Search results for "SDG"
showing 10 items of 655 documents
Disaster Resilience and Human Settlements in the Anthropocene
2023
The chapter sets the context starting from the emerging perspectives on disaster resilience and human settlements in the larger context of the proposed new geological era of Anthropocene. It explores the impact of disasters on the human settlements, giving examples and illustrating the theoretical reference framework regarding the birth of the idea of the Anthropocene. The chapter focuses on the interdisci-plinary nature of the ‘disaster resilience and human settlements’ theme in relation to the various global development agendas, including the Expanded Brown Agenda, the Hyogo Framework of Action, the Sendai Framework for Disaster Risk Reduction, the 2030 Agenda for Sustainable Development,…
Consensus On Women'S Health Aspects Of Polycystic Ovary Syndrome (Pcos)
2012
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females with a high prevalence. The etiology of this heterogeneous condition remains obscure and its phenotype expression varies. Two, widely cited, previous ESHRE/ASRM-sponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008). The present third PCOS consensus paper summarizes current knowledge and identifies knowledge gaps regarding various women's health aspects of PCOS. Relevant topics addressed-all dealt with in a systematic fashion-include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, ethnicity, preg…
Delisting of liver transplant candidates with chronic hepatitis C after viral eradication: A European study
2016
Background & Aims: All oral direct acting antivirals (DAA) have been shown to improve the liver function of patients with decompensated cirrhosis but it is presently unknown whether this clinical improvement may lead to the delisting of some patients. The aim of this study was to assess if and which patients can be first inactivated due to clinically improvement and subsequently delisted in a real life setting. Methods: 103 consecutive listed patients without hepatocellular carcinoma were treated with different DAA combinations in 11 European centres between February 2014 and February 2015. Results: The cumulative incidence of inactivated and delisted patients by competing risk analysis…
Taking into Account Patient Preferences: A Consensus Study on the Assessment of Psychological Dimensions Within Patient Preference Studies
2021
Selena Russo,1,2,* Dario Monzani,3,4,* Cathy Anne Pinto,5 Laura Vergani,3,4 Giulia Marton,3,4 Marie Falahee,6 Gwenda Simons,6 Chiara Whichello,7 Ulrik Kihlbom,8,* Gabriella Pravettoni3,4,* 1Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 2Discipline of Paediatrics, School of Women’s and Children’s Health, The University of New South Wales, Kensington, NSW, Australia; 3Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy; 4Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy; 5Department of Pharmacoepidemiology, Merck & Co., Inc., Kenilwor…
Migration Control in the Mediterranean Grenzsaum: Reading Ratzel in the Strait of Sicily
2014
Migration controls are more and more transforming borders. In this regard, this paper is a border case study focusing on the Strait of Sicily. It analyzes the border regime between Italy and its North African neighboring countries Tunisia and Libya from the point of view of the transformations of territorial borders in space and time. It provides an inventory of border control measures and instruments, and analyzes the way they actually work. The evolution of policies and practices of migration controls results in transformations of territorial borders not only in terms of their location (inward and outward flexibilization of the border) but also in terms of their shape (from boundary lines…
Ethnographic Knowledge in Urban Planning:Bridging the Gap between the Theories of Knowledge-Based and Communicative Planning
2021
Publisher Copyright: © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. ‘Knowledge-based’ approaches have recently made a breakthrough in urban planning. How to develop balance in knowledge-based planning between abstract and scientific knowledge, on the one hand, and ‘local knowledge’ on the other hand has been long debated. To this debate, we add a form of knowledge with potential for sustainable urban planning, i.e. ethnographic knowledge that could transmit an understanding of urban dwellers’ daily practices and values to planning organisations. Theoretical literature is the foundation of our argument, which we illustrate with a case study involvin…
Citizen science for scientific literacy and the attainment of sustainable development goals in normal education
2020
Curricular integration of the formal teaching of citizen science can bring to the classroom aspects of scientific literacy that encourage the involvement of citizens. In particular, these include non-epistemic aspects related to the sociology of science (which are often not transferred to the classroom). Furthermore, this practice raises awareness among students, and encourages them to become participants in the attainment of the United Nations&rsquo
Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.
2013
T-cell protein tyrosine phosphatase (TCPTP) is a ubiquitously expressed non-receptor protein tyrosine phosphatase. It is involved in the negative regulation of many cellular signaling pathways. Thus, activation of TCPTP could have important therapeutic applications in diseases such as cancer and inflammation. We have previously shown that the α-cytoplasmic tail of integrin α1β1 directly binds and activates TCPTP. In addition, we have identified in a large-scale high-throughput screen six small molecules that activate TCPTP. These small molecule activators include mitoxantrone and spermidine. In this study, we have investigated the molecular mechanism behind agonist-induced TCPTP activation.…
Genome-wide association analysis identifies six new loci associated with forced vital capacity
2014
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and followed up the top associations in 32,917 additional individuals of European ancestry. We found six new regions associated at genome-wide significance (P <5 x 10(-8)) with FVC in or near EFEMP1, BMP6, MIR129-2-HSD17B12, PRDM11, WWOX and KCNJ2. Two loci previously associated with spirometric measures (GSTCD and PTCH1) were related to FVC. Newly implicated regions were followed up in samples from African-American, Korean, Chinese and Hispani…
The Psychological Science Accelerator’s COVID-19 rapid-response dataset
2023
Funder: Amazon Web Services (AWS) Imagine Grant