Search results for "SINGLE"
showing 10 items of 4920 documents
Replication of the association between CHRNA4 rs1044396 and harm avoidance in a large population-based sample.
2015
Harm avoidance is a personality trait characterized by excessive worrying and fear of uncertainty, which has repeatedly been related to anxiety disorders. Converging lines of research in rodents and humans point towards an involvement of the nicotinic cholinergic system in the modulation of anxiety. Most notably, the rs1044396 polymorphism in the CHRNA4 gene, which codes for the α4 subunit of the nicotinic acetylcholine receptor, has been linked to negative emotionality traits including harm avoidance in a recent study. Against this background, we investigated the association between harm avoidance and the rs1044396 polymorphism using data from N=1673 healthy subjects, which were collected …
Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible suscep…
2014
Item does not contain fulltext Bladder exstrophy-epispadias complex (BEEC), the severe end of the urorectal malformation spectrum, has a profound impact on continence as well as sexual and renal functions. It is widely accepted that for the majority of cases the genetic basis appears to be multifactorial. Here, we report the first study which utilizes genome-wide association methods to analyze a cohort comprising patients presenting the most common BEEC form, classic bladder exstrophy (CBE), to identify common variation associated with risk for isolated CBE. We employed discovery and follow-up samples comprising 218 cases/865 controls and 78 trios in total, all of European descent. Our disc…
Mobility of plume-derived volcanogenic elements in meteoric water at Nyiragongo volcano (Congo) inferred from the chemical composition of single rain…
2017
The chemical composition of single rainfall events was investigated at Nyiragongo volcano (Democratic Republic of Congo) with the aim of determining the relative contributions of plume-derived elements. The different locations of the sampling sites allowed both plume-affected samples (hereafter referred to as “fumigated samples”) and samples representative of the local background to be collected. The chemical composition of the local background reflects the peculiar geographic features of the area, being influenced by biomass burning, geogenic dust, and biological activity. Conversely, fumigated samples contain large amounts of volcanogenic elements that can be clearly distinguished from th…
Glioma Grading: The Role of Combined Perfusion MR Imaging and Single-Voxel MR Spectroscopy Compared to Conventional MR Imaging
2011
Abstract Body: Purpose To assess the contribution of combined perfusion MR imaging (MRI) and single-voxel MR spectroscopy (MRS) in grading primary gliomas compared with conventional MRI. Materials & Methods Thirty-two patients with primary cerebral glioma underwent conventional MRI, dynamic contrast-enhanced T2*-weighted perfusion MRI and single-voxel proton MRS. Gliomas were graded as low or high based on conventional MRI. The rCBV measurements were obtained from regions of maximum perfusion normalized between tumor and healthy tissue. Metabolite ratios ( [Cho]/[Cr], [Cho]/[NAA], [NAA]/[Cr]) were measured with TE: 34 ms. Tumor grade determined with the three methods then was compared with …
Iodine(I) and Silver(I) Complexes of Benzoimidazole and Pyridylcarbazole Derivatives
2021
The synthesis of iodine(I) complexes with either benzoimidazole or carbazole-derived sp 2 N -containing Lewis bases is described, as well as their corresponding silver(I) complexes. The addition of elemental iodine to the linear two-coordinate Ag(I) complexes produces iodine(I) complexes with a three-center four-electron (3c-4e) [N — I — N] + bond. The 1 H and 1 H- 15 N HMBC NMR studies unambiguously confirm the formation of the complexes in all cases via the [N — Ag — N] + → [N — I — N] + cation exchange, with the 15 N NMR chemical shift change between 94 to 111 ppm when compared to the free ligand. The single crystal X-ray crystallographic studies on four I + complexes revealed highly sym…
Very strong −N–X+⋯−O–N+ halogen bonds
2016
A new (-)N-X(+)(-)O-N(+) paradigm for halogen bonding is established by using an oxygen atom as an unusual halogen bond acceptor. The strategy yielded extremely strong halogen bonded complexes with very high association constants characterized in either CDCl3 or acetone-d6 solution by (1)H NMR titrations and in the solid-state by single crystal X-ray analysis. The obtained halogen bond interactions, RXB, in the solid-state are found to be in the order of strong hydrogen bonds, viz. RXB ≈ RHB.
"Table 3" of "Cross section and longitudinal single-spin asymmetry $A_L$ for forward $W^{\pm}\rightarrow\mu^{\pm}\nu$ production in polarized $p$$+$$…
2023
Single-spin asymmetries at forward $A^{FW}_L$ and backward $A^{BW}_L$ rapidities for $p$+$p$ collisions at $\sqrt{s}$ = 510 GeV for results in 2013 and 2012, plus combined results for both years.
"Conclusion" of "Cross section and longitudinal single-spin asymmetry $A_L$ for forward $W^{\pm}\rightarrow\mu^{\pm}\nu$ production in polarized $p$$…
2023
The total $W$ boson production cross sections for $p$+$p$ collisions at $\sqrt{s}$ = 510 GeV for $\sigma$($W^+$ $\rightarrow$ $\mu^+$) and $\sigma$($W^-$ $\rightarrow$ $\mu^-$).
Browsing hinders the regeneration of broadleaved trees in uneven-aged forest management in southern Finland
2020
Uneven-aged forest management has attained increasing popularity. It may benefit biodiversity, buffer against pests and abiotic damages, decrease runoff from clearcuts and improve recreational values. We studied how gap cuttings and single-tree selection cuttings influence browsing damage in spruce-dominated forests in south-central Finland. Overall, browsing damage was especially frequent in aspen and rowan, but also in birch. The larger the basal area left in harvesting, the lower the browsing pressure on birch and rowan; neither the harvesting method nor the seedling density had an independent effect on browsing damage. Although larger tree retention levels may reduce browsing damage, th…
Algorithmic issues in computational intelligence optimization: from design to implementation, from implementation to design
2016
The vertiginous technological growth of the last decades has generated a variety of powerful and complex systems. By embedding within modern hardware devices sophisticated software, they allow the solution of complicated tasks. As side effect, the availability of these heterogeneous technologies results into new difficult optimization problems to be faced by researchers in the field. In order to overcome the most common algorithmic issues, occurring in such a variety of possible scenarios, this research has gone through cherry-picked case-studies. A first research study moved from implementation to design considerations. Implementation limitations, such as memory constraints and real-time r…