plants of the Boraginaceae family has shown a wide spectrum of pharmacological properties, including antimicrobial activity. Enzymatic ring opening polymerization of 2-methoxycarbonyl-3-(3,4-dibenzyloxyphenyl)oxirane (MDBPO) using lipase from Candida rugosa leads to formation of poly[2-methoxycarbonyl-3-(3,4-dibenzyloxyphenyl)oxirane] (PMDBPO), with a degree of polymerization up to 5. Catalytic debenzylation of PMDBPO using H2 on Pd/C yields poly[2-methoxycarbonyl-3-(3,4-dihydroxyphenyl)oxirane] (PMDHPO) without loss in molecul…

RS1-441Poly[3-(34-dihydroxyphenyl)glyceric acid]Pharmacy and materia medicapoly[3-(34-dihydroxyphenyl)glyceric acid]; enzymatic polymerization; lipase; antimicrobial activity; Boraginaceae familyBoraginaceae familyPharmaceutical ScienceLipaseAntimicrobial activityArticleEnzymatic polymerization
researchProduct