Search results for "S1"
showing 10 items of 755 documents
Perception of the Professional Knowledge of and Education on the Medical Technology Products among the Pharmacists in the Baltic and Nordic Countries…
2016
Article
Pathogenesis and autoimmunity initiated by a viral protein-induced apoptotic bodies
2016
Ihmisen parvovirus B19 (B19) on laajalle levinnyt, yleinen virus, joka aiheuttaa lapsissa parvorokkoa (viides tauti). Aikuisille B19 aiheuttaa erinäisiä sairauksia, muun muassa nivelkipuja ja – tulehdusta, anemiaa, sekä raskaana oleville sikiöpöhöä. Lisäksi B19 infektio saattaa johtaa autoimmuunisairauksiin, kuten punahukkaan (systemic lupus erythematosus, SLE), nivelreumaan ja sydänlihastulehdukseen. Toisaalta infektio voi olla myös täysin oireeton. Mekanismit, jotka johtavat B19 tartunnasta autoimmuunisairauteen, ovat vielä tuntemattomia. Kuitenkin tiedetään, että B19:n ei-rakenteellinen proteiini NS1 on soluille tuhoisa ja aiheuttaa niiden kuoleman (apoptoosin) muodostaen solunjäännösten…
INTEGRATED SYSTEMS IN PLANT PROTECTION MANAGEMENT: FIRE BLIGHT OF ROSACEOUS PLANTS (Erwinia amylovora (Burrill) - Winslow) IN AN APPLE ORCHARD IN SIB…
2013
Integrated protection represents a modern approach, denoting a protection strategy of agro-ecosystems; and it represents a complex system employing all appropriate methods in a manner as consistent and smooth as possible, in order to maintain the biocenotic balance of agrosystems and to keep pathogens at a level at which they do not cause economic damage (so-called level of eco-efficiency). A biocenotic approach to issues of agrosystem protection against disease attack requires an acknowledgement of all aspects regarding the evolution of pests in time and space, so as to be able to intervene at the right time with all possible means. And such protection measures are not supposed to restrain…
Radiolabeling of Nanoparticles and Polymers for PET Imaging
2014
Nanomedicine has become an emerging field in imaging and therapy of malignancies. Nanodimensional drug delivery systems have already been used in the clinic, as carriers for sensitive chemotherapeutics or highly toxic substances. In addition, those nanodimensional structures are further able to carry and deliver radionuclides. In the development process, non-invasive imaging by means of positron emission tomography (PET) represents an ideal tool for investigations of pharmacological profiles and to find the optimal nanodimensional architecture of the aimed-at drug delivery system. Furthermore, in a personalized therapy approach, molecular imaging modalities are essential for patient screeni…
STUDY CONCERNING FOREST ECOLOGIC RECONSTRUCTIUON ON DEGRADED LAND IN RANGE OCOLUL SILVIC “VALEA CIBINULUI”, SALISTE, ROMANIA
2014
The study examines the stationary conditions, determine solutions to improve degraded land, assessing the cost of ecological restoration work needed in the area of improving degraded lands at Rapa - Copăcel, estimated benefits of the project and its viability. Objectives of the paper: need to introduce in the circuit of productive forest lands within the improvement of the area "La Rapa - Copăcel" danger zone where activation of the phenomena of degradation (erosion , landslides ) predominate. Out of 102.33 ha as area for improvement, the effective area of 101.6 ha is forested, representing a difference of 0.73 ha, 1.2 m wide strip that is to be the place for hedges. Viability of the projec…
THE ATTITUDE AND MOTIVATION OF BUYERS OF TRADITIONAL/ LOCAL/ BIO PRODUCTS IN THE CONTEXT OF AGROTOURISM, IN SIBIU COUNTY, ROMANIA
2013
Based on the statistical data concerning the sheep breeding in district Sibiu and on the information obtained by making investigations markets and fairs where they sell traditional/bio products, the extent was appreciated to which this products are known and desired. The survey was conducted between May and November 2012 in four locations: “Transilvania Peasant Market (Piata Taraneasca Transilvania)”, “Traditional agro-food products Fear (Targul de Produse Agroalimentare Traditionale)” from Huet Market, “Traditional Products and Handicrafts Fear (Targul de Produse Traditionale si Mestesugaresti)” inside the Carrefour hypermarket and in “Agricultural Market” Rasinari, Sibiu county. There wer…
Glicerīna transportsistēmas un Hog1 loma raugu šūnu dzīvotspējas saglabāšanā anhidrobiozes stāvoklī
2015
Šī darba mērķis bija izpētīt glicerīna transportsistēmu un Hog1p iespējamo lomu raugu šūnu dzīvotspējas saglabāšanā anhidrobiozes stāvoklī. Lai sasniegtu šo mērķi, izmantoja raugu Saccharomyces cerevisiae BY4741 un tā izogēnos celmus, kuriem trūka viens vai vairāki gēni, kuri ir atbildīgi par glicerīna transportiera Stl1p, glicerīna eksporta kanāla Fps1p un regulatorās Hog1p MAP kināzes ekspresiju raugu šūnās. Darbam bija izvirzīti sekojošie uzdevumi: izpētīt S. cerevisiae BY4741 spējas pāriet anhidrobiozes stāvoklī; novērtēt glicerīna transportsistēmu Stl1p un Fps1p, ka arī Hog1p ietekmi uz raugu šūnu rezistenci pret dehidratāciju; izpētīt raugu spējas pārdzīvot osmotisko stresu un šīs ied…
Dynamics of hydrofracturing and permeability evolution in layered reservoirs
2015
International audience; A coupled hydro-mechanical model is presented to model fluid driven fracturing in layered porous rocks. In the model the solid elastic continuum is described by a discrete element approach coupled with a fluid continuum grid that is used to solve Darcy based pressure diffusion. The model assumes poro-elasto-plastic effects and yields real time dynamic aspects of the fracturing and effective stress evolution under the influence of excess fluid pressure gradients. We show that the formation and propagation of hydrofractures are sensitive to mechanical and tectonic conditions of the system. In cases where elevated fluid pressure is the sole driving agent in a stable tec…
Optimal Resource Allocation in Multi-Hop Networks: Contention vs. Scheduling
2014
CSMA/CA (Carrier Sense Multiple Access/Collision Avoidance) is actually the most used method in ad-hoc networks for transmitting on a contending medium, even if it shows poor performance in presence of hidden nodes. To increase performance, we propose an algorithm that combines CSMA and TDMA (Time Division Multiple Access) approaches. The adopted solution consists of grouping contending nodes in non-interfering subsets and granting a different numbers of time slots to different groups, while using the CSMA to manage medium access among nodes belonging to the same subset. An optimization procedure to assign the time slots to each subset of nodes and to find an equilibrium between contention …
Aerosolization Performance of Jet Nebulizers and Biopharmaceutical Aspects
2019
In this work, 13 jet nebulizers, some of which in different configurations, were investigated in order to identify the biopharmaceutical constraints related to the quality attributes of the medicinal products, which affect their safety, efficiency, compliance, and effectiveness. The aerosolization parameters, including the aerosol output, aerosol output rate, mass median aerodynamic diameter, and fine particle fraction, were determined according to the European Standard EN 13544-1, using sodium fluoride as a reference formulation. A comparison between the aerosol output nebulization time and the fine particle fraction displayed a correlation between the aerosol quality and the nebulization …