Search results for "SSB"

showing 10 items of 537 documents

Synthesis, chemical characterization and biological activity of new histone acetylation/deacetylation specific inhibitors: a novel and potential appr…

2013

Three new triorganotin(IV) complexes of valproic acid (vp1, Me3Sn-valproate; vp2, Bu3Sn-valproate; vp3, Ph3Sn-valproate) have been synthesized and investigated by spectroscopic and biological methods. An anionic, monodentate valproate ligand was observed, ester-like coordinating the tin atom on a tetra-coordinated, monomeric environment. The structures, though, can distort towards a penta-coordination, as a consequence of a long range O center dot center dot center dot Sn interaction. Crystallographic and NMR findings confirm this situation both in solid state and solution. Biological finding evidenced a clear cytotoxic action of the complexes in hepatocellular carcinoma cell cultures: one …

StereochemistryCell SurvivalAntineoplastic AgentsBiochemistryInorganic ChemistryHistonesHistone H3Organotin CompoundsCytotoxic T cellHumansViability assayCells CulturedMOSSBAUER SPECTROSCOPYOrganoTin(IV)biologyX-RAY DIFFRACTIONChemistryMössbauer spectroscopyValproic AcidESI-MSBiological activityAcetylationHep G2 CellsLigand (biochemistry)NMRHistoneBiochemistryApoptosisAcetylationSettore CHIM/03 - Chimica Generale E Inorganicabiology.proteinX-ray spectroscopy
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Syntheses and Solid-State Structures of Some Dialkyltin Derivatives of ?-Methoxy- and ?-Acetoxy-phenylacetic Acids

1996

Several di-n-butyltin and diethyltin biscarboxylates and distannoxanes of α-methoxy- and α-acetoxy-phenylacetic acids were synthesized and (two of) their structures were studied by means of X-ray diffraction analysis as well as by means of IR and Mossbauer spectroscopies. It was shown for {[(n-Bu) 2 - SnOC(O)CH(OMe)Ph] 2 O} 2 that there is an interaction between the OMe group and one of the endocyclic tin atoms, resulting in a distorted pentagonal-bipyramidal geometry with the pentagonal plane defined by five O atoms and an uncommon seven coordination number for this tin atom. Spectral data indicate that biscarboxylates have trans-octahedral structures.

StereochemistryDimerchemistry.chemical_elementGeneral ChemistryCrystal structureChemical synthesisInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryMössbauer spectroscopyX-ray crystallographyMoleculeCarboxylateTinApplied Organometallic Chemistry
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Synthesis of polymeric alkoxides from dialkyltin(IV) oxides and chloral, and their characterization by mössbauer and infrared spectroscopy

1979

Abstract The reaction of (Alk2SnO)n with OCH·CCl3 gives compounds of elemental formula Alk2SnOCH- (CCI3)O (Alk = Bun, Octn), probably by addition of the Sn-O bond to the carbonyl group. Mossbauer parameters suggest the occurrence of five-coordinated Sn, and polymeric structures with bridging three- coordinating oxygens are proposed. The assumption that C2SnO3 units with trigonal bipyramidal type structures are present is consistent with point-charge model rationalization of the quadrupole splitting. Infrared spectra are in keeping with the proposed structures, suggesting, inter alia, bent C Sn C skeletons, but the analysis of possible ν(Sn-O) modes does not provide conclusive evidence for t…

StereochemistryInfrared spectroscopyChloralZonal and meridionalQuadrupole splittingElemental formulaInorganic Chemistrychemistry.chemical_compoundTrigonal bipyramidal molecular geometryCrystallographychemistryMössbauer spectroscopyMaterials ChemistryPhysical and Theoretical ChemistryBenzeneInorganica Chimica Acta
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[Fe(TPT)(2/3){M(I)(CN)2}2]⋅nSolv (M(I) = Ag, Au): new bimetallic porous coordination polymers with spin-crossover properties.

2013

Two new heterobimetallic porous coordination polymers with the formula [Fe(TPT)2/3{MI(CN)2}2]¿nSolv (TPT=[(2,4,6-tris(4-pyridyl)-1,3,5-triazine]; MI=Ag (nSolv=0, 1¿MeOH, 2¿CH2Cl2), Au (nSolv=0, 2¿CH2Cl2)) have been synthesized and their crystal structures were determined at 120¿K and 293¿K by single-crystal X-ray analysis. These structures crystallized in the trigonal R-3m space group. The FeII ion resides at an inversion centre that defines a [FeN6] coordination core. Four dicyanometallate groups coordinate at the equatorial positions, whilst the axial positions are occupied by the TPT ligand. Each TPT ligand is centred in a ternary axis and bridges three crystallographically equivalent Fe…

StereochemistryIronCrystal structure010402 general chemistry01 natural sciencesCatalysismol structure spin crossover pyridyltriazine iron silver gold cyanideIonSpin crossoverMössbauer spectroscopyMolecule[CHIM.COOR]Chemical Sciences/Coordination chemistryBimetallic strippyridyltriazine iron silver gold cyanide prepn crystal structure010405 organic chemistryChemistryOrganic ChemistryGeneral ChemistrySelf-assemblySpin crossover0104 chemical sciencesCoordination polymersCrystallographyFISICA APLICADATernary operationPorositysilver gold bimetallic porous iron pyridyltriazine polymer spin crossoverNatural bond orbitalChemistry (Weinheim an der Bergstrasse, Germany)
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Diphenyltin(IV) complexes of the 5-[(E)-2-(aryl)-1-diazenyl]quinolin-8-olates: Synthesis and multinuclear NMR, 119Sn Mössbauer, electrospray ionizati…

2006

Abstract A series of cis-bis{5-[(E)-2-(aryl)-1-diazenyl]quinolinolato}diphenyltin(IV) complexes have been synthesized and characterized by 1H, 13C, 119Sn NMR, ESI-MS, IR and 119mSn Mossbauer spectroscopic techniques in combination with elemental analysis. The structures of a ligand L6H (i.e., 5-[(E)-2-(4-ethoxyphenyl)-1-diazenyl]quinolin-8-ol) and three diphenyltin(IV) complexes, viz., Ph2Sn(L1)2 · (CH3)2CO (1), Ph2Sn(L4)2 (4) and Ph2Sn(L5)2 (5) (L = 5-[(E)-2-(aryl)-1-diazenyl]quinolin-8-ol: aryl = phenyl – (L1H); 4′-methylphenyl – (L4H) and 4′-bromophenyl – (L5H)) were determined by single crystal X-ray diffraction. In general, the complexes were found to adopt a distorted cis-octahedral a…

StereochemistryLigandArylElectrospray ionizationOrganic Chemistrychemistry.chemical_elementCrystal structureBiochemistryMedicinal chemistryInorganic ChemistrySolventchemistry.chemical_compoundchemistryMössbauer spectroscopyMaterials ChemistryPhysical and Theoretical ChemistryTinSingle crystalJournal of Organometallic Chemistry
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Organometallic Complexes with Biological Molecules: VIII. Synthesis, Solid State andin vivo Investigation of Triorganotin(IV) Derivatives ofL-Homocys…

1997

Several new triorganotin(IV) derivatives of L-homocysteic acid (L-HCAH) with formula R3Sn(L-HCA) (R=Me, nBu, Ph) have been synthesized. Their solid-state configurations were determined by IR and Mossbauer spectroscopy. The tin(IV) atom is five-coordinated in all the complexes, with the L-homocysteic acid behaving as a monoanionic bidentate ligand coordinating the tin(IV) atom through a chelating or bridging carboxylate group. The sulfonate (SO3−) and NH3+ groups of L-homocysteic acid maintain their free acid configuration and hence do not participate to the coordination of the tin(IV) atom. Coordination hypotheses have been checked through the correlation between the Mossbauer parameter iso…

StereochemistryLigandchemistry.chemical_elementGeneral ChemistryCarbon-13 NMRInorganic Chemistrychemistry.chemical_compoundTrigonal bipyramidal molecular geometrySulfonatechemistryMössbauer spectroscopyChelationCarboxylateTinApplied Organometallic Chemistry
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Diorganotin(IV)-2-mercaptopyrimidine complexes

1998

The complexes formed between the diorganotin(IV) moieties, R 2 Sn(IV), and the ligand 2-mercaptopyrimidine, (H)SPym, were investigated. Complexes R 2 SnHal(SPym) and R 2 Sn(SPym) 2 [R = Me, i Pr, n Bu, i Bu, t Bu, cyclohexyl(Cy), Ph] were synthesized, and characterized by elemental analysis. In the solid state, chelation of SPym through S and N donors was established by IR spectroscopy, and the nature of the environment of tin centers was investigated by 119 Sn Mossbauer spectroscopy. From the dynamics of 119 Sn nuclei determined by variable-temperature measurements on representative compounds [Me 2 SnCl(SPym) and Cy 2- SnBr(SPym)], as well as by point-charge model treatment of nuclear quad…

StereochemistryLigandchemistry.chemical_elementInfrared spectroscopyGeneral ChemistryQuadrupole splittingCarbon-13 NMRInorganic ChemistryCrystallographychemistryMössbauer spectroscopyChelationTinCoordination geometryApplied Organometallic Chemistry
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Two- and one-step cooperative spin transitions in Hofmann-like clathrates with enhanced loading capacity

2014

Structural, magnetic, calorimetric and Mo¨ssbauer studies of the cooperative spin crossover naphthalene and nitrobenzene clathrates of the novel FeII Hofmann-like porous metal–organic framework {Fe(bpb)[Pt(CN)4]}2Guest are described (bpb = bis(4-pyridyl)butadiyne).

StereochemistryMetals and AlloysOne-StepGeneral ChemistryCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsNitrobenzeneCrystallographychemistry.chemical_compoundchemistrySpin crossoverFISICA APLICADAMössbauer spectroscopyMaterials ChemistryCeramics and CompositesSpin (physics)NaphthaleneChem. Commun.
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Investigations on organotin, organolead, lead(IV), and lead(II) dithiolates

1985

Abstract Bis(triorganometal) 1,2-dithiolates (R3M)2S2R′ [(HS)2R′ = C7H8S2 for toluene-dithiol-3,4 (H2TDT); M = Sn, Pb; R = Ph; or (HS)2R′ = C10H14S2 for 1,2-dimethyl-4,5-bis(mercaptomethyl)benzene (H2DBB); M = Sn, R = CH3, C6H5; M = Pb, R = C6H5], diorganometal 1,2-dithiolates R2MS2R′ [(HS)2R′ = C6H6S2 for 1,2-dimercaptobenzene (H2DMB); M = Pb, R = CH3, C2H5, C6H5; or (HS)2R′ = H2TDT; M = Sn, R = CH3, C6H5; M = Pb, R = C6H5; or (HS)2R′ = H2DBB; M = Sn, R = CH3, C6H5; M = Pb, R = CH3, C2H2, C6H5; or (HS)2R′ = C8H6N2S2 for 2,3-dimercaptoquinoxaline (H2QDT); M = Pb, R = C6H5] and some lead(IV) and lead(II) dithiolates Pb(S2R′)n [(HS)2R′ = H2DMB, n = 2; (HS)2R′ = H2TDT, n = 2; (HS)2R′ = H2DBB, …

StereochemistryOrganic ChemistrySolid-statechemistry.chemical_elementBiochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundMonomerchemistryMössbauer spectroscopyMaterials ChemistryProton NMRPhysical and Theoretical ChemistryTinBenzeneJournal of Organometallic Chemistry
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1H NMR spectra of Ph2SbX, PhSbX2, and Ph3SbX2 (XCl, Br, I); 121Sb Mössbauer spectra of PhSbX2 and crystal structure of Ph2SbI1

1996

1H NMR spectroscopic data of Ph2SbX, PhSbX2, and Ph3SbX2 (XCl, Br, I) have been determined by iterative simulation. 121Sb Mossbauer spectra of PhSbX2 (XCl, Br, I) have been measured. The synthesis of Ph2SbI is achieved by reaction of Ph2SbCl with NaI in ethanol. The crystal structure of Ph2SbI consists of molecules with pyramidal C2SbI units.

StereochemistryOrganic Chemistrychemistry.chemical_elementCrystal structureBiochemistrySpectral lineInorganic ChemistryCrystallographyAntimonychemistryMaterials ChemistryProton NMRMoleculeMossbauer spectraPhysical and Theoretical ChemistryJournal of Organometallic Chemistry
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