Search results for "SPD"
showing 10 items of 22 documents
Prehistoric palaeodemographics and regional land cover change in eastern Iberia
2019
Much attention has been placed on the drivers of vegetation change on the Iberian Peninsula. While climate plays a key role in determining the species pools within different regions and exerts a strong influence on broad vegetation patterning, the role of humans, particularly during prehistory, is less clear. The aim of this paper is to assess the influence of prehistoric population change on shaping vegetation patterns in eastern Iberia and the Balearic Islands between the start of the Neolithic and the late Bronze Age. In all, 3385 radiocarbon dates have been compiled across the study area to provide a palaeodemographic proxy (radiocarbon summed probability distributions (SPDs)). Modelled…
Incorporating Biotic Information in Species Distribution Models: A Coregionalized Approach
2021
In this work, we discuss the use of a methodological approach for modelling spatial relationships among species by means of a Bayesian spatial coregionalized model. Inference and prediction is performed using the integrated nested Laplace approximation methodology to reduce the computational burden. We illustrate the performance of the coregionalized model in species interaction scenarios using both simulated and real data. The simulation demonstrates the better predictive performance of the coregionalized model with respect to the univariate models. The case study focus on the spatial distribution of a prey species, the European anchovy (Engraulis encrasicolus), and one of its predator spe…
Dealing with physical barriers in bottlenose dolphin (Tursiops truncatus) distribution
2019
Abstract Worldwide, cetacean species have started to be protected, but they are still very vulnerable to accidental damage from an expanding range of human activities at sea. To properly manage these potential threats we need a detailed understanding of the seasonal distributions of these highly mobile populations. To achieve this goal, a growing effort has been underway to develop species distribution models (SDMs) that correctly describe and predict preferred species areas. However, accuracy is not always easy to achieve when physical barriers, such as islands, are present. Indeed, SDMs assume, if only implicitly, that the spatial effect is stationary, and that correlation is only depende…
Applicability of hybrid linear ion trap-high resolution mass spectrometry and quadrupole-linear ion trap-mass spectrometry for mycotoxin analysis in …
2012
Abstract Recent developments in mass spectrometers have created a paradoxical situation; different mass spectrometers are available, each of them with their specific strengths and drawbacks. Hybrid instruments try to unify several advantages in one instrument. In this study two of wide-used hybrid instruments were compared: hybrid quadrupole-linear ion trap-mass spectrometry (QTRAP ® ) and the hybrid linear ion trap-high resolution mass spectrometry (LTQ-Orbitrap ® ). Both instruments were applied to detect the presence of 18 selected mycotoxins in baby food. Analytical parameters were validated according to 2002/657/CE. Limits of quantification (LOQs) obtained by QTRAP ® instrument ranged …
Daylighting offices: A first step toward an analysis of photobiological effects for design practice purposes
2014
Abstract The research presented in this paper reports an analysis of daylight in three offices with different exposures and characteristics located in Naples (Italy). The goal was to fully investigate daylight characteristics, also considering the circadian impact of daylight entering these offices, with the hope to develop guidelines to better assess daylight quality in built environments. One of the main findings of this research is that the spectral distributions and CCTs of the light reaching the eye of a person seated at the desk in these offices are similar irrespective of the offices' different characteristics (dimensions, surfaces' spectral reflectances, external obstructions, etc.)…
Hsp60 Inhibitors and Modulators
2019
In this chapter, we focus on the 60 KDa Heat Shock Protein (Hsp60) and discuss some of its biological, molecular and pathological features. The structural and mechanistic aspect of the Hsp60 folding cycle will be also presented. We further illustrate how Hsp60 may be involved in many diseases and therefore considered as an effective therapeutic or theranostic target. Finally, the state-of-the-art on the development of Hsp60 and bacterial GroEL inhibitors and modulators of their expression will be illustrated. This is discussed in the light of a negative chaperonotherapy, and the consequent development of inhibitors, as well as positive chaperonotherapy, in the event its excessive activity i…
Single molecule localization microscopy of the distribution of chromatin using Hoechst and DAPI fluorescent probes.
2014
Several approaches have been described to fluorescently label and image DNA and chromatin in situ on the single-molecule level. These superresolution microscopy techniques are based on detecting optically isolated, fluorescently tagged anti-histone antibodies, fluorescently labeled DNA precursor analogs, or fluorescent dyes bound to DNA. Presently they suffer from various drawbacks such as low labeling efficiency or interference with DNA structure. In this report, we demonstrate that DNA minor groove binding dyes, such as Hoechst 33258, Hoechst 33342, and DAPI, can be effectively employed in single molecule localization microscopy (SMLM) with high optical and structural resolution. Upon ill…
Winter and summer analysis of daylight characteristics in offices
2014
Abstract This paper reports a comparison of the results of daylight measurements carried out in summer and winter in three offices, with different exposures and characteristics, located in Naples (Italy). The aim was to extend and enrich the findings of a previous study which reported the results of summer measurements about desk illuminances and circadian impact. The research project includes measurements carried out in other seasons and a comparison between measured and software simulated values with the final goal of developing design guidelines. This research confirmed that the spectral distributions and CCTs of the light reaching the eye of a person seated at the desk in these offices …
In Vitro Bioactivity of Astaxanthin and Peptides from Hydrolisates of Shrimp (Parapenaeus longirostris) By-Products: From the Extraction Process to B…
2021
Non-edible parts of crustaceans could be a rich source of valuable bioactive compounds such as the carotenoid astaxanthin and peptides, which have well-recognized beneficial effects. These compounds are widely used in nutraceuticals and pharmaceuticals, and their market is rapidly growing, suggesting the need to find alternative sources. The aim of this work was to set up a pilot-scale protocol for the reutilization of by-products of processed shrimp, in order to address the utilization of this valuable biomass for nutraceutical and pharmaceuticals application, through the extraction of astaxanthin-enriched oil and antioxidant-rich protein hydrolysates. Astaxanthin (AST) was obtained using …
Prediction and Surveillance Sampling Assessment in Plant Nurseries and Fields
2022
In this paper, we propose a structured additive regression (STAR) model for modeling the occurrence of a disease in fields or nurseries. The methodological approach involves a Gaussian field (GF) affected by a spatial process represented by an approximation to a Gaussian Markov random field (GMRF). This modeling allows the building of maps with prediction probabilities regarding the presence of a disease in plants using Bayesian kriging. The advantage of this modeling is its computational benefit when compared with known spatial hierarchical models and with the Bayesian inference based on Markov chain Monte Carlo (MCMC) methods. Inference through the use of the integrated nested Laplace app…