Search results for "SLI"

Adaptive meshes in computer graphics and model-based simulation

2006

Monet luonnonlait voidaan ilmaista matemaattisesti joko yhtenä yhtälönä tai yhtälöjärjestelmänä. Erityisesti differentiaaliyhtälöiden ratkaisu on tärkeä esimerkiksi mekaniikassa, biologiassa tai kemiassa esiin tuleva ongelma. Useimmissa tapauksissa ratkaisu tällaisiin yhtälöihin on tuntematon, joten se täytyy löytää käyttäen tietokonekoodia. Koska tietokoneet toimivat rajoitetulla tarkkuudella ja tietomäärällä, tietokoneella saatu ratkaisu on vain approksimaatio yhtälön ratkaisulle. Tämän epätarkan tiedon käyttö tietokoneavusteisessa tekniikassa voi johtaa laitteen toimintahäiriöihin. Onkin tärkeää saada kuva, kuinka hyvin tietokoneella saatu tulos edustaa tarkkaa ratkaisua. Turchyn kehitti…

Puheista teoiksi : toimintatutkimus konsultoivan erityisliikunnanopettajan viran perustamisesta

2007

Unrooting inequality from development : recognition and justification of inequality in global development

2017

How does the tension resolve between a moral order with egalitarian imperatives, such as sustainable and inclusive human development, and a global political economy based on a market system that prioritizes meeting the wants and needs of those with purchasing power? By developing a comprehensive theoretical framework as analytical contribution, I propose to rethink a practice-intensive field (Development and International Cooperation) and analyze the texts that represent the dominant discourse in development policies: the UNDP Human Development Reports and the World Bank’s World Development Reports. These influential institutions have shaped the rise of neoliberalism as a hegemonic developm…

Textbooks as ‘Neoliberal artifacts’: a critical study of knowledge-making in ELT industry

2022

The present study examined the traces of neoliberal ideology in O-level English language textbooks taught in elitist private schools in Pakistan that follow the UK-based international educational system administrated by the University of Cambridge under the General Certificate of Education (GCE). Analysis in the study was informed by Fairclough's CDA writings. Moreover, Bourdieu's views on neoliberalism were also considered to shed some light on neoliberal ideology in the textbooks. Findings suggest that several neoliberal themes were evident in the textbooks under scrutiny, including marketization, consumerism, branding, celebrity culture, competition, individualism, self-responsibility an…

Implicit regulation for automotive variators

2001

A well-known practice uses mechanical variators to realize the so-called continuously variable transmissions (CVTs) for automotive application. A remarkable problem for one of the most used CVTs is given by the hydraulic control of the axial thrust on the half-pulleys that is necessary for torque transmission. It involves a heavy decrease in transmission efficiency. In the present paper, the possible production of the required axial thrust by a simple spring to eliminate hydraulic losses is analysed. It is shown that the power capacity of such a regulated variator is near to the maximum possible, and the belt torque loss is always considerably lower than the sum of the belt and pump losses…

Obstructive sleep apnea is an independent predictor for dyslipidemia: Data from the European Sleep Apnea Database (ESADA)

2017

Background and aim: Obstructive sleep apnea (OSA) and dyslipidemia are both independently well-recognized risk factors for cardiovascular disease. Previous data are inconclusive regarding the relationship between OSA and dyslipidemia. The aim of the present study was to investigate the association between OSA and dyslipidemia in ESADA (European Sleep Apnea Database). Methods: The cross-sectional analysis included 8592 patients (age 50.1±12.7 years, 69.1% male, BMI 30.8±6.6 kg/m2, mean AHI 25.7±25.9 n/h) from the ESADA. The independent relationship between measures of OSA (AHI, ODI, mean and lowest saturation) and lipid profile (total cholesterol [TC], HDL-cholesterol [HDL-C] (n=3289) and fa…

Multigenerational study of the obesogen effects of bisphenol S after a perinatal exposure in C57BL6/J mice fed a high fat diet.

2021

International audience; Background : Bisphenol S is an endocrine disruptor exhibiting metabolic disturbances, especially following perinatal exposures. To date, no data are available on the obesogen effects of BPS in a mutligenerational issue.Objectives : We investigated obesogen effects of BPS in a multigenerational study by focusing on body weight, adipose tissue and plasma parameters in male and female mice.Methods : Pregnant C57BL6/J mice were exposed to BPS (1.5 μg/kg bw/day ie a human equivalent dose of 0.12 μg/kg bw/day) by drinking water from gestational day 0 to post natal day 21. All offsprings were fed with a high fat diet during 15 weeks. Body weight was monitored weekly and fat…

Cardiovascular risk in psoriatic arthritis, a narrative review

2020

Abstract Introduction Psoriatic arthritis (PsA) is a chronic inflammatory rheumatism characterized for a long time by a high degree of cardiovascular risk. Chronic inflammation is one of the mechanisms that explain this cardiovascular excess of risk through direct and indirect pathways. In recent years, epidemiological data have changed somewhat since the increasing use of bio-drugs that are effective in reducing this inflammation. The purpose of this review is to assess the current state of cardiovascular morbidity and mortality in PsA and thus to assess the cardiovascular risk in case of PsA. Method We conducted a literature review using Pubmed and Medline databases with the following key…

The effects of ezetimibe on LDL-cholesterol: quantitative or qualitative changes ?

2009

Ezetimibe represents the first of a new class of agents, the cholesterol absorption inhibitors, able to reduce low-density lipoproteins (LDL)-cholesterol by 15-25% from baseline in monotherapy and on top of statins and fibrates. To-date all the data regarding the efficacy of ezetimibe comes from the studies of its lipid-lowering power. Yet, recent findings from the ENHANCE study on atherosclerosis progression showed that the addition of ezetimibe to simvastatin in patients with heterozygous familial hypercholesterolemia did not affect the mean change in carotid intima-media thickness, although a significant reduction in LDL-cholesterol levels was present. Therefore, we cannot exclude that e…

Atherogenic dyslipidemia and oxidative stress: a new look

2009

Although results from in vitro studies and clinical trials demonstrate strong associations between oxidative stress and cardiovascular risk, to date still no convincing data are available to suggest that treatment with antioxidants might reduce vascular events. Oxidative modifications of low-density lipoproteins (LDL) represent an early stage of atherosclerosis, and small, dense LDL are more susceptible to oxidation than larger, more buoyant particles. Oxidized LDL are independent predictors of subclinical and clinical atherosclerosis. Recent studies suggested that novel therapeutic strategies may take into account the removal of such particles from circulation. Future research is required …