Search results for "SGP"
showing 4 items of 14 documents
Performance of a RED system with ammonium hydrogen carbonate solutions
2016
The use of closed-loop salinity gradient power (SGP) technologies has been recently presented as a viable option to generate power using low-grade heat, by coupling a SGP unit with a thermally-driven regeneration process in a closed loop where artificial solutions can be adopted for the conversion of heat into power. Among these, the closed-loop reverse electrodialysis (RED) process presents a number of advantages such as the direct production of electricity, the extreme flexibility in operating conditions and the recently demonstrated large potentials for industrial scale-up. Ammonium hydrogen carbonate (NH4HCO3) is a salt suitable for such closed-loop RED process thanks to its particular …
Reverse electrodialysis with NH4HCO3-water systems for heat-to-power conversion
2017
Abstract A Reverse ElectroDialysis Heat Engine (REDHE) system operating with “thermolytic” ammonium hydrogen-carbonate (NH4HCO3) aqueous solutions as working fluids is studied. The engine is constituted by (i) a RED unit to produce electric power by mixing the solutions at different salinity and (ii) a thermally-driven regeneration unit including a stripping and an absorption column to restore the initial salinity gradient thus closing the cycle. In the present work only the RED unit and the stripping column are taken into account. In particular, a simplified integrated process model for the whole cycle was developed: it consists of (i) a lumped parameter model for the RED unit validated wi…
Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer
2021
Given the lack of effective treatments for Hepatocellular carcinoma (HCC), the development of novel therapeutic approaches is very urgent. Here, siRNAs were delivered to HCC cells by a synthetic polymer containing α,β-poly-(N-2-hydroxyethyl)-D,L-aspartamide-(PHEA) derivatized with diethylene triamine (DETA) and bearing in the side chain galactose (GAL) linked via a polyethylene glycol (PEG) to obtain (PHEA-DETA-PEG-GAL, PDPG). The GAL residue allows the targeting to the asialo-glycoprotein receptor (ASGPR), overexpressed in HCC cells compared to normal hepatocytes. Uptake studies performed using a model siRNA or a siRNA targeted against the enhanced green fluorescence protein, demonstrated …
NH4HCO3–water solutions regeneration in RED closed loop applications
2017
Reverse Electrodialysis (RED) in closed loop arrangement (Reverse Electrodialysis Heat Engine - REDHE) is a promising technology to convert low-grade waste heat into electricity. RED is a membrane process exploiting the salinity gradient between a concentrated and a diluted solution to generate electrical current. Due to the transfer phenomena occurring in the RED unit, the two exiting solutions are partially mixed. Thermal regeneration processes can be used to restore the initial conditions of the two solutions, thus closing the loop. In this regard, ammonium hydrogen carbonate (NH4HCO3) salt solutions are suitable for such applications, being able to decompose at temperatures above 40-45 …