Search results for "SAGE"

L'oralità dell'immagine. Etnografia visiva nelle comunità rurali siciliane

2018

L’opposizione ipotizzata fra tradizioni orali e scritte, che prevale in antropologia, è ingannevole: in primis perché tende ad annullare l’orale nel contrario dello scritto, e non ne comprende il modo di funzionare specifico; in secondo luogo perché non contempla la possibilità che, tra gli estremi dell’orale puro e dello scritto puro, esistano molte situazioni intermedie. Paradossalmente oggi, nella nostra società così impregnata di immagini, l’oralità è ritornata ad assumere un ruolo centrale proprio per la produzione e la comprensione del codice visivo. Questa «oralità dell’immagine» è connaturata nei nostri comportamenti quotidiani e per questo motivo risulta difficile individuarla e an…

Analysis of the spatial distribution of free radicals in ammonium tartrate by pulse EPR techniques

2009

Using pulse electron paramagnetic resonance (EPR) on a series of l(+)-ammonium tartrate (AT) dosimeters exposed to radiations with different linear energy transfer (LET), we assessed the ability of pulse EPR spectroscopy to discriminate the quality of various radiation beams such as (60)Co gamma-ray photons, protons and thermal neutrons at various doses by analyzing the local radical distributions produced by the different beams. We performed two types of pulse EPR investigations: two-pulse electron spin echo decay obtained by varying the microwave power, and a double electron-electron resonance (DEER) study. Both methods provide information about the dipolar interactions among the free rad…

Protection Motivation Theory in Information Systems Security Research

2021

Protection motivation theory (PMT) is one of the most commonly used theories to examine information security behaviors. Our systematic review of the application of PMT in information systems (IS) security and the comparison with its application for decades in psychology identified five categories of important issues that have not yet been examined in IS security research. Discussing these issues in terms of why they are relevant and important for IS security, and to what extent IS research has not considered them, offers new research opportunities associated with the study of PMT and IS security threats. We suggest how future studies can approach each of the open issues to provide a new roa…

Minimum message length clustering: an explication and some applications to vegetation data

2001

In this paper, we examine the application of a particular approach to induction, the minimum message length principle and illustrate some of the problems that can be addressed through its use. The MML principle seeks to identify an optimal model within some specified parameterised class of models and for this paper we have chosen to concentrate on a single model class, that of mixture separation or fuzzy clustering. The first section presents, in outline, an MML methodology for fuzzy clustering. We then present some applications, including the nature of the within-cluster model, examination of the univocality of results for different groups of species and the effectiveness of presence data …

Galectin-3 Impairment of MYCN-Dependent Apoptosis-Sensitive Phenotype Is Antagonized by Nutlin-3 in Neuroblastoma Cells

2012

MYCN amplification occurs in about 20-25% of human neuroblastomas and characterizes the majority of the high-risk cases, which display less than 50% prolonged survival rate despite intense multimodal treatment. Somehow paradoxically, MYCN also sensitizes neuroblastoma cells to apoptosis, understanding the molecular mechanisms of which might be relevant for the therapy of MYCN amplified neuroblastoma. We recently reported that the apoptosis-sensitive phenotype induced by MYCN is linked to stabilization of p53 and its proapoptotic kinase HIPK2. In MYCN primed neuroblastoma cells, further activation of both HIPK2 and p53 by Nutlin-3 leads to massive apoptosis in vitro and to tumor shrinkage an…

Flavouring Extra-Virgin Olive Oil with Aromatic and Medicinal Plants Essential Oils Stabilizes Oleic Acid Composition during Photo-Oxidative Stress

2021

Essential oils (EOs) from medicinal and aromatic plants (MAPs) are well-known as natural antioxidants. Their addition to extra-virgin olive oil (EVOO) can contribute to reducing fat oxidation. The main aim of this study was to improve both food shelf-life and aromatic flavour of EVOO, adding different EOs of Sicilian accessions of common sage, oregano, rosemary and thyme. The morphological and production characteristics of 40 accessions of MAPs were preliminarily assessed. EOs from the most promising accessions of MAPs were analysed by gas-chromatography and mass spectrometry. Photo-oxidative studies of the EOs were carried out and the determination of the EVOO fatty acids obtained from 4 I…

Anaplastic lymphoma kinase expression in neuroblastomas and its relationship with genetic, prognostic, and predictive factors

2011

EGFR genomic alterations in cancer: prognostic and predictive values.

2011

The role of EGFR in cancer development and progression has been recognized for long time in a variety of human malignancies including lung, head and neck, colon, breast, ovary and glioma. Recently its role as a target of antineoplastic agents has also been identified and a variety of EGFR-targeted drugs is already being used in a clinical setting and others are at present under investigation. Many data involving EGFR protein expression are now available for the choice of anti-EGFR monoclonal antibodies in colorectal cancer and with regard to EGFR gene mutations for the choice of tyrosine kinase inhibitors in lung cancer. Other EGFR-related molecular factors, including the EGFR gene copy num…

Recent Nordic research in mathematics education illustrated by examples from NORMA17

2021

A characterization of recent Nordic research in didactics of mathematics is presented based on the 32 research reports from the Nordic and Baltic countries in the proceedings from NORMA17 (The eighth Nordic conference on didactics of mathematics). Recent Nordic research in didactics of mathematics is observed from several aspects such as choice of problem, theory, method, result, and target for the message. The analyses of the papers on different levels and from a manifold of perspectives build up an image of what Nordic research in DM (didactics of mathematics) contains and represents currently. The closeness and cooperation between researchers in the Nordic countries is characteristic as …

Logistic Growth Described by Birth-Death and Diffusion Processes

2019

We consider the logistic growth model and analyze its relevant properties, such as the limits, the monotony, the concavity, the inflection point, the maximum specific growth rate, the lag time, and the threshold crossing time problem. We also perform a comparison with other growth models, such as the Gompertz, Korf, and modified Korf models. Moreover, we focus on some stochastic counterparts of the logistic model. First, we study a time-inhomogeneous linear birth-death process whose conditional mean satisfies an equation of the same form of the logistic one. We also find a sufficient and necessary condition in order to have a logistic mean even in the presence of an absorbing endpoint. Then…