Search results for "SEP"

Value preserving portfolio strategies in continuous-time models

1997

We present a new approach for continuous-time portfolio strategies that relies on the principle of value preservation. This principle was developed by Hellwig (1987) for general economic decision and pricing models. The key idea is that an investor should try to consume only so much of his portfolio return that the future ability of the portfolio should be kept constant over time. This ensures that the portfolio will be a long lasting source of income. We define a continuous-time market setting to apply the idea of Hellwig to securities markets with continuous trading and examine existence (and uniqueness) of value-preserving strategies in some widely used market models. Further, we discuss…

TASISpec—A highly efficient multi-coincidence spectrometer for nuclear structure investigations of the heaviest nuclei

2010

TASISpec (TASCA in Small Image mode Spectroscopy) combines composite Ge- and Si-detectors for a new detector setup aimed towards multi-coincidence gamma -ray, X-ray, conversion electron, fission fragment, and a-particle spectroscopy of the heaviest nuclei. It exploits the TASCA separator's unique small image focal mode, i.e. the fact that evaporation residues produced in fusion-evaporation reactions can be focused into an area of less than 3 cm in diameter. This provides the possibility to pack detectors in very close geometry, resulting in an unprecedented detection efficiency of radioactive decays in prompt and delayed coincidence with implanted nuclei. Crown Copyright (C) 2010 Publis…

Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27

2006

The immune response to bacterial infections must be tightly controlled to guarantee pathogen elimination while preventing tissue damage by uncontrolled inflammation. Here, we demonstrate a key role of interleukin (IL)-27 in regulating this critical balance. IL-27 was rapidly induced during murine experimental peritonitis induced by cecal ligation and puncture (CLP). Furthermore, mice deficient for the EBI3 subunit of IL-27 were resistant to CLP-induced septic peritonitis as compared with wild-type controls, and this effect could be suppressed by injection of recombinant single-chain IL-27. EBI3−/− mice displayed significantly enhanced neutrophil migration and oxidative burst capacity during…

La centrale ENEL “Tifeo” di Augusta: ricerca e progetti per il recupero

2015

L'articolo presenta il lavoro, avviato nell'ambito del Dottorato di ricerca in Architettura/Progettazione Architettonica dell'Università di Palermo e conseguente alla stipula di una apposita convenzione con l'ENEL, finalizzato ad uno studio di fattibilità per individuare proposte qualificate e innovative per la riqualificazione e il riuso della centrale termoelettrica "Tifeo" di Augusta, ormai prossima alla dismissione. Lo studio mira ad individuare una strada concreta per la protezione di quest'opera di Giuseppe Samonà, legandola ad un possibile impatto positivo nell'ambito del difficile contesto in cui essa insiste. The recovery of the central "Tifeo" Augusta (SR), a valuable work of the …

Prepulse inhibition can predict the motivational effects of cocaine in female mice exposed to maternal separation

2020

The prepulse inhibition (PPI) of the startle response can identify the rodents that are more sensitive to the effects of cocaine. Mice with a lower PPI presented a higher vulnerability to the effects of cocaine and a higher susceptibility to developing a substance use disorder (SUD). Maternal separation with early weaning (MSEW) is a relevant animal model to induce motivational alterations throughout life. Nevertheless, only a few studies on females exist, even though they are more vulnerable to stress- and cocaine-related problems. Hence, the aim of the present study was to evaluate the ability of PPI to identify females with a greater vulnerability to the long-term consequences of early s…

Role of non-coding RNAs as biomarkers of deleterious cardiovascular effects in sepsis.

2021

The mechanisms occurring during sepsis that produce an increased risk of cardiovascular (CV) disease (CVD) are poorly understood. Even less information exists regarding CV dysfunction as a complication of sepsis, particularly for sepsis-induced cardiomyopathy. However, recent research has demonstrated that non-coding RNAs, including microRNAs, long non-coding RNAs, and circular RNAs, play a crucial role in genetic reprogramming, gene regulation, and inflammation during the development of CVD. Here we describe experimental findings showing the importance of non-coding RNAs mediating relevant mechanisms underlying CV dysfunction after sepsis, so contributing to sepsis-induced cardiomyopathy. …

Large scale preparation of human MHC class II+ integrin beta(1)+ Tregs.

2010

Abstract The human CD4 + CD25 + FoxP3 + regulatory T cell population (Tregs) contains both MHC class II + and MHC class II − cells. MHC class II + Tregs belong to the integrin α 4 β 1 + subpopulation and exclusively execute contact-dependent suppressive activity. Here we present a method optimized for isolation of these MHC class II expressing Tregs from large leukaphereses products using magnetic microbeads that achieves a reproducible purity of more than 90% and enables the use of this small-sized Treg population in pre-clinical application and basic research.

Nonlinear relaxation in quantum and mesoscopic systems

2013

The nonlinear relaxation of three mesoscopic and quantum systems are investigated. Specifically we study the nonlinear relaxation in: (i) a long Josephson junction (LJJ) driven by a non-Gaussian Lévy noise current; (ii) a metastable quantum open system driven by an external periodical driving; and (iii) the electron spin relaxation process in n-type GaAs crystals driven by a fluctuating electric field. In the first system the LJJ phase evolution is described by the perturbed sine-Gordon equation. Two well known noise induced effects are found: the noise enhanced stability and resonant activation phenomena. We investigate the mean escape time as a function of the bias current frequency, nois…

Il culto di San Giuseppe

2008

L'interés de la Renaixença valenciana pels poetes de l'Edat Moderna

2013

L’Estudio histórico-crítico de los poetas valencianos de los siglos XVI, XVII i XVIII, que en 1883 publicaren Josep Maria Puig i Torralva i Francesc Martí i Grajales, representa, a hores d’ara, el major exponent de l’interés que els escriptors valencians de la segona meitat del segle XIX manifestaren pels poetes valencians de l’Edat Moderna. És a dir, pels seus predecessors. D’aquesta manera, el present treball aporta informació biogràfica i bibliogràfica sobre tots dos autors, i analitza el contingut d’una obra que, malgrat haver passat pràcticament inadvertida per als estudiosos de la literatura contemporània, ha coadjuvat a la recuperació dels escriptors valencians de l’Edat Moderna que …