Search results for "SAP"

showing 10 items of 1142 documents

Updated insights into the mechanism of action and clinical profile of the immunoadjuvant QS-21: A review

2019

Background Vaccine adjuvants are compounds that significantly enhance/prolong the immune response to a co-administered antigen. The limitations of the use of aluminium salts that are unable to elicite cell responses against intracellular pathogens such as those causing malaria, tuberculosis, or AIDS, have driven the development of new alternative adjuvants such as QS-21, a triterpene saponin purified from Quillaja saponaria. Purpose The aim of this review is to attempt to clarify the mechanism of action of QS-21 through either receptors or signaling pathways in vitro and in vivo with special emphasis on the co-administration with other immunostimulants in new adjuvant formulations, called a…

InflammasomesT-Lymphocytesmedicine.medical_treatmentHerpes zosterPharmaceutical ScienceMonophosphoryl Lipid AAPCs antigen presenting cellsMiceCMI cell mediated immunity0302 clinical medicineDrug DiscoveryHerpes Zoster VaccineMedicineNSCLC non small cell lung carcinomaCancerImmunity CellularVaccines Synthetic0303 health sciencesImmunogenicityIl-2 interleukine 2HIV human immunodeficiency virusLipid A030220 oncology & carcinogenesisCytokinesMolecular MedicineDCs dendritic cellsNK natural killerAdjuvantTLR Toll-like receptorHerpes Zoster VaccineCD cluster of differentiationAntigen-Presenting CellsCTL cytotoxic T lymphocytesHZ herpes zosterMPL 3-deacylated monophosphoryl lipidVaccine adjuvantImmunoadjuvantArticleVZV varicella zoster virus03 medical and health sciencesImmune systemAdjuvants ImmunologicAntigenPAMPs pathogen-associated molecular patternsMalaria VaccinesPRRs pathogen recognition receptorsQS-21 Quillaja saponaria Molina-fraction 21AnimalsMHC major histocompatibility complexMtb Mycobacterium tuberculosis bacteriaSARS severe acute respiratory syndromeAntigen-presenting cellIFN-γ interferon-gamma030304 developmental biologyPharmacologybusiness.industryA-β amyloid-betaTNF-α tumor necrosis factor-alphaSaponinsQS-21MalariaQuillaja saponariaComplementary and alternative medicineTCR T-cell receptorLiposomesImmunologyKLH keyhole limpet hemocyaninbusinessdLN draining lymph nodesMAPK mitogen activated protein kinasePhytomedicine
researchProduct

MOESM5 of What are the effects of even-aged and uneven-aged forest management on boreal forest biodiversity in Fennoscandia and European Russia? A sy…

2019

Additional file 5. Data extraction spreadsheet.

InformationSystems_INFORMATIONSYSTEMSAPPLICATIONSComputingMilieux_PERSONALCOMPUTINGData_FILES
researchProduct

Vapor phase epitaxy of Hg1−xCdxI2 on sapphire

1998

Abstract We demonstrate the possibility of growing Hg 1− x Cd x I 2 layers on sapphire substrates by vapor-phase epitaxy (VPE). The successful growth has been carried out using an α-HgI 2 polycrystalline source and a CdTe buffer layer grown on sapphire by metalorganic vapor phase epitaxy (MOVPE) before the Hg 1− x Cd x I 2 VPE growth. The Hg 1− x Cd x I 2 /sapphire 20–40 μm thick layers with a uniform composition in the range of x =0.2–0.6 were grown at 220–250°C for 70–300 h. The layers were studied by scanning electron microscopy, energy disperse X-ray analysis and X-ray diffractometry. Results on the layer characterization are reported and the effect of VPE conditions on the layer proper…

Inorganic ChemistryChemistryScanning electron microscopeMaterials ChemistrySapphireAnalytical chemistryMetalorganic vapour phase epitaxyCrystalliteCondensed Matter PhysicsEpitaxyLayer (electronics)Cadmium telluride photovoltaicsSolid solutionJournal of Crystal Growth
researchProduct

Structural characterization of CdTe layers grown on (0001) sapphire by MOCVD

2004

Abstract We report on the growth of CdTe layers directly onto (0 0 0 1) sapphire substrates by MOCVD. The structure and morphology of the layers have been investigated as a function of growth temperature and II/VI precursor molar ratio by X-ray diffraction and scanning electron microscopy. The texture of the samples has revealed the existence of a temperature threshold, with higher growth temperatures resulting on completely (1 1 1) oriented layers. Some of these layers contained microtwins, as indicated by the extra peaks in the {4 2 2} Φ scans, leading to the existence of two different domains. The structural quality of each domain, as well as of the sample as a whole, has been determined…

Inorganic ChemistryFacetingDiffractionCrystallographyChemistryScanning electron microscopeMaterials ChemistrySapphireTexture (crystalline)Metalorganic vapour phase epitaxyCondensed Matter PhysicsCrystal twinningCadmium telluride photovoltaicsJournal of Crystal Growth
researchProduct

Selective area vapor-phase epitaxy and structural properties of Hg1 − xCdxTe on sapphire

1997

Selective area (SA) Hg1 − xCdxTesapphire layers have been grown using the recently developed technique of the vapor-phase epitaxy (VPE) of Hg1 − xCdxTe layers on CdTesapphire heteroepitaxial substrates (HS), which we have called “VPE on HS technique” (Sochinskii et al., J. Crystal Growth 149 (1995) 35; 161 (1996) 195). First, planar CdTe (1 1 1) 5–7 μm thick layers were grown on sapphire (0 0 0 1) wafers by metalorganic vapor-phase epitaxy (MOVPE) at 340°C for 1–2.5 h using dimethylcadmium and di-isopropyltellurium as precursors. Second, CdTe/sapphire mesas were formed using standard photolithography in the form of alternating parallel linear arrays consisting of 500 × 70 μm2 elements. Thir…

Inorganic ChemistryScanning electron microscopeChemistryMaterials ChemistryAnalytical chemistrySapphireCrystal growthMetalorganic vapour phase epitaxySubstrate (electronics)Condensed Matter PhysicsEpitaxyRutherford backscattering spectrometryCadmium telluride photovoltaicsJournal of Crystal Growth
researchProduct

Study of the chemically activated sublimation of ZnSe

1999

Abstract The reactions and processes involved in the growth of ZnSe by chemically activated sublimation in a H 2 atmosphere are studied. The rate of transport as a function of source and substrate temperatures and the difference between them are determined from close spacing vapour transport experiments. According to this process, ZnSe layers are deposited on sapphire substrates by short distance chemically assisted sublimation. The experimental results are analysed and the thermodynamic constants of the transport are determined using a theoretical model for kinetically controlled processes, assuming water to act as sublimation catalyst. A preliminary optical and structural characterisation…

Inorganic ChemistryStereochemistryChemistryMass transferKineticsMaterials ChemistrySapphireAnalytical chemistrySublimation (phase transition)Condensed Matter PhysicsShort distanceCatalysisJournal of Crystal Growth
researchProduct

Isomerisierung von 2‐Alkoxycyclopropancarbonsäuren – Eine effektive Synthese von 4‐Oxocarbonsäuren

1983

(Z/E)-2-Alkoxycyclopropansaureester 2/3 werden aus Enolethern 1 und Diazoessigester hergestellt. Durch Verseifen entstehen die (Z/E)-2-Alkoxycyclopropancarbonsauren 4/5, welche in Wasser/Methanol Stereomutation zeigen. Diese Isomerisierung wird an (E)-2-Methoxy-2-phenyl-cyclopropancarbonsaure (5a) in deuterierten Losungsmitteln untersucht und mechanistisch interpretiert. Beim Erwarmen in Wasser/Methanol offnen sich die Verbindungen 4/5 quantitativ zu den entsprechenden 4-Oxocarbonsauren 6. Isomerisation of 2-Alkoxycyclopropanecarboxylic Acids – An Effective Synthesis of 4-Oxo Carboxylic Acids (Z/E)-2-2-Alkoxycyclopropanecarboxylic esters 2/3 were prepared from enol ethers 1 and ethyl diazoa…

Inorganic Chemistrychemistry.chemical_compoundEthyl diazoacetateChemistryOrganic chemistryMethanolMedicinal chemistryEnolIsomerizationSaponificationChemische Berichte
researchProduct

Chapitre 11: Goût des ingrédients et des produits cosmétiques

2020

International audience

Interactions sensoriellesPhysiologie du goûtStimuli sapidesGoût des ingrédients[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologyproduits cosmétiquesComputingMilieux_MISCELLANEOUS
researchProduct

Chapitre 15: le goût des ingrédients et des produits cosmétiques

2017

International audience

Interactions sensoriellesPhysiologie du goûtStimuli sapidesGoût des ingrédients[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologyproduits cosmétiquesComputingMilieux_MISCELLANEOUS
researchProduct

Sitoumuksenhallinta kuluttajille suunnatussa elektronisessa palvelukaupankäynnissä : edellytyksiä ja suosituksia kauppapaikan kehittäjälle

2001

Internethallintaverkkokauppasopimusoikeusliiketoimintaluotettu kolmas osapuolikuluttajatsitoumuksetkuluttajansuoja
researchProduct