Search results for "SAF"

showing 10 items of 2183 documents

Association of objective visual impairment with suicidal ideation and suicide attempts among adults aged =50 years in low/middle-income countries.

2021

BackgroundThere is currently limited literature on the association between visual impairment and suicidal thoughts and behaviours, especially among older adults from low/middle-income countries (LMICs). Thus, we aimed to investigate the associations of objectively measured distance visual impairment with suicidal ideation and suicide attempts among adults aged ≥50 years from six LMICs and to identify potential mediators.MethodsCross-sectional, community-based, nationally representative data from the WHO Study on global AGEing and adult health were analysed. Objective distance visual acuity was measured using the tumbling E logMAR chart, and vision impairment was categorised as none, mild, m…

Malemedicine.medical_specialtyvisionVisual impairmentPoison controlSuicide AttemptedSuicide preventionOccupational safety and healthSuicidal Ideation03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineRisk FactorsEpidemiologyInjury preventionmedicineHumans030212 general & internal medicineSuicidal ideationDeveloping CountriesPovertyAgedbusiness.industrypublic healthLonelinessMiddle AgedSensory SystemsOphthalmologyCross-Sectional StudiesFemalevision.epidemiologymedicine.symptombusiness030217 neurology & neurosurgeryDemography
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Physical heaviness of work and sitting at work as predictors of mortality : a 26-year follow-up of the Helsinki Birth Cohort Study

2019

ObjectivesTo examine the relationships of late-career physical heaviness of work and sitting at work with mortality. A national-level job exposure matrix was used to determine the occupation-specific level of physical heaviness and sitting.DesignProspective cohort study between years 1990 and 2015.SettingCommunity.Participants5210 men and 4725 women from the Helsinki Birth Cohort Study with an occupational code at baseline (ages 45–57 years).Primary and secondary outcome measuresTotal, cardiovascular (International Classification of Diseases 10th Revision I00–I99), cancer (C00–C97) and external (S00–Y84) mortality.ResultsThe exposures, physical heaviness and sitting had a non-linear, invers…

Malephysical activityOccupational safety and health0302 clinical medicineRisk FactorsNeoplasms1506Prospective Studies030212 general & internal medicineProspective cohort studykohorttitutkimusFinlandSitting Positionphysical heavinessGeneral MedicineMiddle Aged030210 environmental & occupational health3142 Public health care science environmental and occupational health3. Good healthQuartileWork (electrical)Cardiovascular DiseasesFemaleBirth cohort1716kuolleisuusPhysical ExertioneducationJob-exposure matrixWorkloadSittingistuminen03 medical and health sciencesSex FactorsOccupational ExposureExternal causemedicineHumansMortalitySex DistributionProportional Hazards ModelsOccupational and Environmental Medicinebusiness.industryResearchmedicine.diseaseageingtyön kuormittavuusoccupational healthbusinessFollow-Up StudiesDemography
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Drug‐refractory myasthenia gravis: Clinical characteristics, treatments, and outcome

2022

[Objective] To describe the clinical characteristics and outcomes in patients with refractory myasthenia gravis (MG) and to determine the effectiveness and side effects of the drugs used for their treatment.

Maleprogressive multifocal leukoencepdiarrheacholinergic receptorplasma exchangemiddle agedadultimmunologic factornauseaanemiahypertrichosisageddrug withdrawaldiabetes mellitusdisease severityTRIALsafetycorticosteroidhypertensionImmunologyMiastenia gravismethotrexateArticlebulbar paralysispancytopeniaMuscular DiseasescompulsionMyasthenia Gravischolinesterase inhibitorcross-sectional studyHumansImmunologic FactorshumanRITUXIMABarthralgiaNeurologíaMalalties muscularsAgedRetrospective Studiesmyasthenia gravisleukopeniaabdominal painDrug testingmajor clinical studyCross-Sectional StudiesDrug side effectscyclophosphamideobservational studyNeurology (clinical)immunoglobulinFEATURESefficacyclinical outcomeelectrophysiological procedurescomputer assisted tomographyDOUBLE-BLINDTratamiento médicorituximabOutcome Assessment Health CareImmunologiamuscle specific tyrosine kinaseRegistriestacrolimusazathioprineMedicamentoGeneral Neurosciencenephrotoxicitygeneral condition deteriorationhyperplasiatrialMiddle Agedliver toxicitydrug toxicityunclassified drugfemaleEfectes secundaris dels medicamentsSAFETYFemaledouble-blindheadacheblindnessAdultAssaigs clínics de medicamentsmalefeaturesfollow uppneumoniacyclosporinemycophenolate mofetilprotein tyrosine kinaseimmunosuppressive agentallergyalopeciaEFFICACYclinical featureosteopeniaSpainprednisonehyperglycemiaautoantibodyFollow-Up Studies
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SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

2021

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 da…

Malepulmonary embolismInternationalitySettore MED/18 - CHIRURGIA GENERALEDeep veinVascular damage Radboud Institute for Health Sciences [Radboudumc 16]infectious diseasesCardiovascularSARS‐CoV‐2surgeryCOVID-19 ; SARS-CoV-2 ; deep vein thrombosis ; pulmonary embolism ; venous thromboembolismCohort StudiesPostoperative ComplicationsAnesthesiologyMedicine and Health SciencesProspective Studies610 Medicine & healthProspective cohort studyLung11 Medical and Health SciencesConfoundingHematologyMiddle AgedThrombosis17 Psychology and Cognitive SciencesCOVID-19; deep vein thrombosis; pulmonary embolism; SARS-CoV-2; venous thromboembolismPulmonary embolismCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolism.medicine.anatomical_structureCohortCOVID-19/complicationsPostoperative Complications/etiologyOriginal ArticleFemalePatient SafetyLife Sciences & BiomedicineCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolismHumanAdultmedicine.medical_specialtyAdolescentClinical Sciencesvenous thromboembolism610 Medicine & healthGlobalSurg CollaborativeVenous Thromboembolism/etiologydeep vein thrombosisNOCOVIDSurg CollaborativeYoung AdultMedicine General & InternalAge DistributionClinical ResearchCOVID‐19General & Internal MedicinemedicineHumansSex DistributionAgedScience & Technologybusiness.industrySARS-CoV-2PreventionNeurosciencesdeep vein thrombosiCOVID-19PneumoniaOdds ratioOriginal Articlesmedicine.diseaseSurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Prospective StudieGood Health and Well BeingAnesthesiology and Pain MedicineHuman medicinePostoperative ComplicationCohort StudiebusinessVenous thromboembolism[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
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Robotic surgery can be safely performed for patients and healthcare workers during COVID‐19 pandemic

2021

OBJECTIVES: To investigate the safety of robotic surgery during COVID-19 pandemic concerning new-acquired COVID-19 infections for patients and healthcare workers. PATIENTS: We performed a retrospective single-centre cohort study of patients undergoing robotic surgery in initial period of COVID-19 pandemic. Patients and Healthcare workers COVID-19 infection status was assessed by structured telephone follow-up and/or repeated nasopharyngeal swabs. RESULTS: After 61 robotic surgeries (93,5% cancer surgery), 1 patient (1.6%) had COVID-19 infection. 60 healthcare workers cumulatively exposed to 1,187 hours of robotic surgery had no infection. One patient with postoperative proof of SARS-CoV-2 h…

Malesafetymedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Health Personnel610 MedizincoronavirusBiophysicsSARS‐CoV‐203 medical and health sciences0302 clinical medicineRobotic Surgical Procedures610 Medical sciencesHealth carePandemicmedicineHumansRobotic surgery030212 general & internal medicineElective surgeryPandemicsAgedRetrospective StudiesroboticsSARS-CoV-2business.industryCOVID-19Robotic Surgical ProceduresRetrospective cohort studyMiddle AgedinfectionComputer Science Applicationsbody regions030220 oncology & carcinogenesisEmergency medicineFemaleOriginal ArticleSurgerybusiness2019‐nCoVCohort studyThe International Journal of Medical Robotics and Computer Assisted Surgery
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Health asset profiles and health indicators among 13- and 15-year-old adolescents

2018

Objectives We examined the associations between adolescents’ health assets and various health indicators (smoking, alcohol use, sleep length, physical activity, healthy eating, oral health, self-reported health, multiple health complaints). Methods A nationally representative sample was drawn from Finnish-speaking schools, comprising 13- and 15-year-old adolescents (n = 3833). The measures taken covered the adolescents’ health assets, which were labelled Family-financial, Psychological, Family-social, Friends-social, School-social, and Human. Our analysis applied two-step cluster analysis and multilevel mixed-effects binary logistic regression. Results Six asset profiles were identified: ‘L…

Maleteini-ikäisetmedicine.medical_specialtyHealth (social science)AdolescentHealth StatusAdolescent HealthPoison controlAdolescentsDisease clusterSuicide preventionOccupational safety and health03 medical and health sciences0302 clinical medicinenuoretEnvironmental healthInjury preventionHealth indicatormedicineHumansHealth assetsadolescents030212 general & internal medicineAsset (economics)ProfilesFinlandhealth care economics and organizationshealth asset profiles030505 public healthhealth indicators4. EducationPublic healthPublic Health Environmental and Occupational HealthHealth indicatorFemaleOriginal ArticleSelf Report0305 other medical sciencePsychologyterveysindikaattoritInternational Journal of Public Health
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Changes from 1986 to 2006 in reasons for liking leisure-time physical activity among adolescents

2016

Reasons for participating in physical activity (PA) may have changed in accordance with the general modernization of society. The aim is to examine changes in self-reported reasons for liking leisure-time physical activity (LTPA) and their association with self-reported LTPA over a 20-year period. Data were collected among nationally representative samples of 13-year-olds in Finland, Norway, and Wales in 1986 and 2006 (N = 9252) as part of the WHO cross-national Health Behaviour in School-aged Children (HBSC) study. Univariate ANOVAs to establish differences according to gender, year, and country were conducted. In all countries, 13-year-olds in 2006 tended to report higher importance in te…

MaletrendsHealth Knowledge Attitudes PracticePediatricsmedicine.medical_specialtyAdolescentHealth BehaviorPsychological interventionPoison controlPhysical Therapy Sports Therapy and RehabilitationSuicide preventionOccupational safety and healthyoung people03 medical and health sciencesLeisure Activities0302 clinical medicinenuoretmotivationSurveys and QuestionnairesInjury preventionmedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineta315ExerciseFinlandAnalysis of VarianceWalesNorwaybusiness.industry030229 sport sciencesta3142AchievementSocial ParticipationSocial engagementSport psychologytrenditsport psychologyliikuntapsykologiaH1FemaleHealth educationYoung peoplebusinesshuman activitiesDemographymodernizationScandinavian Journal of Medicine and Science in Sports
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Employment Status and Personal Income Before and After Onset of a Severe Mental Disorder: A Case-Control Study.

2020

Objective: Individuals with severe mental disorders have an impaired ability to work and are likely to receive income transfer payments as their main source of income. However, the magnitude of this phenomenon remains unclear. Using longitudinal population cohort register data, the authors conducted a case-control study to examine the levels of employment and personal income before and after a first hospitalization for a serious mental disorder. Methods: All individuals (N=50,551) who had been hospitalized for schizophrenia, other nonaffective psychosis, or bipolar disorder in Finland between 1988 and 2015 were identified and matched with five randomly selected participants who were the sam…

MaletulonsiirrotBipolar DisorderACCURACYtulotasoPoison controlOccupational safety and healthtyömarkkina-asema0302 clinical medicineSocial psychiatrySUPPORT030212 general & internal medicinepsychosesFinlandmedia_commonansiotulotpsykoositMiddle Agedlabour marketPsychiatry and Mental healthSchizophreniaIncomeemployment statusFemaleINDIVIDUAL PLACEMENTsosiaalipsykiatriaearningsAdultEmploymentmedicine.medical_specialtyAdolescent515 Psychologymedia_common.quotation_subjectDIAGNOSESmacromolecular substancesILLNESS03 medical and health sciencesYoung AdultPersonal incomeTransfer paymentPEOPLEmielenterveyshäiriötInjury preventionmedicineHumansBipolar disorderPsychiatryLABORincomesbusiness.industryDISABILITYtyöllisyysmedicine.disease030227 psychiatrymental disorderssocial psychiatryPsychotic DisordersCase-Control StudiesSchizophreniabusinessPsychiatric services (Washington, D.C.)
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Environmental Correlates of Motor Competence in Children -The Skilled Kids Study

2019

Environment, physical activity (PA) and motor development are tightly interwoven during childhood. We examined the associations of environmental factors with motor competence (MC) in children. Children (N = 945, 50.1% boys, age = 3–7 years, mean = 5.4 years) from 37 childcare centres in the Southern (n = 17), Central (n = 13) and Northern Finland (n = 7) participated. The environmental factors comprised the geographical location (Southern, Central and Northern Finland) and residential density (metropolitan area, city, rural area and countryside) of the childcare centres’ based on postal codes and the national population density registry. MC was measured using the Test of Gross Motor Develop…

Maleulkoiluparticipation in sportsympäristöFITNESSHealth Toxicology and Mutagenesisresidential densityasuinympäristöPoison controllcsh:MedicineLANGUAGESuicide preventionOccupational safety and health0302 clinical medicineSurveys and QuestionnairesADOLESCENTS030212 general & internal medicinegeographical locationChildFinlandMotor skillASSOCIATIONSoutdoor timeSEDENTARY BEHAVIORmotor competenceMotor SkillsCOGNITIVE-DEVELOPMENTChild PreschoolFemalePsychologyenvironmentfyysinen aktiivisuusSportsINTERVENTIONSympäristötekijätSEASONAL-VARIATIONGross motor skilllapset (ikäryhmät)Article03 medical and health scienceschildrenInjury preventionHumansmotoriset taidotliikuntaharrastusExerciseDemographylcsh:RPublic Health Environmental and Occupational Health030229 sport sciencesPERFORMANCEMetropolitan areaPHYSICAL-ACTIVITYRural areaDemographyInternational Journal of Environmental Research and Public Health
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