Search results for "SAF"

showing 10 items of 2183 documents

Revised annual post-market environmental monitoring (PMEM) report on the cultivation of genetically modified maize MON 810 in 2013 from Monsanto Euro…

2015

Question number: EFSA-Q-2015-00432On request from: European Commission; Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel) assessed the results of the general surveillance activities contained in the revised annual post-market environmental monitoring (PMEM) report for the 2013 growing season of maize MON 810 provided by Monsanto Europe S.A. The supplied data do not indicate any unanticipated adverse effects on human and animal health or the environment arising from the cultivation of maize MON 810 cultivation in 2013. Similar methodological shortcomings to those observed in previous annual PME…

MON 810literature review[SDV]Life Sciences [q-bio]Veterinary (miscellaneous)reviewTP1-1185Plant Sciencegenetically engineered organismmaizeenvironmental impactZea maysMicrobiologyAgricultural scienceadverse effectEnvironmental monitoringTX341-641Cry1Abliterature searchestransgenic plant2. Zero hungergenetic engineeringGenetically modified maizeanimal healthNutrition. Foods and food supplyeffectChemical technologyquestionnairescreeningtransgenicsliteraturegeneral surveillancerisk assessmenthealthmethodology10079 Institute of Veterinary Pharmacology and Toxicologyfarmer questionnairestechniqueadverse effects; animal health; cultivation; effects; environmental impact; food safety; genetic engineering; genetically engineered organisms; guidelines; health; impact; literature; literature reviews; maize; methodology; monitoring; questionnaires; reviews; risk assessment; screening; techniques; transgenic plants; transgenicsfood safetymonitoringSettore AGR/11 - Entomologia Generale E ApplicataGeographycultivationimpact570 Life sciences; biologyAnimal Science and ZoologyParasitologyguidelineFood Science
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Non linear and linearized combination coefficients for modal pushover analysis

2017

Current design practice and seismic codes tend to assess seismic demand of buildings by Non linear Static Analysis (NSA), based on the evaluation of the pushover curve. Earlier non-linear static analysis procedure estimate the response peak value by evaluating the push-over curve adopting a distribution of invariant forces proportional to the fundamental vibration mode. In order to include the effect of higher modes several multimodal push-over analysis procedures were proposed in literature. In In the most famous of these, namely Modal Pushover Analysis (MPA), nodal response peak values are obtained by combination of "modal" responses by the traditional SRSS or CQC methods: the use of the …

MPASettore ICAR/09 - Tecnica Delle CostruzioniCorrelation coefficientCQCPushover analysiBuilding and ConstructionSafety Risk Reliability and QualityGeotechnical Engineering and Engineering Geology
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Accomplishing the requirements within the new decree 159/2016: Comparative study of eddy currents induced in a human phantom moving near different MR…

2019

Purpose. In order to provide adequate risk-reducing procedures for MRI personnel (radiographers, anaesthetists, physicists, nurses, technicians, cleaners, etc.), different studies have been developed in the past years. Further to those, in the present work risk assessment concerned with currents induced by non-uniform static magnetic fields in MRI operators performing different tasks in prox imity of the scanner has been investigated across a set of different 1.5 T MRI scanners. Methods. The first step has been to empirically map the magnetic field around the different scanners and to select a proper adult human body as a heterogeneous volume conductor model. Then, upon observing the way ta…

MRI Exposure Safety NIRSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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Moving inside a MRI room: A risk assessment analysis

2018

Moving across the stray magnetic field generated by a medical magnetic resonance imaging system may induce electric stimulation near or even beyond the threshold of physiological significance and adequate risk-reducing procedures for the involved personnel may be re quired. With this in mind, a set of different scanners has been analysed. Results suggest that a 1.5 T magnet may be expected in general to comply with the requirements of the currently in force European Electromagnetic Fields Directive for ensuring the health and safety of workers.

MRI Exposure Safety NIRSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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Mild cognitive impairment is associated with fall-related injury among adults aged ≥65 years in low- and middle-income countries.

2021

Abstract Objectives There is a scarcity of data on the association between mild cognitive impairment (MCI) and falls, especially from low- and middle-income countries (LMICs) where 70% of all older adults reside. Thus, we investigated the association between MCI and fall-related injury among older adults residing in six LMICs (China, Ghana, India, Mexico, Russia, South Africa). Design Cross-sectional, community-based data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Methods The definition of MCI was based on the National Institute on Ageing-Alzheimer's Association criteria, and information on past 12-month fall-related injury was also collected. Multivariable l…

Male0301 basic medicineChinaAgingIndiaPoison controlLogistic regressionGhanaBiochemistrySuicide preventionOccupational safety and healthRussiaOdds*Low-and-middle-income countriesSouth Africa03 medical and health sciencesOlder adults.0302 clinical medicineEndocrinologyRisk FactorsFall-related injuryInjury preventionmental disorders*Fall-related injuryPrevalenceGeneticsHumansMedicine*Mild cognitive impairmentCognitive DysfunctionDeveloping CountriesMexicoMolecular BiologyAged*Older adultsbusiness.industryConfoundingMild cognitive impairmentHuman factors and ergonomicsSmith L. Jacob L. Kostev K. Butler L. Barnett Y. Pfeifer B. Soysal P. Grabovac I. López-Sánchez G. F. Veronese N. et al. -Mild cognitive impairment is associated with fall-related injury among adults aged ≥65 years in low- and middle-income countries.- Experimental gerontology ss.111222 2020Cell BiologyCross-Sectional Studies030104 developmental biologyLow-and-middle-income countrieAccidental FallsFemalebusiness030217 neurology & neurosurgeryDemography
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Obesogen effects after perinatal exposure of 4,4′-sulfonyldiphenol (Bisphenol S) in C57BL/6 mice

2016

International audience; Bisphenol A were removed from consumer products and replaced by chemical substitutes such as Bisphenol S (BPS). Based on their structural similarity, BPS may be obesogen like Bisphenol A in mice. Our objective was to determine the impact of BPS on lipid homeostasis in C57B1/6 mice after perinatal and chronic exposure. Pregnant mice were exposed to BPS via the drinking water (0.2; 1.5; 50 mu g/kg bw/d). Treatment began at gestational day 0 and continued in offspring up to 23-weeks old. Then, offspring mice were fed with a standard or high fat diet. The body weight, food consumption, fat mass and energy expenditure were measured. A lipid load test was performed to chec…

Male0301 basic medicineLeptinBisphenol S[ SDV.TOX ] Life Sciences [q-bio]/ToxicologyAdipose tissue010501 environmental sciencesToxicologyurologic and male genital diseases01 natural sciencesPolyethylene GlycolsMicechemistry.chemical_compoundPregnancyInduced ObesityHyperinsulinemiapériode perinataleObesogenSulfones2. Zero hungerLeptinHigh-Fat Dietsanté humaineLipidsEnergy-Balance3. Good healthSafe AlternativesobésitéAdipose TissuePrenatal Exposure Delayed Effects[SDV.TOX]Life Sciences [q-bio]/Toxicologybisphénol sFemalehormones hormone substitutes and hormone antagonistsmedicine.medical_specialtyOffspringDiet High-Fat03 medical and health sciencesInsulin resistancePhenolsInternal medicinemedicineAnimalshoméostasie lipidiqueObesityRNA MessengerTriglycerides0105 earth and related environmental sciencesDose-Response Relationship DrugAdiponectinTriglycerideInsulin-ResistanceBody WeightOverweightmedicine.diseasebisphenol S;food contaminant;perinatal exposure;low dose;obesogenPerinatal exposureMice Inbred C57BLFood contaminant030104 developmental biologyEndocrinologycontaminant chimiqueLow doseGlucoseMetabolismGene Expression RegulationchemistryIn-VitroObesogenAnalogs
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Lipidomic profiling identifies signatures of metabolic risk

2020

Background: Metabolic syndrome (MetS), the clustering of metabolic risk factors, is associated with cardiovascular disease risk. We sought to determine if dysregulation of the lipidome may contribute to metabolic risk factors. Methods: We measured 154 circulating lipid species in 658 participants from the Framingham Heart Study (FHS) using liquid chromatography-tandem mass spectrometry and tested for associations with obesity, dysglycemia, and dyslipidemia. Independent external validation was sought in three independent cohorts. Follow-up data from the FHS were used to test for lipid metabolites associated with longitudinal changes in metabolic risk factors. Results: Thirty-nine lipids were…

Male0301 basic medicineResearch paperdhSL dihydrosphingolipidBMI body mass indexlcsh:MedicineATHEROGENIC LIPOPROTEINSBioinformaticsFHS Framingham Heart StudyPC phosphatidylcholinePESA Progression of Early Subclinical Atherosclerosis0302 clinical medicineFramingham Heart StudyRisk FactorsSAFHS San Antonio Family Heart StudyLC-MS/MS liquid chromatography-tandem mass spectrometryMedicineLongitudinal StudiesMetabolic riskPLASMA SPHINGOLIPID METABOLISMPOPULATIONlcsh:R5-920education.field_of_studySPHINGOMYELINCE cholesteryl esterDysglycemiaGeneral MedicineMiddle AgedLipidomePS phosphatidylserineCardiovascular diseaseLipidsMetabolic syndrome3. Good healthCARDIOVASCULAR-DISEASE030220 oncology & carcinogenesisHEARTMetS metabolic syndromeFemaleDisease SusceptibilityLGPL lysoglycerophospholipidSL sphingolipidlcsh:Medicine (General)LPE lysophosphatidylethanolamineAdultFDR false discovery rateTAG triacylglycerolPopulationCer ceramideCVD cardiovascular diseasePE phosphatidylethanolamineDENSITY-LIPOPROTEINRisk AssessmentGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAnimalsHumanseducationT2DM type II diabetes mellitusAgedLPC lysophosphatidylcholineSM sphingomyelinbusiness.industryCERAMIDElcsh:RHDL-C High density lipoprotein cholesterolBiomarkerLipid Metabolismmedicine.diseaseObesitySphingolipidCross-Sectional Studies030104 developmental biologyDyslipidemiaERF Erasmus Family StudyLipidomicsMetabolic syndromeINDUCED INSULIN-RESISTANCEbusinessDAG diacylglycerolBody mass indexBiomarkersDyslipidemiaMRM multiple reaction monitoringFASTING GLUCOSE
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Disadvantaged neighborhoods and the spatial overlap of substantiated and unsubstantiated child maltreatment referrals

2019

Abstract Background Considerable debate exists on whether the substantiation decision is a reliable measure for rates of maltreatment. Studies have shown that risks among children victims of maltreatment versus children investigated but unsubstantiated are similar. Objective This paper aims to respond to two research questions: (1) Do most child maltreatment referrals, substantiated and unsubstantiated, come from the same neighborhoods? (2) Do substantiated and unsubstantiated referrals share the same neighborhood risk factors? Participants and settings We used geocoded data from substantiated (n = 1799) and unsubstantiated (n = 1638) child maltreatment referrals in Valencia, Spain (2004–20…

Male050103 clinical psychologyAdolescentPoison controlVulnerable PopulationsSuicide preventionOccupational safety and healthRecurrenceResidence CharacteristicsRisk FactorsInjury preventionDevelopmental and Educational PsychologyHumans0501 psychology and cognitive sciencesChild AbuseChildReferral and ConsultationSocioeconomic statusChild Protective Services05 social sciencesHuman factors and ergonomicsBayes TheoremCensusessocial sciencesDisadvantagedPsychiatry and Mental healthSocial ClassReporting biasSpainChild PreschoolPediatrics Perinatology and Child HealthFemalePsychology050104 developmental & child psychologyDemographyChild Abuse & Neglect
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Child maltreatment and alcohol outlets in Spain: Does the country drinking culture matters?

2019

Abstract Background Alcohol outlet density has been linked to rates of substantiated maltreatment both cross-sectionally and over time. Most of these studies have been conducted in Anglo-Saxon countries, especially in the U.S., but other countries, where alcohol outlets and alcohol consumption may have different social meanings, are clearly underrepresented in the literature. Objective The aim of this study was to analyze whether alcohol outlet density is associated with neighborhood-level child maltreatment risk in a South-European city. Participants and setting A longitudinal study was conducted in the city of Valencia (Spain). As spatial units, we used 552 census block groups. Family uni…

Male050103 clinical psychologyLongitudinal studyRestaurantsAlcohol DrinkingPoison controlSuicide preventionOccupational safety and healthResidence CharacteristicsRisk FactorsEnvironmental healthInjury preventionDevelopmental and Educational PsychologyHumans0501 psychology and cognitive sciencesChild AbuseLongitudinal StudiesChildAlcoholic Beverages05 social sciencesCommerceHuman factors and ergonomicsBayes TheoremDrinking culturePsychiatry and Mental healthSpainNegative relationshipPediatrics Perinatology and Child HealthFemalePsychology050104 developmental & child psychologyChild Abuse & Neglect
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Incidence rates of narcolepsy diagnoses in Taiwan, Canada, and Europe: The use of statistical simulation to evaluate methods for the rapid assessment…

2018

Vacunación; Narcolepsia; Simulación y modelado: en Vacunació; Narcolèpsia; Simulació i modelització Vaccination; Narcolepsy; Simulation and modeling Background & objectives Vaccine safety signals require investigation, which may be done rapidly at the population level using ecological studies, before embarking on hypothesis-testing studies. Incidence rates were used to assess a signal of narcolepsy following AS03-adjuvanted monovalent pandemic H1N1 (pH1N1) influenza vaccination among children and adolescents in Sweden and Finland in 2010. We explored the utility of ecological data to assess incidence of narcolepsy following exposure to pandemic H1N1 virus or vaccination in 10 sites that use…

Male:Other subheadings::Other subheadings::/epidemiology [Other subheadings]medicine.medical_treatmentlcsh:Medicine:Other subheadings::Other subheadings::/drug therapy [Other subheadings]medicine.disease_causeGeographical locations:enfermedades del sistema nervioso::trastornos del sueño-vigilia::disomnias::trastornos intrínsecos del sueño::trastornos de somnolencia excesiva::narcolepsia [NarcolepsiaENFERMEDADES]Influenza A Virus H1N1 Subtype0302 clinical medicineRisk FactorsPandemicMedicine and Health SciencesInfluenza A virusMedicinePublic and Occupational Health030212 general & internal medicineYoung adultChildlcsh:Science:Otros calificadores::Otros calificadores::/tratamiento farmacológico [Otros calificadores]Aged 80 and overVaccinesMultidisciplinaryIncidenceSimulation and ModelingIncidence (epidemiology)Vaccination:Otros calificadores::Otros calificadores::/epidemiología [Otros calificadores]Middle AgedVaccination and ImmunizationEuropeVaccinationInfectious DiseasesNeurologyInfluenza VaccinesChild PreschoolsymbolsEngineering and TechnologyFemaleSafetyNarcolèpsia - TractamentAdjuvantResearch ArticleAdultCanadaAsiaAdolescentInfectious Disease ControlImmunologyTaiwanResearch and Analysis MethodsYoung Adult03 medical and health sciencessymbols.namesakeAdjuvants ImmunologicEnvironmental healthInfluenza HumanHumansComputer SimulationEuropean UnionPoisson regressionAgedTrastorns del sonNarcolepsySwedenModels Statisticalbusiness.industrylcsh:RInfant NewbornNarcolèpsia - EpidemiologiaInfantBiology and Life SciencesDyssomniasAge GroupsR - MedicineRelative riskSignal ProcessingPopulation Groupingslcsh:QPreventive MedicinePeople and placesSleep Disordersbusiness030217 neurology & neurosurgeryPLOS ONE
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