Search results for "SCRIB"

Prevalence of potentially inappropriate medications and risk of adverse clinical outcome in a cohort of hospitalized elderly patients: results from t…

2014

SummaryWhat is known and objective Inappropriate prescribing is highly prevalent for older people and has become a global healthcare concern because of its association with negative health outcomes including ADEs, hospitalization and resource utilization. Beers' criteria are widely utilized for evaluating the appropriateness of medications, and an up-to-date version has recently been published. To assess the prevalence of patients exposed to PIMs at hospital discharge according to the 2003 and 2012 versions of Beers' criteria and to evaluate the risk of adverse clinical events, re-hospitalization and all-cause mortality at 3-month follow-up. Methods This cross-sectional study was held in 66…

Polypharmacy in older people: lessons from 10 years of experience with the REPOSI register

2018

As a consequence of population aging, we have witnessed in internal medicine hospital wards a progressive shift from a population of in-patients relatively young and mainly affected by a single ailment to one of ever older and more and more complex patients with multiple chronic diseases, followed as out-patients by many different specialists with poor integration and inevitably treated with multiple medications. Polypharmacy (defined as the chronic intake of five or more drugs) is associated with increased risks of drug-drug interactions and related adverse effects, prescription and intake errors, poor compliance, re-hospitalization and mortality. With this background, the Italian Society …

Comorbidities impact and de-prescribing in elderly with HCV-related liver disease: analysis of a prospective cohort.

2021

AbstractManagement for HCV has undergone a notable change using direct-acting antiviral drugs (DAAs), which are safe and effective even in elderly. Here, we define impact of comorbidities, concomitant medication and drug–drug interactions in elder patients with HCV related disease before starting DAAs regimen. We analyzed data of 814 patients prospectively enrolled at our Unit within the web based model HCV Sicily Network. Out of 814, 590 were treated with DAAs and 414 of them were older than 65 years. We divided those 414 in two groups, one including 215 patients, aged between 65 and 74 years, and another with 199 patients, aged of 75 years and over. Charlson Comorbidity Index (CCI) was as…

Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients.

2019

Depression is often under-recognized in older patients, even if antidepressants (AD) are commonly prescribed, with a prevalence of use that increase with ageing [ 1 ]. Nevertheless, even if a diagnosis of depression is established, inappropriate treatment can occur [ 2 ]. Beers criteria are the most widely screening tools used to detect inappropriate prescription of drugs in people aged 65 years or more [ 3 ]. Since 2010, attempts to adapt the Beers' criteria have been made in Europe [ 4 , 5 ]. Tricyclic drugs are the ADs to be always avoided in the elderly, owing to their anticholinergic side effects, such as cognitive impairment, delirium, urinary retention and falls [ 3 ]. Selective sero…

Laser irradiation of ZnO:Al/Ag/ZnO:Al multilayers for electrical isolation in thin film photovoltaics

2013

Laser irradiation of ZnO:Al/Ag/ZnO:Al transparent contacts is investigated for segmentation purposes. The quality of the irradiated areas has been experimentally evaluated by separation resistance measurements, and the results are complemented with a thermal model used for numerical simulations of the laser process. The presence of the Ag interlayer plays two key effects on the laser scribing process by increasing the maximum temperature reached in the structure and accelerating the cool down process. These evidences can promote the use of ultra-thin ZnO:Al/ Ag/ZnO:Al electrode in large-area products, such as for solar modules. © 2013 Crupi et al.; licensee Springer.

Non-parametric mean curvature flow with prescribed contact angle in Riemannian products

2020

Assuming that there exists a translating soliton $u_\infty$ with speed $C$ in a domain $\Omega$ and with prescribed contact angle on $\partial\Omega$, we prove that a graphical solution to the mean curvature flow with the same prescribed contact angle converges to $u_\infty +Ct$ as $t\to\infty$. We also generalize the recent existence result of Gao, Ma, Wang and Weng to non-Euclidean settings under suitable bounds on convexity of $\Omega$ and Ricci curvature in $\Omega$.

The Riemannian manifold of all Riemannian metrics

1991

In this paper we study the geometry of (M, G) by using the ideas developed in [Michor, 1980]. With that differentiable structure on M it is possible to use variational principles and so we start in section 2 by computing geodesics as the curves in M minimizing the energy functional. From the geodesic equation, the covariant derivative of the Levi-Civita connection can be obtained, and that provides a direct method for computing the curvature of the manifold. Christoffel symbol and curvature turn out to be pointwise in M and so, although the mappings involved in the definition of the Ricci tensor and the scalar curvature have no trace, in our case we can define the concepts of ”Ricci like cu…

¿Por qué la literatura?

2021

In poetry, as well as in a good part of prose works, the rhythm of words is the music that governs reason and emotion. Literature occupies an important place in my creation. In this article I describe the different procedures in which I configure its presence in my music and the main themes in four of my works: Envoi, Como el viento, Maya and Transmutación.

Existence, regularity, and boundary behaviour of generalized surfaces of prescribed mean curvature

1974

Fl�chen Beschr�nkter Mittlerer Kr�mmung in Einer Dreidimensionalen Riemannschen Mannigfaltigkeit

1973

In recent papers HILDEBRANDT [11] and HARTH [5] proved the existence of solutions of the problem of Plateau for surfaces of bounded mean curvature with fixed and free boundaries in E3 and for minimal surfaces with free boundaries in a Riemannian manifold, respectively. Here their methods will be combined to solve the problem of Plateau for surfaces of bounded mean curvature in a Riemannian manifold. This will be done for fixed and free boundaries. Moreover, isoperimetric inequalities for the solutions will be given.