Search results for "SAC"
showing 10 items of 3337 documents
Pasajes de París / 1: Un espacio público
2006
Contributo allo studio morfoanatomico e micromorfologico fogliare di elementi espressivi della Flora siciliana: Periploca laevigata subsp. angustifol…
2009
El diablo en el Paraíso. Derecho, teología y literatura en el Processus Satane (s. XIV)
2017
Prefacio de Alain Boureau. Traducción de Marta Madero El Diablo entra en el Paraíso, con la intención de apropiarse de la humanidad utilizando un nuevo y formidable instrumento: el proceso. Compuesto en el siglo XIV, transmitido como obra jurídica falsamente atribuida a Bartolo da Sassoferrato, el “Proceso entre el Diablo y la Virgen María” es un proceso simulado, en forma de diálogo, entre el Diablo, Cristo y la Virgen. Considerado como obra menor y casi ignorado por la historiografía, la obra constituye en realidad un extraordinario ejemplo de sincretismo cultural: el lenguaje de la teología sirve al derecho como fuente de legitimación, y a la inversa, la construcción escatológica y la mi…
High Order Compact Finite Difference Schemes for A Nonlinear Black-Scholes Equation
2001
A nonlinear Black-Scholes equation which models transaction costs arising in the hedging of portfolios is discretized semi-implicitly using high order compact finite difference schemes. A new compact scheme, generalizing the compact schemes of Rigal [29], is derived and proved to be unconditionally stable and non-oscillatory. The numerical results are compared to standard finite difference schemes. It turns out that the compact schemes have very satisfying stability and non-oscillatory properties and are generally more efficient than the considered classical schemes.
Distributed Leadership for Interconnected Worlds
2011
The technological advancements in the second half of the previous century generated the potential for participatory decision making in organizational and governmental institutions. Moreover, the digital networking environments on the Internet that enabled this type of decision making were accompanied by the emergence and establishment of on-line communities. Under this perspective, the range of communication mediated by ubiquitous computing allows problems, ideas, and suggestions of a spec ific nature to be considered when gathered into organizational and institutional virtual spaces. Within these spaces, the voices of individual customers, workers, organizational stakeholders, and/or citiz…
Documentário ficcional e responsabilidade social: a recriação da violência de gênero na televisão
2020
espanolO tratamento da violencia de genero tem experimentado uma notavel mudanca nos meios de comunicacao espanhois nas ultimas duas decadas. Propiciada pela conscientizacao e pela publicacao de codigos eticos, essa evolucao e caracterizada por abandonar o discurso que delimitava a violencia contra as mulheres na cronica de acontecimentos para aborda-la em sua dimensao de problema social com causas estruturais. Contudo, os avancos na cobertura informativa contrastam com o surgimento de modelos de docuficcao, que combinam o depoimento das vitimas e seu contexto com reconstrucoes ficcionais. Esta pesquisa tem como objetivo indagar o tratamento que esses modelos oferecem, a partir da analise d…
Evaluation of the Fermentation Dynamics of Commercial Baker’s Yeast in Presence of Pistachio Powder to Produce Lysine-Enriched Breads
2019
The present work was carried out to evaluate the microbiological, physicochemical, and sensory characteristics of fortified pistachio breads. Pistachio powder (5% w/w) was added to flour or semolina and fermented by a commercial baker’s yeast (Saccharomyces cerevisiae). Pistachio powder did not influence the biological leavening of the doughs. The kinetics of pH and total titratable acidity (TTA) during dough fermentation showed that the leavening process occurred similarly for all trials. The concentration of yeasts increased during fermentation and reached levels of 108 CFU/g after 2 h. Pistachio powder decreased the height and softness of the final breads and increased cell density…
Novel yeast extract is superior to colloidal oatmeal in providing rapid itch relief
2020
Background Approximately, 13.5% of the population suffers from chronic itch. Many cosmetic and pharmaceutical treatments for itch are available; however, cosmetic treatments are not reliably effective and most pharmaceutical formulations carry the risk of adverse events with chronic use. Aims Previously, we have reported a novel extraction process of Saccharomyces cerevisiae, that is, Baker's yeast. The extract obtained from the novel process demonstrates superior anti-itch properties compared to other yeast extracts. In our previous study, we demonstrated that, after 30 minutes, the extract significantly reduced itch when compared to a placebo lotion (P = .002). Methods In the present stud…
Safety study of sodium pentosan polysulfate for adult patients with mucopolysaccharidosis type II
2019
Current therapies for the mucopolysaccharidoses (MPS) do not effectively address skeletal and neurological manifestations. Pentosan polysulfate (PPS) is an alternative treatment strategy that has been shown to improve bone architecture, mobility, and neuroinflammation in MPS animals. The aims of this study were to a) primarily establish the safety of weekly PPS injections in attenuated MPS II, b) assess the efficacy of treatment on MPS pathology, and c) define appropriate clinical endpoints and biomarkers for future clinical trials. Subcutaneous injections were administered to three male Japanese patients for 12 weeks. Enzyme replacement therapy was continued in two of the patients while th…
An ex-vivo model for transsynovial drug permeation of intraarticular injectables in naive and arthritic synovium
2021
Abstract Estimation of joint residence time of a drug is a key requirement for rational development of intraarticular therapeutics. There is a great need for a predictive model to reduce the high number of animal experiments in early stage development. Here, a Franz-cell based porcine ex-vivo permeation model is proposed, and transsynovial permeation of fluorescently-labeled dextrans in the range of potential drug candidates (10–150 kDa), as well as a small molecule (fluorescein sodium) and charged dextran derivates, have been determined. In addition, a lipopolysaccharide (LPS) -induced synovitis model was assessed for inflammatory biomarker levels and its effect on permeation of the solute…