Search results for "SIP"
showing 10 items of 1280 documents
Effect of Glutathione on Canine Myocardial Ischaemia Without Reperfusion
1993
Abstract The present study was to evaluate the effect of exogenous glutathione on myocardial damage resulting from permanent (no reperfusion) coronary ligation (3 or 6 h) in anaesthetized dogs. Haemodynamics, infarct size and myocardial glutathione content were determined. Erythrocyte superoxide dismutase (SOD) activity was also determined in coronary venous blood samples. Glutathione was administered by the intraperitoneal route, 100 mg kg−1 as initial dose given 5 min before coronary ligation, and successive doses of 25 mg kg−1 every 40 min throughout the study period. Saline-treated dogs showed myocardial infarction, a decrease in myocardial glutathione content, and a transient increase …
Influence of therapeutic and toxic doses of neuroleptics and antidepressants on energy metabolism of the isolated perfused rat brain.
1973
The isolated perfused rat brain was used for a comparative study of the effects of promazine, imipramine, monodesmethyl promazine and desipramine on cerebral energy metabolism. After perfusion for 30 min or 1 h the brain levels of the following substrates and metabolites were estimated: P-creatine, creatine, ATP, ADP, AMP, glycogen, glucose, glucose-6-P, fructose diphosphate, dihydroxyacetone-P, pyruvate, lactate, α-ketoglutarate, and ammonia. Drug concentrations of 5·10−6 M and 10−5 M in the perfusion medium caused a significant decrease of glucose-6-P alone. When the drug concentration was raised to a toxic range (10−4 M), reflected in the EEG by the pattern of secondary discharges, an ac…
Evaluation of immunologic effect of Enniatin A and quantitative determination in feces, urine and serum on treated Wistar rats.
2014
Abstract Study of dietary supplementation with ENN A mycotoxin during 28 days of exposure time on Wistar rats to determinate its levels in serum, urine and feces and, to evaluate the immunologic effect in peripheral blood lymphocytes (PBL) is presented. The first method for ENN A extraction, determination and detection by LC–MS/MS in serum, urine and feces samples is reported. ENN A food dose administrated was detected in serum samples and influenced lymphocyte phenotyping. Levels in serum were founded from the second week of the experiment; reaching values of 4.76 μg/ml on the fourth week, which corresponds to 3.24 μg/ml in blood. PBL as T helper (CD4 + ) were presented in greater percenta…
Uptake of [3H]dopamine into dopaminergic and noradrenergic neurones of the isolated neurointermediate lobe of the rat hypophysis. Effects of desipram…
1983
The isolated neurointermediate lobe (NIL) of the rat hypophysis accumulates [3H]dopamine from the incubation medium. Column chromatographic analysis showed that 92% of the tissue radioactivity was contained in the catecholamine fraction. [3H]Dopamine represented 70% and [3H]noradrenaline 30% of the [3H]catecholamines. Desipramine (1 microM) prevented the formation of [3H]noradrenaline without affecting the storage of [3H]dopamine. Nomifensine (10 microM) blocked the storage of [3H]dopamine and [3H]noradrenaline. Thus, in the NIL, [3H]dopamine is taken up into dopaminergic and noradrenergic neurones. In the latter, [3H]dopamine is converted to [3H]noradrenaline, indicating a significant dopa…
Analytical Study of the Thermal Induced Oscillations Known as Heartbeats
1998
Abstract A laser beam traveling horizontally at a short distance below the free surface of an absorbing solution exhibits various oscillatory states (periodic, quasiperiodic, and chaotic) which depend on both the buoyancy (Archimedes force) and the thermal coefficient of the surface tension (Marangoni effect). The beam oscillations have been called “heartbeats.” In this work, the heartbeats were produced by pumping 1-(2-pyridylazo)-2-naphthol (PAN) solutions in silicone oil with an Ar+continuous-wave laser beam. The relationships between PAN concentration and the other parameters that control the oscillatory behavior were studied. The frequency of the oscillations sensitively varied with sm…
Special Issue on Higher education and its clients : institutional responses to changes in demand and in environment
2002
02048
Statistical analysis of β decays and the effective value of gA in the proton-neutron quasiparticle random-phase approximation framework
2016
We perform a Markov chain Monte Carlo (MCMC) statistical analysis of a number of measured groundstate-to-ground-state single β+/electron-capture and β− decays in the nuclear mass range of A = 62–142. The corresponding experimental comparative half-lives (log f t values) are compared with the theoretical ones obtained by the use of the proton-neutron quasiparticle random-phase approximation (pnQRPA) with G-matrixbased effective interactions. The MCMC analysis is performed separately for 47 isobaric triplets and 28 more extended isobaric chains of nuclei to extract values and uncertainties for the effective axial-vector coupling constant gA in nuclear-structure calculations performed in the p…
Gas-liquid mass transfer rates in unbaffled tanks stirred by PBT: scale-up effects and pumping direction
2018
Abstract Unbaffled stirred tanks are increasingly recognized as a viable alternative to common baffled tanks for a range of applications such as biochemical, food or pharmaceutical processes where the presence of baffles is undesirable for some reason. In this work, the mass transfer performance of unbaffled stirred tanks with pitched blade turbine, operating either in up-pumping or down-pumping mode, was investigated. The influence of impeller size and liquid viscosity were also investigated. The mass transfer intensity was measured by means of the Simplified Dynamic Pressure. Method The measurements concerned both coalescent and non-coalescent (viscous) batches. Results confirm that incre…
Damping of rotor conical whirl by asymmetric dry friction suspension
2009
Abstract A new technique for the rotor whirl damping in rotating machinery, based on the elastic suspension of the journal boxes and the use of dry friction surfaces normal to the shaft axis between their supports and the frame, is here analysed theoretically for several cases of rotor systems characterized by mass and constraint asymmetry, where gyroscopic effects are to be expected and conical whirl motions may grow up. The critical flexural speeds can be easily cut off by an adhesive state of the supports and the whirl amplitude can be minimized as well throughout the remaining sliding range. Confining the operative angular speed of the rotor in the range of adhesive contact between the …
Relaxor ferroelectric PbSc1/2Nb1/2O3—PbZn1/3Nb2/3O3— PbMg1/3Nb2/3O3ceramics
2000
Abstract Original ternary solid solutions PbSc1/2Nb1/2O3 — PbZn1/3Nb2/3O3-PbMg1/3Nb2/3O3 (PSN-PZN-PMN) have been synthesized by solid state reaction from oxides. Ceramic samples have been obtained by both conventional and hot pressing techniques. The density of the obtained hot pressed ceramics reaches 98% of the value calculated from X-ray data. Dense, high quality samples of pure PZN and compositions containing over 0.8 molar parts of PZN could not be obtained — porosity was up to 10% and they were mainly comprised of the cubic pyrochlore phase. Density, porosity, water absorbtivity, and dielectric permittivity and dissipation factor of the ceramic samples have been measured. Data of diff…