Search results for "Sensor"
showing 10 items of 4594 documents
Immuno-MALDI-MS in Human Plasma and on-Chip Biomarker Characterizations at the Femtomole Level
2012
Immuno-SPR-MS is the combination of immuno-sensors in biochip format with mass spectrometry. This association of instrumentation allows the detection and the quantification of proteins of interest by SPR and their molecular characterization by additional MS analysis. However, two major bottlenecks must be overcome for a wide diffusion of the SPR-MS analytical platform: (i) To warrant all the potentialities of MS, an enzymatic digestion step must be developed taking into account the spot formats on the biochip and (ii) the biological relevancy of such an analytical solution requires that biosensing must be performed in complex media. In this study, we developed a procedure for the detection …
Implantación coclear bilateral en niños. Comparativa con la implantación unilateral y la estimulación bimodal
2020
Introducción El diagnóstico precoz de las enfermedades supone el primer elemento para llegar a un tratamiento eficaz. Esta actuación es mucho más determinante en los casos de hipoacusia en recién nacidos/as, dada la estrecha relación existente entre audición y lenguaje. En realidad, sólo disponemos de los primeros cinco o seis años para evitar que las pérdidas de audición tengan efectos permanentes en el desarrollo de ese lenguaje. Esto es debido al período crítico de aprendizaje, en el cual quedan selladas las características morfológicas y funcionales de las áreas corticales del lenguaje. Realizar una detección precoz de los problemas auditivos permite llevar a cabo el tratamiento lo ante…
Salt release monitoring with specific sensors in "in vitro" oral and digestive environments from soft cheeses
2012
International audience; The objective of the present work is to demonstrate the interest and the feasibility of the measurement of NaCl concentrations in soft cheeses and in particular an in vitro digestion process by the use of chemical sensors. The analyzed matrices were the commercial Italian mozzarella cheeses and domestic cheese base models. The classification of mozzarellas was performed according to their salinity, while the breakdown of cheese base models has been followed both at initial steps of digestion in artificial mouth dispositive mimicking the oral sphere and in a gut-imitating digester (TIM-1). During the breakdown of soft cheese in the digester, the estimated values for N…
Sensoro spēju veicināšanas iespējas 1,5-2 gadus veciem bērniem pedagoģiskajā procesā
2021
Bakalaura darbs: Sensoro spēju veicināšanas iespējas 1,5 - 2 gadus veciem bērniem pedagoģiskajā procesā. Darba autors: Jolanta Vasiļevska Darba zinātniskā vadītāja: Asoc. Prof. Dr. Paed. Mg. Art. Ilze Briška Pētījuma mērķis: Praktiski pārbaudīt digitālo ierīču lietošanas efektivitāti, veicinot bērna redzes attīstību. Darba apjoms: 51 lpp, 6 tabulas, 12 attēli, 38 izmantotās literatūras un informācijas avoti Darba uzdevumi: 1.Analizēt teorētiskās pedagogu un psihologu atziņas par sensorajām spējām; 2.Teorētiski izzināt sensoro spēju attīstību 1-2 gadu veciem bērniem; 3.Apkopot pedagoģiskās darbības iespējas sensoro spēju veicināšanai; 4.Praktiski pārbaudīt digitālo ierīču lietošanas efektivi…
Universālas inerciālo mērījumu sistēmas programmatūra
2020
Inerciālie sensori mūsdienās guvuši lielu atsaucību industrijas uzņēmumu kā arī patērētāju vidū. Tie tiek lietoti ne tikai gala produktā, bet arī ražošanas procesā, nodrošinot papildus kvalitātes kontroli7. Šādas, universālas, ierīces izstrāde varētu šķist mulsinoša, jo mūsdienās šie sensori ir atrodami katrā mobīlajā ierīcē, taču eksistē ļoti daudzi lietojumgadījumi, kad ierīcei, piemēram, jāspēj darboties ar ļoti zemu enerģijas patēriņu vai ļoti zemu aizkavi, ko eksistējošie risinājumi nespēj nodrošināt. Autors uzskata, ka šajā brīdī aparatūras cena un veiktspēja ir pietiekamas, lai būtu iespējams radīt universālu ierīci šādu mērījumu un daļējas to analīzes veikšanai. Maģistra darba mērķi…
Classification of healthy, Alzheimer and Parkinson populations with a multi-branch neural network
2022
Signal processing, for delimitation of the target events and parametrization, is usually required when instrumented assessment is conducted to determine an individual’s functional status. However, these procedures may rule out relevant information obtained by sensors. To prevent this, the use of models based on neural networks that automatically extract relevant features from the raw signal may improve the characterization of the functional status. Thus, the aim of the study was to determine the classification accuracy of a multi-head convolutional layered neural network (CNN) using a simple functional mobility test in people with different conditions. The raw data from an inertial sensor e…
How salience enhances inhibitory control : An analysis of electro-cortical mechanisms
2023
Stop-signal tasks (SSTs) combined with human electro-cortical recordings (Event-Related Potentials, ERPs) have revealed mechanisms associated with successful stopping (relative to failed), presumably contributing to inhibitory control. The corresponding ERP signatures have been labeled stop N1 (+/- 100-ms latency), stop N2 (200 ms), and stop P3 (160–250 ms), and argued to reflect more sensory-specific (N1) versus more generic (N2, P3) mechanisms. However, stop N1 and stop N2, as well as latencies of stop-P3, appear to be quite inconsistent across studies. The present work addressed the possible influence of stop-signal salience, expecting high salience to induce clear stop N1s but reduced s…
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function
2019
Catalysis makes chemical and biochemical reactions kinetically accessible. From a technological point of view, organic, inorganic, and biochemical catalysis is relevant for several applications, from industrial synthesis to biomedical, material, and food sciences. A heterogeneous catalyst, i.e., a catalyst confined in a different phase with respect to the reagents’ phase, requires either its physical confinement in an immobilization matrix or its physical adsorption on a surface. In this review, we will focus on the immobilization of biological catalysts, i.e., enzymes, by comparing hard and soft immobilization matrices and their effect on the modulation of the catalysts’ function. Indeed, …
An Off-On-Off Fluorescent Sensor for pH Windows Based on the 13aneN4-Zn 2+ System
2016
International audience; The new ligand L was prepared and features a 13-membered tetraaza macrocyclic ring with a 1,8-naphthalimide fluorophore appended to a C atom of its backbone. The protonation constants of L as well as its complexation constants with Zn2+ ions were determined in 1:1 water/methanol solutions by potentiometric titrations. Fluorimetric pH titrations were performed with L alone and L in the presence of Zn2+ ions (1:1), and the species distributions (%) versus pH were compared. A window-shaped fluorescence trend was observed with pH for the L/Zn2+ system, which behaves as an off-on-off pH sensor. The on window is centred in the 6.5-7.5 pH range, in correspondence with the f…
A new simple chromo-fluorogenic probe for NO2 detection in air.
2015
[EN] A new chromo-fluorogenic probe, consisting of a biphenyl derivative containing both a silylbenzyl ether and a N,N-dimethylamino group, for NO2 detection in the gas phase has been developed. A clear colour change from colourless to yellow together with an emission quenching was observed when the probe reacted with NO2. A limit of detection to the naked eye of about 0.1 ppm was determined and the system was successfully applied to the detection of NO2 in realistic atmospheric conditions.