Search results for "SDG"
showing 10 items of 655 documents
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
2013
Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborat…
Microneedle-Based Delivery: An Overview of Current Applications and Trends
2020
Microneedle arrays (MNA) are considered as one of the most promising resources to achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally invasive, painless system which can bypass the stratum corneum, overcoming the potential drawbacks of subcutaneous injections and other transdermal delivery systems such as chemical enhancers, nano and microparticles, or physical treatments. As a trendy field in pharmaceutical and biomedical research, its applications are constantly evolving, even though they are based on very well-established techniques. The number of molecules administered by MNA are also increasing, with insulin and vaccines administration being the …
Global urban environmental change drives adaptation in white clover
2022
Made available in DSpace on 2022-04-28T19:52:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-18 Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied am…
The Physical Activity and Nutritional INfluences in Ageing (PANINI) Toolkit: a standardized approach towards physical activity and nutritional assess…
2022
Assessing multiple domains of health in older adults requires multidimensional and large datasets. Consensus on definitions, measurement protocols and outcome measures is a prerequisite. The Physical Activity and Nutritional INfluences In Ageing (PANINI) Toolkit aims to provide a standardized toolkit of best-practice measures for assessing health domains of older adults with an emphasis on nutrition and physical activity. The toolkit was drafted by consensus of multidisciplinary and pan-European experts on ageing to standardize research initiatives in diverse populations within the PANINI consortium. Domains within the PANINI Toolkit include socio-demographics, general health, nutrition, ph…
Biomass estimator for NIR image with a few additional spectral band images taken from light UAS
2012
A novel way to produce biomass estimation will offer possibilities for precision farming. Fertilizer prediction maps can be made based on accurate biomass estimation generated by a novel biomass estimator. By using this knowledge, a variable rate amount of fertilizers can be applied during the growing season. The innovation consists of light UAS, a high spatial resolution camera, and VTT's novel spectral camera. A few properly selected spectral wavelengths with NIR images and point clouds extracted by automatic image matching have been used in the estimation. The spectral wavelengths were chosen from green, red, and NIR channels.
Using VIS/NIR and IR spectral cameras for detecting and separating crime scene details
2012
Detecting invisible details and separating mixed evidence is critical for forensic inspection. If this can be done reliably and fast at the crime scene, irrelevant objects do not require further examination at the laboratory. This will speed up the inspection process and release resources for other critical tasks. This article reports on tests which have been carried out at the University of Jyväskylä in Finland together with the Central Finland Police Department and the National Bureau of Investigation for detecting and separating forensic details with hyperspectral technology. In the tests evidence was sought after at an assumed violent burglary scene with the use of VTT's 500-900 nm wave…
The relationship between context, structure, and processes with outcomes of 6 regional diabetes networks in Europe
2018
BackgroundWhile health service provisioning for the chronic condition Type 2 Diabetes (T2D) often involves a network of organisations and professionals, most evidence on the relationships between the structures and processes of service provisioning and the outcomes considers single organisations or solo practitioners. Extending Donabedian's Structure-Process-Outcome (SPO) model, we investigate how differences in quality of life, effective coverage of diabetes, and service satisfaction are associated with differences in the structures, processes, and context of T2D services in six regions in Finland, Germany, Greece, Netherlands, Spain, and UK.MethodsData collection consisted of: a) systemat…
Assessing travel time-based accessibility to outdoor ice skating fields for children in Helsinki during the COVID-19 pandemic
2022
This paper was written within the research project called “Equality in suburban physical activity environments, YLLI” (in Finnish: Yhdenvertainen liikunnallinen lähiö, YLLI) funded by the Suburban Programme 2020–2022 (in Finnish: Lähiöohjelma 2020–2022, decision number VN/10837/2020). Informal sport is central to Finnish children’s leisure and physical activity time. This paper aims to build a better understanding of the travel time-based accessibility to informal sports facilities, specifically to ice skating fields, for children and adolescents (aged 7–19) in the city of Helsinki. We focused on the winter of 2020–2021 because COVID-19 restrictions on indoor activities resulted in ice skat…
DESIGN E TRANSIZIONE DIGITALE : nuove sfide design-driven per l’innovazione tecno-sociale
2022
How can it be possible to work salvifically on an asphyxiated society that is beingdragged down by turbo-capitalism, the ‘soft tyranny’ of algorithms and ‘data-cracy’and marked by hegemonic and centralised socio-technical systems? Starting from the-oretical reflections and multidisciplinary contributions, this paper focuses on the strate-gic importance of techno-social innovation, critically illustrating some significant design-driven experiences that outline innovative lines of development in the field of design re-search: WASP’s experimental activity (3D printing), Manzini’s reflections on hybrid localcommunities and cities in chaotic mutation, the projects of hacktivists Persico and Ia-c…
Incompiuto, una nuova linea di partenza : progettare la differenza per un futuro sostenibile
2020
Le contemporanee costruzioni incompiute, fattispecie diffusa globalmente dell’ambiente costruito in abbandono, solo di recente sono uscite dal tabù in cui le relega l’ineludibile condizione di epifania di un fallimento. Senza entrare nel merito dei significati teoretici ad esse attribuiti (oscillanti tra i poli sovente mistificatori dell’esaltazione e della demonizzazione) e guardando alle tendenze individuabili in alcune realizzazioni degli ultimi lustri, l’articolo intende contribuire alla definizione di un approccio analitico e progettuale orientato ai multidimensionali obiettivi della sostenibilità, per rispondere in modo concreto a molteplici portatori di interesse e istanze della coll…