Search results for "SIM"
showing 10 items of 10139 documents
Ordinare il tempo. Sui principi organizzativi dei calendari cerimoniali
2016
Le rappresentazioni del tempo e dello spazio variamente declinate nella storia dall’homo religiosus, in quanto riduzioni e tra- duzioni culturali dell’unicum continuum spazio- temporale in esperienze umanamente concepibili, si riflettono e si esibiscono con particolare evidenza – oltre che nelle credenze, nei miti, nell’organizzazione dei sistemi sociali, ecc. – nelle attività rituali che sostanziano le feste religiose. Questo può osservarsi tanto a livello della loro distribuzione calendariale quanto a livello della strutturazione degli specifici itinera festivi e dei relativi contenuti simbolici. Le feste, infatti, agite in tempi e spazi definiti, da un lato disgiungono, perimetrando e co…
FPGA implementation of a deep learning algorithm for real-time signal reconstruction in particle detectors under high pile-up conditions
2019
The analog signals generated in the read-out electronics of particle detectors are shaped prior to the digitization in order to improve the signal to noise ratio (SNR). The real amplitude of the analog signal is then obtained using digital filters, which provides information about the energy deposited in the detector. The classical digital filters have a good performance in ideal situations with Gaussian electronic noise and no pulse shape distortion. However, high-energy particle colliders, such as the Large Hadron Collider (LHC) at CERN, can produce multiple simultaneous events, which produce signal pileup. The performance of classical digital filters deteriorates in these conditions sinc…
Pasajes de París / 7: Su universo simbólico
2006
Optimization of the characteristic angles of both front and rear McPherson suspensions on a circular track using multi-body numerical simulation
2009
The research reported in this paper aims to simulate the road-holding of a virtual vehicle using multi-body simulation to estimate both the contact forces between the tyre and ground and the roll motion when cornering. Furthermore, the effect of the characteristic angles on the variation in the forces of the tyre in contact with the ground is studied to determine optimal values for these angles. Emphasis is placed on an average-class vehicle, of which both the external dimensions and mass are chosen appropriately, with a McPherson suspension mounted on both the front and the rear. The characteristic values of the camber and toe-in angles, in both the front and the rear, are optimized for m…
Desmantling patriarchy: political practices and Spanish feminist movement slogans in the democratic transition
2010
espanolEl movimiento feminista en Espana adquirio su mayor desarrollo en los anos setenta con el inicio de la transicion democratica. El proceso transicional representaba una oportunidad para la reivindicacion de los derechos de las mujeres y poner las nuevas bases sobre el lugar que debian ocupar en la futura sociedad democratica, asi como para denunciar la represion que la dictadura impuso al colectivo femenino. Las campanas y practicas politicas desarrolladas por el movimiento feminista en Espana fueron acompanadas de simbolos y lemas que formaban parte de la produccion simbolica del movimiento feminista como movimiento social. Estas representaciones simbolicas ayudaron configurar una id…
Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking
2015
Apigenin is a common dietary flavonoid with considerable cytotoxic activity in vitro and in vivo. Despite many mechanistic studies, less is known about resistance factors hampering apigenin's activity. We investigated the ATP-binding cassette (ABC) transporters BCRP/ABCG2, P-glycoprotein/ABCB1 and its close relative ABCB5. Multidrug-resistant cells overexpressing these ABC transporters were not cross-resistant toward apigenin. Moreover, apigenin inhibited not only P-glycoprotein but also BCRP by increasing cellular uptake of doxorubicin and synergistic inhibition of cell viability in combination with doxorubicin or docetaxel in multidrug-resistant cells. To perform in silico molecular docki…
A dosimetric study of Leipzig applicators.
2005
Purpose: To obtain the absolute dose-rate distribution in liquid water for all six cup-shaped Leipzig applicators by means of an experimentally validated Monte Carlo (MC) code. These six applicators were used in high-dose-rate (HDR) afterloaders with the “classic” and v2 192Ir sources. The applicators have an inner diameter of 1, 2, and 3 cm, with the source traveling parallel or perpendicular to the contact surface. Methods and materials: The MC GEANT4 code was used to obtain the dose-rate distribution in liquid water for the six applicators and the two HDR source models. To normalize the applicator output factors, a MC simulation for the “classic” and v2 sources in air was performed to es…
No association between human herpesvirus type 8 infection and multiple myeloma.
1998
Influence of Mitoxantrone on the Syntheses of Dna and Proteins of Mouse Tissues
1991
In view of the structural similarity of mitoxantrone to anthracyclines and its ability to intercalate into DNA, we studied its influence on the synthetic processes of DNA and proteins in CD-1 mice tissues. By studying at the DNA level the impairment of 2H-thymidine incorporation and its return to normal, it was found that bone marrow and spleen showed similar behavior, i.e., a rapid return to normal, which occurred before bone marrow cell number and spleen weight returned to basal values. At the cardiac level, the incorporation values of precursors into DNA, reduced by treatment with mitoxantrone, came back very slowly to the control ones. Hepatic DNA showed a lower sensitivity to mitoxant…