Search results for "Sang"
showing 10 items of 428 documents
Gli analoghi del GnRH ed il Mirena nella terapia del sanguinamento uterino anomalo.
2004
Microsangrados silentes en pacientes con enfermedad cerebrovascular sintomática. Marcadores de riesgo, relación con estado cognitivo y evolución temp…
2015
El gran avance realizado en los últimos años en técnicas de imagen ha permitido la detección de lesiones parenquimatosas subclínicas y aparentemente silentes. Las secuencias de resonancia magnética (RM) con una elevada susceptibilidad magnética para la detección de depósitos con efecto paramagnético como el eco de gradiente (T2*) han permitido la detección de lesiones parenquimatosas que se muestran como focos hipointensos. Estudios anatomopatológicos han demostrado que estas lesiones corresponden a depósitos de hemosiderina en la vecindad de pequeños vasos dañados por un proceso hialinótico. Estas señales constituyen por tanto una evidencia radiológica de microhemorragias o microsangrados …
Impact of assisted reproductive technologies on the regulation of imprinted genes and transposable elements in Human blood cord and placenta
2018
It is estimated that more than five million children have been born by Assisted Reproductive Technologies (ART) worldwide, representing up to 4% of all births. As around 10% of reproductive-aged couples are currently infertile, providing them with treatment options is a public health issue. However, the safety of these techniques has not been fully demonstrated. Notably, the rate of placenta-related adverse pregnancy outcomes could be increased after ART. Moreover, adverse perinatal outcomes, a higher risk of major malformations and imprinting disorders have also been reported in children born following ART. These issues combined raise the question of a potential ART-induced epigenetic vuln…
Paroxysmal nocturnal hemoglobinuria-like phenotype and thrombotic risk in several clinical disorders.
2021
The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors
2020
Essential thrombocythemia is a rare hematological malignancy with good overall survival, but moderate to high risk of developing arterial or venous thrombosis lifelong. Different thrombotic risk scores for patients with essential thrombocythemia have been proposed, but only one of them (the IPSET-t scoring system) takes into account the classical cardiovascular risk factors as one of the scoring items. Currently, in clinical practice, the presence of cardiovascular risk factors in patients with diagnosis of ET rarely determines the decision to initiate cytoreductive therapies. In our study, we compared different risk models to estimate the thrombotic risk of 233 ET patients and the role of …
Utilisation of natural carotenoids from Momordica cochinchinensis (gac) as health compounds : extraction and bioactvity depending on the origin and o…
2014
The aril of Momordica cochinchinensis (gac), plant from the Cucurbitaceae family, is the richest source of lycopene and β-carotene, which are a strong antioxidant and a pro-vitamin A, respectively, interesting for health-complements. First, a process of soft extraction-fractionation was developed for extracting effectively the natural carotenoids from gac without loss of their original quality. Then, the lycopene and β-carotene extracted from gac were analyzed and characterized. At least 95% of the extracts were composed of the all-trans isomer. They were not degraded during the heat-treatment mimicking formulation processing. Their thermal stereo-mutation was evaluated. Lycopene is more an…
Stratification dépendante du temps dans la modélisation de Cox en tant que méthode de prise en compte d’interventions répétées dans la prise en charg…
2016
International audience; IntroductionLa transfusion de concentrés de globules rouges (CGR) est le traitement symptomatique de l’anémie et contribue à l’oxygénation des tissus au cours de pathologies sévères. Nous menons une recherche sur l’effet des caractéristiques des CGRs sur la survie des patients dans les CHU de Besançon et Dijon : l’étude STeF-BFC. Nous étudions l’effet de la durée de conservation (DC) et du sexe du donneur (SD) des CGR sur la survie à un an de patients de chirurgie cardiovasculaire. Dans ce type d’étude, le nombre de CGR reçus est un facteur de confusion majeur. Il s’agit d’un biais d’indication mais aussi un biais de survivant (il faut avoir survécu jusqu’à la transf…
Trasplante de sangre cordón umbilical de donante no emparentado en adultos con enfermedades hematológicas malignas
2013
En los últimos años se ha producido un gran incremento de la actividad de trasplante de sangre de cordón umbilical (TSCU) en adultos. Diferentes estudios han demostrado que el TSCU es viable en pacientes adultos con enfermedades hematológicas malignas y se debe considerar como alternativa a la MO o SP de DNE adulto. Los objetivos de este trabajo de tesis doctoral fueron analizar los resultados terapéuticos de una amplia serie de pacientes adultos con neoplasias hematológicas sometidos a TSCU, así como analizar las variables independientes (explicativas) que pudieran tener un impacto en los resultados mediante métodos de análisis univariante y multivariante. Se analizaron 199 pacientes adult…
Santo Dominguito de Val: La ?tradición? como arma arrojadiza a disposición de los poderes establecidos
2019
This study focuses, from a short story of the blood libel of Saint Dominguito de Val, on answering the questions of when and why the ?tradition? was made about this saint, and the specific moments of his Revitalization until the end of the 17th century. Although the short story of the death of this infant has been occupied by the most diverse writers of the sixteenth and seventeenth centuries, we take as reference the master Espés and the chroniclers Blancas, Andrés de Uztarroz and Dormer.
EPIDEMIOLOGY OF BOUTONNEUSE FEVER IN WESTERN SICILY
1986
The distribution and prevalence of spotted fever group rickettsial infection in the ixodid dog tick Rhipicephalus sanguineus were found to occur at a rate of 19.7% with variation related to geographic and sociooccupational factors. A higher rate of infection was demonstrated in ticks removed from dogs associated with documented cases of boutonneuse fever. The results fit into available clinical and seroepidemiologic data on Rickettsia conorii infection in western Sicily.